Overexpression of Interleukin-10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor–Deficient Mice by Altering Lymphocyte and Macrophage Phenotypes

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Atherosclerosis: Basic Mechanisms

1995 • 1,697 citations

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

1999 • 987 citations

IFN-gamma potentiates atherosclerosis in ApoE knock-out mice.

1997 • 855 citations

Protective Role of Interleukin-10 in Atherosclerosis

1999 • 805 citations

Structural Identification by Mass Spectrometry of Oxidized Phospholipids in Minimally Oxidized Low Density Lipoprotein That Induce Monocyte/Endothelial Interactions and Evidence for Their Presence in Vivo

1997 • 751 citations

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

1990 • 627 citations

Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.

1995 • 596 citations

Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation

1998 • 594 citations

A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice.

1998 • 525 citations

Activation of Monocyte/Macrophage Functions Related to Acute Atheroma Complication by Ligation of CD40

1997 • 493 citations

Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis.

1996 • 428 citations

Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice.

1998 • 421 citations

Interleukin-10 Blocks Atherosclerotic Events In Vitro and In Vivo

1999 • 399 citations

Exogenous Interferon-γ Enhances Atherosclerosis in Apolipoprotein E−/− Mice

2000 • 361 citations

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

2000 • 353 citations

Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice.

1997 • 330 citations

The Role of Interleukin 12 in the Development of Atherosclerosis in ApoE-Deficient Mice

1999 • 307 citations

Immunoglobulin treatment reduces atherosclerosis in apo E knockout mice.

1998 • 304 citations

In Vivo Downregulation of T Helper Cell 1 Immune Responses Reduces Atherogenesis in Apolipoprotein E-Knockout Mice

2001 • 288 citations

Altered Immune Responses in Interleukin 10 Transgenic Mice

1997 • 279 citations

Fas Is Expressed in Human Atherosclerotic Intima and Promotes Apoptosis of Cytokine-Primed Human Vascular Smooth Muscle Cells

1997 • 270 citations

Expression of Interleukin-10 in Advanced Human Atherosclerotic Plaques

1999 • 267 citations

Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype

2000 • 263 citations

Adenoviral Transfer of the Viral IL-10 Gene Periarticularly to Mouse Paws Suppresses Development of Collagen-Induced Arthritis in Both Injected and Uninjected Paws

1999 • 204 citations

Macrophages are a significant source of type 1 cytokines during mycobacterial infection

1999 • 194 citations

Lymphocyte Populations in Atherosclerotic Lesions of ApoE −/− and LDL Receptor −/− Mice

1996 • 192 citations

Chemokine Receptor CCR2 Expression and Monocyte Chemoattractant Protein-1–Mediated Chemotaxis in Human Monocytes

1998 • 176 citations

ChlamydiapneumoniaeInhibits Apoptosis in Human Peripheral Blood Mononuclear Cells Through Induction of IL-10

2000 • 129 citations

CD40 Signaling of Monocyte Inflammatory Cytokine Synthesis through an ERK1/2-dependent Pathway

1999 • 105 citations

Effect of γ-Irradiation and Bone Marrow Transplantation on Atherosclerosis in LDL Receptor-Deficient Mice

2001 • 103 citations

Molecular Determinants of Atherosclerotic Plaque Vulnerability^a

1997 • 87 citations

Enhancement of Macrophage Colony-Stimulating Factor–Induced Growth and Differentiation of Human Monocytes by Interleukin-10

1997 • 85 citations

The Role of Oxidized LDL in Atherogenesis: Immunological Response and Anti‐phospholipid Antibodies

1997 • 51 citations

Interferon-γ-Secreting T-Cell Populations in Rejecting Murine Cardiac Allografts

1998 • 43 citations

Role of Leukocyte-Specific LDL Receptors on Plasma Lipoprotein Cholesterol and Atherosclerosis in Mice

1997 • 43 citations