Visualization of Mitochondrial Protein Import in Cultured Mammalian Cells with Green Fluorescent Protein and Effects of Overexpression of the Human Import Receptor Tom20

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1991 • 5,120 citations

Mitochondrial protein import

1989 • 820 citations

Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells

1995 • 493 citations

Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera.

1996 • 376 citations

Localization, trafficking, and temperature-dependence of the Aequorea green fluorescent protein in cultured vertebrate cells.

1995 • 240 citations

Double labelling of subcellular structures with organelle-targeted GFP mutants in vivo

1996 • 226 citations

The protein import receptor of mitochondria

1995 • 153 citations

Structure of the Human Ornithine Transcarbamylase Gene1

1988 • 121 citations

Mechanisms of protein import across the mitochondrial outer membrane

1996 • 121 citations

Protein import into mitochondria: a paradigm for the translocation of polypeptides across membranes

1993 • 84 citations

Identification of the human mitochondrial protein import receptor, huMas20p. Complementation of Δmas20 in yeast

1995 • 83 citations

Characterization of a novel component of the peroxisomal protein import apparatus using fluorescent peroxisomal proteins.

1996 • 77 citations

Synthesis, intracellular transport, and processing of the precursors for mitochondrial ornithine transcarbamylase and carbamoyl-phosphate synthetase I in isolated hepatocytes.

1981 • 76 citations

Genetic and biochemical dissection of the mitochondrial protein-import machinery

1995 • 71 citations

Biosynthesis and topogenesis of aspartate aminotransferase isoenzymes in chicken embryo fibroblasts. The precursor of the mitochondrial isoenzyme is either imported into mitochondria or degraded in the cytosol.

1982 • 63 citations

Role of Heat Shock Cognate 70 Protein in Import of Ornithine Transcarbamylase Precursor into Mammalian Mitochondria

1995 • 58 citations

A human homolog of the mitochondrial protein import receptor Mom19 can assemble with the yeast mitochondrial receptor complex

1995 • 50 citations

A Receptor for the Import of Proteins into Human Mitochondria

1996 • 46 citations

The ornithine transcarbamylase leader peptide directs mitochondrial import through both its midportion structure and net positive charge.

1987 • 44 citations

Expression of amplified DNA sequences for ornithine transcarbamylase in HeLa cells: arginine residues may be required for mitochondrial import of enzyme precursor.

1985 • 37 citations

Expression and Stabilization of Microinjected Plasmids Containing the Herpes Simplex Virus Thymidine Kinase Gene and Polyoma Virus DNA in Mouse Cells

1983 • 35 citations

Mitochondrial import and processing of mutant human ornithine transcarbamylase precursors in cultured cells.

1988 • 26 citations

Expression and Stabilization of Microinjected Plasmids Containing the Herpes Simplex Virus Thymidine Kinase Gene and Polyoma Virus DNA in Mouse Cells

1983 • 16 citations

Mitochondrial alterations induced by aspirin in rat hepatocytes expressing mitochondrially targeted green fluorescent protein (mtGFP)

1996 • 8 citations

Transport of mitochondrial precursor proteins: Their conformational competence and related factors.

1989 • 2 citations