Removal of MAP4 from microtubules in vivo produces no observable phenotype at the cellular level.
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References (67)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
1976 • 225,752 citations
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.
1979 • 54,907 citations
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 • 47,043 citations
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
1988 • 6,107 citations
Dynamic instability of microtubule growth
1984 • 3,187 citations
Microtubules containing acetylated alpha-tubulin in mammalian cells in culture.
1987 • 833 citations
Altered microtubule organization in small-calibre axons of mice lacking tau protein
1994 • 742 citations
Tau protein function in living cells.
1986 • 727 citations
The Primary Structure and Heterogeneity of Tau Protein from Mouse Brain
1988 • 671 citations
Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons
1990 • 638 citations
Tubulin dynamics in cultured mammalian cells.
1984 • 489 citations
Microtubule-Associated Protein MAP2 Shares a Microtubule Binding Motif with Tau Protein
1988 • 476 citations
Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs
1990 • 446 citations
Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts
1990 • 444 citations
PURIFICATION OF TUBULIN AND ASSOCIATED HIGH MOLECULAR WEIGHT PROTEINS FROM PORCINE BRAIN AND CHARACTERIZATION OF MICROTUBULE ASSEMBLY IN VITRO*
1975 • 423 citations
Microtubule organization and dynamics dependent on microtubule-associated proteins
1994 • 411 citations
CLIP-170 links endocytic vesicles to microtubules
1992 • 367 citations
Real-time observations of microtubule dynamic instability in living cells.
1988 • 364 citations
Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.
1989 • 354 citations
Microtubule dynamics in interphase cells.
1986 • 331 citations
Direct observation of microtubule dynamics in living cells
1988 • 318 citations
Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules.
1987 • 297 citations
Kinetochore microtubule dynamics and the metaphase-anaphase transition.
1995 • 292 citations
Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau
1989 • 281 citations
Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics.
1995 • 279 citations
Dynamic and stable populations of microtubules in cells.
1987 • 273 citations
Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level.
1988 • 272 citations
Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts.
1982 • 262 citations
Differential turnover of tyrosinated and detyrosinated microtubules.
1987 • 250 citations
A microtubule-binding protein associated with membranes of the Golgi apparatus.
1986 • 234 citations
Expression of tau protein in non-neuronal cells: microtubule binding and stabilization
1992 • 215 citations
Chapter 7 Fluorescent Labeling of Mitochondria
1988 • 209 citations
Inhibition of MAP2 expression affects both morphological and cell division phenotypes of neuronal differentiation
1991 • 207 citations
Polymerization of tubulin in vivo: direct evidence for assembly onto microtubule ends and from centrosomes.
1985 • 142 citations
Detyrosination of alpha tubulin does not stabilize microtubules in vivo [published erratum appears in J Cell Biol 1990 Sep;111(3):1325-6]
1990 • 141 citations
Non-neuronal 210×103Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau
1991 • 136 citations
Self-assembly of microtubules in extracts of cultured HeLa cells and the identification of HeLa microtubule-associated proteins.
1979 • 134 citations
A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences.
1991 • 127 citations
Immunoprecipitation of nonerythrocyte spectrin within live cells following microinjection of specific antibodies: relation to cytoskeletal structures.
1984 • 125 citations
Molecular cloning of a ubiquitously distributed microtubule-associated protein with Mr 190,000.
1990 • 122 citations
Proteins of the mammalian mitotic spindle: phosphorylation/dephosphorylation of MAP-4 during mitosis
1991 • 121 citations
The yeast actin cytoskeleton
1994 • 114 citations
Intrinsic microtubule stability in interphase cells
1994 • 113 citations
Regulation of a major microtubule-associated protein by MPF and MAP kinase.
1992 • 112 citations
Molecular characterization of two functional domains of CLIP-170 in vivo
1994 • 110 citations
Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts
1992 • 109 citations
The non-tubulin component of microtubule protein oligomers. Effect on self-association and hydrodynamic properties.
1978 • 106 citations
Widespread distribution of a 210,000 mol wt microtubule-associated protein in cells and tissues of primates.
1980 • 104 citations
Immunofluorescence localization of HeLa cell microtubule-associated proteins on microtubules in vitro and in vivo.
1980 • 102 citations
Microtubule stabilization by assembly‐promoting microtubule‐associated proteins: A repeat performance
1992 • 101 citations
Functional analyses of the domain structure of microtubule-associated protein-4 (MAP-U)
1991 • 100 citations
Effect on microtubule dynamics of XMAP230, a microtubule-associated protein present in Xenopus laevis eggs and dividing cells [published erratum appears in J Cell Biol 1995 Mar;128(5):following 988]
1994 • 87 citations
Chapter 5 A Fluorescent Derivative of Ceramide: Physical Properties and Use in Studying the Golgi Apparatus of Animal Cells
1988 • 83 citations
Purification and reconstitution of HeLa cell microtubules
1980 • 78 citations
Differential Expression of Alternatively Spliced Forms of MAP4: A Repertoire of Structurally Different Microtubule-Binding Domains
1995 • 77 citations
Quantitative determination of the proportion of microtubule polymer present during the mitosis-interphase transition
1994 • 76 citations
Stable expression of heterologous microtubule-associated proteins (MAPs) in Chinese hamster ovary cells: evidence for differing roles of MAPs in microtubule organization.
1994 • 75 citations
A microtubule-associated protein antigen unique to mitotic spindle microtubules in PtK1 cells.
1983 • 71 citations
Non-motor microtubule-associated proteins
1991 • 64 citations
Purification and characterization of ensconsin, A novel microtubule stabilizing protein
1994 • 57 citations
Cell cycle-dependent changes in the dynamics of MAP 2 and MAP 4 in cultured cells.
1989 • 52 citations
Genetic analysis of a Drosophila microtubule-associated protein.
1992 • 40 citations
Microtubule destabilization by cdc2/H1 histone kinase: Phosphorylation of a “Pro-rich region” in the microtubule-binding domain of MAP-4
1991 • 36 citations
Use of a heat-stable microtubule-associated protein class-specific antibody to investigate the mechanism of microtubule binding.
1991 • 12 citations
Antibodies against vertebrate microfilament proteins in the analysis of cellular motility and adhesion
1991 • 12 citations
Decoration of microtubules by fluorescently labeled microtubule‐associated protein 2 (MAP2) does not interfere with their spatial organization and progress through mitosis in living fibroblasts
1986 • 9 citations