Regulation of Corticotropin-Releasing Hormone Type 2 Receptors by Multiple Promoters and Alternative Splicing: Identification of Multiple Splice Variants

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

1995 • 1,469 citations

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1990 • 1,362 citations

Physiology and pharmacology of corticotropin-releasing factor.

1991 • 1,138 citations

Expression cloning of a human corticotropin-releasing-factor receptor.

1993 • 923 citations

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1

1998 • 919 citations

Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression

1995 • 917 citations

Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress

2000 • 836 citations

Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

1995 • 836 citations

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

1988 • 771 citations

Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor

2001 • 647 citations

Multiple D2 dopamine receptors produced by alternative RNA splicing

1989 • 642 citations

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes.

1989 • 605 citations

Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2

2000 • 591 citations

Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin

1983 • 535 citations

Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary.

1994 • 514 citations

Deletion of Crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2

2000 • 490 citations

Predicting Pol II Promoter Sequences using Transcription Factor Binding Sites

1995 • 446 citations

CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues.

1995 • 444 citations

cDNA Cloning of an orphan opiate receptor gene family member and its splice variant

1994 • 379 citations

A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle.

1995 • 373 citations

Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.

1990 • 343 citations

Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors

1993 • 320 citations

Corticotropin-Releasing Hormone in Humans*

1992 • 283 citations

Cloning and expression of a novel mouse somatostatin receptor (SSTR2B)

1992 • 270 citations

Molecular Identification and Analysis of a Novel Human Corticotropin-Releasing Factor (CRF) Receptor: The CRF2γ Receptor

1998 • 258 citations

Corticotropin-Releasing Hormone Directly and Preferentially Stimulates Dehydroepiandrosterone Sulfate Secretion by Human Fetal Adrenal Cortical Cells*

1998 • 223 citations

ALTERNATIVE PROMOTERS IN DEVELOPMENTAL GENE EXPRESSION

1987 • 204 citations

Alternative splicing of CRH‐R1 receptors in human and mouse skin: identification of new variants and their differential expression

2001 • 179 citations

Molecular Cloning of a Novel Variant of the Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Receptor That Stimulates Calcium Influx by Activation of L-type Calcium Channels

1996 • 162 citations

Expression of Three Isoforms of cGMP-Binding cGMP-Specific Phosphodiesterase (PDE5) in Human Penile Cavernosum

2000 • 159 citations

Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia.

1993 • 156 citations

Expression of Urocortin and Corticotropin-Releasing Factor Receptor Subtypes in the Human Heart

2002 • 140 citations

Why are human G-protein-coupled receptors predominantly intronless?

1999 • 134 citations

Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing.

1996 • 130 citations

7TM receptors: the splicing on the cake

1999 • 118 citations

A new functional isoform of the human CRF2 receptor for corticotropin-releasing factor

1997 • 116 citations

A Novel Spliced Variant of the Type 1 Corticotropin-Releasing Hormone Receptor with a Deletion in the Seventh Transmembrane Domain Present in the Human Pregnant Term Myometrium and Fetal Membranes

1999 • 116 citations

Interpolated markov chains for eukaryotic promoter recognition.

1999 • 115 citations

Abnormal processing of the human cholecystokinin receptor gene in association with gallstones and obesity

1995 • 113 citations

The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences.

1995 • 99 citations

Altered expression of type 2 CRH receptor mRNA in the VMH by glucocorticoids and starvation

1998 • 89 citations

A Variant of the Human Corticotropin-Releasing Factor (CRF) Receptor: Cloning, Expression, and Pharmacology

1994 • 82 citations

Recognition of regulatory regions in genomic sequences

1994 • 71 citations

Regulation of Corticotropin-Releasing Factor Receptor Type 2β Messenger Ribonucleic Acid in the Rat Cardiovascular System by Urocortin, Glucocorticoids, and Cytokines*

2000 • 69 citations

Expression of CRHR1 and CRHR2 in Mouse Pituitary and Adrenal Gland: Implications for HPA System Regulation

2001 • 67 citations

Human Corticotropin-Releasing Hormone Receptor: Differences in Subtype Expression between Pregnant and Nonpregnant Myometria¹

1998 • 66 citations

Enhanced Cleavage of an Atypical Intron of Dopamine D₃-Receptor Pre-mRNA in Chronic Schizophrenia

1996 • 59 citations

Urocortin and Corticotropin-Releasing Factor Receptor Expression in Normal Cycling Human Ovaries¹

2001 • 57 citations

Cloning and Characterization of a Short Variant of the Corticotropin-Releasing Factor Receptor Subtype from Rat Amygdala

1999 • 53 citations

Stress-Induced Genetic Expression of a Selective Corticotropin-Releasing Factor-Receptor Subtype Within the Rat Ovaries: An Effect Dependent on the Ovulatory Cycle1

1995 • 51 citations

Identification of human growth hormone-releasing hormone receptor splicing variants.

1995 • 44 citations

The Drosophila PAR Domain Protein 1 (Pdp1) Gene Encodes Multiple Differentially Expressed mRNAs and Proteins through the Use of Multiple Enhancers and Promoters

2000 • 44 citations

Urocortin and Corticotropin-Releasing Factor Receptor Expression in Normal Cycling Human Ovaries

2001 • 43 citations

Expression of corticotrophin-releasing hormone receptor mRNA and protein in the human myometrium

1998 • 41 citations

Human Corticotropin-Releasing Hormone Receptor: Differences in Subtype Expression between Pregnant and Nonpregnant Myometria

1998 • 40 citations

Altered expression of dopamine D2 receptor rnRNA splice variants in brain and pituitary of spontaneously hypertensive rats

1995 • 38 citations

Identification of human growth hormone-releasing hormone receptor splicing variants

1995 • 35 citations

Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.

1993 • 35 citations

Localization of the Human CRF2 Receptor to 7p21–p15 by Radiation Hybrid Mapping and FISH Analysis

1997 • 34 citations

Isolation of a Liver-Specific Promoter for Human Growth Hormone Receptor Gene

1997 • 34 citations

Localization and Characterization of a Short Isoform of the Corticotropin-Releasing Factor Receptor Type 2α (CRF2α-tr) in the Rat Brain

2001 • 32 citations

The Human Corticotropin-Releasing Factor Receptor (CRHR) Gene Maps to Chromosome 17q12-q22

1995 • 32 citations

Identification of Three Alternative First Exons and an Intronic Promoter of Human PDE5A Gene

2000 • 27 citations

Alternative promoter usage and splicing options result in the differential expression of mRNAs encoding four isoforms of chicken VBP, a member of the PAR subfamily of bZIP transcription factors

1994 • 23 citations

Identification and expression of a variant isoform of the levocabastine‐sensitive neurotensin receptor in the mouse central nervous system

1997 • 21 citations

The Carboxyl-terminal Anchorage Domain of the Turkey β1-Adrenergic Receptor Is Encoded by an Alternatively Spliced Exon

1995 • 19 citations

Cloning and characterization of two isoforms of the zebrafish thyrotroph embryonic factor (tefα and tefβ)

1998 • 10 citations