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Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells

Data up to Jan 2025

Published2001
Citations1,739
References37

Total Citations Per Year

Abstract

References (37)

Dynamics of mitochondria in living cells: Shape changes, dislocations, fusion, and fission of mitochondria

1994 • 870 citations

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

1995 • 816 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic

1991 • 757 citations

The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast

1999 • 753 citations

A Human Dynamin-related Protein Controls the Distribution of Mitochondria

1998 • 711 citations

Dnm1p Gtpase-Mediated Mitochondrial Fission Is a Multi-Step Process Requiring the Novel Integral Membrane Component Fis1p

2000 • 698 citations

Dynamin Undergoes a GTP-Dependent Conformational Change Causing Vesiculation

1998 • 665 citations

Targeted Disruption of Mouse Conventional Kinesin Heavy Chain kif5B, Results in Abnormal Perinuclear Clustering of Mitochondria

1998 • 643 citations

C. elegans Dynamin-Related Protein DRP-1 Controls Severing of the Mitochondrial Outer Membrane

1999 • 638 citations

Division versus Fusion: Dnm1p and Fzo1p Antagonistically Regulate Mitochondrial Shape

1999 • 517 citations

GTPase activity of dynamin and resulting conformation change are essential for endocytosis

2001 • 451 citations

The Dynamin-related GTPase, Dnm1p, Controls Mitochondrial Morphology in Yeast

1998 • 416 citations

Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin.

1995 • 400 citations

Mdv1p Is a Wd Repeat Protein That Interacts with the Dynamin-Related Gtpase, Dnm1p, to Trigger Mitochondrial Division

2000 • 368 citations

Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis

1999 • 364 citations

Chloroplast Division in Higher Plants Requires Members of Two Functionally Divergent Gene Families with Homology to Bacterial ftsZ

1998 • 330 citations

The Dynamin-like Protein DLP1 Is Essential for Normal Distribution and Morphology of the Endoplasmic Reticulum and Mitochondria in Mammalian Cells

1999 • 296 citations

Functional diversity in the dynamin family

1999 • 256 citations

Domain structure and intramolecular regulation of dynamin GTPase

1997 • 239 citations

Dynamin:Gtp Controls the Formation of Constricted Coated Pits, the Rate Limiting Step in Clathrin-Mediated Endocytosis

2000 • 232 citations

MITOCHONDRIAL DYNAMICS IN YEAST

1998 • 185 citations

Gag3p, an Outer Membrane Protein Required for Fission of Mitochondrial Tubules

2000 • 175 citations

A Novel Dynamin-like Protein Associates with Cytoplasmic Vesicles and Tubules of the Endoplasmic Reticulum in Mammalian Cells

1998 • 175 citations

Mitochondrial FtsZ in a Chromophyte Alga

2000 • 172 citations

A Model for Dynamin Self-assembly Based on Binding Between Three Different Protein Domains

1999 • 133 citations

DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast.

1995 • 126 citations

Identification and Subcellular Localization of a Novel Mammalian Dynamin-Related Protein Homologous to Yeast Vps1p and Dnm1p

1997 • 113 citations

Identification and functional characterization of a novel human protein highly related to the yeast dynamin-like GTPase Vps1p

1998 • 103 citations

Dynamin Assembles into Spirals under Physiological Salt Conditions upon the Addition of GDP and γ-Phosphate Analogues

1997 • 100 citations

Structure of mouse Mx1 protein. Molecular assembly and GTP-dependent conformational change

1993 • 71 citations

Visualization of Mitochondrial Protein Import in Cultured Mammalian Cells with Green Fluorescent Protein and Effects of Overexpression of the Human Import Receptor Tom20

1997 • 71 citations

Intermolecular and Interdomain Interactions of a Dynamin-related GTP-binding Protein, Dnm1p/Vps1p-like Protein

1999 • 68 citations

Immunochemical analysis of rough and smooth microsomes from rat liver. Segregation of docking protein in rough membranes

1985 • 57 citations

Mechanism of Activation of the Caenorhabditis elegans ras Homologue let-60 by a Novel, Temperature-Sensitive, Gain-of-Function Mutation

1997 • 55 citations

Dymple, a Novel Dynamin-like High Molecular Weight GTPase Lacking a Proline-rich Carboxyl-terminal Domain in Mammalian Cells

1998 • 54 citations

Experimental production of ?septa? and apparent subdivision of muscle mitochondria

1980 • 24 citations

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Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells (2001) – Molecular Biology of the Cell | Metascience Observatory Explorer