The Role of Oxidized LDL in Atherogenesis: Immunological Response and Anti‐phospholipid Antibodies

Beyond Cholesterol

1989 • 6,533 citations

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Atherosclerosis: Basic Mechanisms

1995 • 1,697 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

Low density lipoprotein undergoes oxidative modification in vivo.

1989 • 1,537 citations

The oxidation hypothesis of atherosclerosis

1994 • 1,418 citations

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 • 1,332 citations

CD36 is a receptor for oxidized low density lipoprotein

1993 • 1,271 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Expression cloning of SR-BI, a CD36-related class B scavenger receptor.

1994 • 818 citations

Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions.

1991 • 669 citations

Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.

1996 • 557 citations

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

1984 • 547 citations

LDL-induced cytotoxicity and its inhibition by HDL in human vascular smooth muscle and endothelial cells in culture

1979 • 512 citations

Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.

1995 • 412 citations

Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.

1996 • 354 citations

Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells.

1995 • 311 citations

The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68.

1995 • 310 citations

Anti-Cardiolipin Antibodies and Risk of Myocardial Infarction in a Prospective Cohort of Middle-Aged Men

1995 • 306 citations

Role of Oxidized LDL and Antioxidants in Atherosclerosis

1995 • 164 citations

Recognition of oxidatively damaged erythrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein.

1994 • 151 citations

Pre-eclampsia and serum antibodies to oxidised low-density lipoprotein

1994 • 142 citations

Oxidized lipoproteins, altered cell function and atherosclerosis

1994 • 138 citations

Immune Mechanisms in Atherogenesis

1994 • 49 citations

Immune Functions of the Vessel Wall

2024 • 10 citations