Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

1995 • 93,704 citations

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Practical Statistics for Medical Research.

1992 • 12,008 citations

Practical Statistics for Medical Research

1990 • 9,667 citations

Unmutated Ig VH Genes Are Associated With a More Aggressive Form of Chronic Lymphocytic Leukemia

1999 • 2,674 citations

Ig V Gene Mutation Status and CD38 Expression As Novel Prognostic Indicators in Chronic Lymphocytic Leukemia

1999 • 2,557 citations

Cellular roles of DNA topoisomerases: a molecular perspective

2002 • 2,232 citations

PUMA, a Novel Proapoptotic Gene, Is Induced by p53

2001 • 2,226 citations

Death and anti-death: tumour resistance to apoptosis

2002 • 1,963 citations

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

2002 • 1,959 citations

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

2002 • 1,325 citations

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

2002 • 1,112 citations

Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

2001 • 1,110 citations

Gene Expression Profiling of B Cell Chronic Lymphocytic Leukemia Reveals a Homogeneous Phenotype Related to Memory B Cells

2001 • 934 citations

The many substrates and functions of ATM

2000 • 777 citations

Expression Profiling of Endometrium from Women with Endometriosis Reveals Candidate Genes for Disease-Based Implantation Failure and Infertility

2003 • 686 citations

Functions of LIM-homeobox genes

2000 • 474 citations

Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells

2001 • 400 citations

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

1999 • 371 citations

Proliferating cell nuclear antigen (PCNA): ringmaster of the genome

2001 • 335 citations

DNA microarrays identification of primary and secondary target genes regulated by p53

2001 • 332 citations

Relationship between p53 dysfunction, CD38 expression, andIgVH mutation in chronic lymphocytic leukemia

2002 • 252 citations

Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression

2001 • 249 citations

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative toTP53 mutation

2001 • 247 citations

ATM, a central controller of cellular responses to DNA damage

2001 • 240 citations

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

1997 • 227 citations

The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma

2001 • 224 citations

p53 Expression in B-Cell Chronic Lymphocytic Leukemia: A Marker of Disease Progression and Poor Prognosis

1998 • 175 citations

Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations.

1996 • 164 citations

Membrane Topology of the ATP Binding Cassette Transporter ABCR and Its Relationship to ABC1 and Related ABCA Transporters

2001 • 164 citations

Loss of FBP function arrests cellular proliferation and extinguishes c-myc expression

2000 • 148 citations

Ataxia telangiectasia mutated–deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage

2002 • 137 citations

Common Regulation of Apoptosis Signaling Induced by CD95 and the DNA-damaging Stimuli Etoposide and γ-Radiation Downstream from Caspase-8 Activation

1999 • 114 citations

RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human

2000 • 110 citations

Genomic instability and the role of p53 mutations in cancer cells

1995 • 109 citations

The resistance of B-CLL cells to DNA damage-induced apoptosis defined by DNA microarrays

2003 • 95 citations

A 16-kDa Protein Functions as a New Regulatory Protein for Hsc70 Molecular Chaperone and Is Identified as a Member of the Nm23/Nucleoside Diphosphate Kinase Family

1997 • 90 citations

A potential role of heat shock proteins and nicotinamide N‐methyl transferase in predicting response to radiation in bladder cancer

2002 • 88 citations

NF-κB signaling pathway as a target for human tumor radiosensitization

2001 • 85 citations

Biology of Chronic Lymphocytic Leukemia

2000 • 76 citations

Regulation of cellular functions by nucleoside diphosphate kinases in mammals.

2000 • 70 citations

Review: The Role of IRF-4 in Transcriptional Regulation

2002 • 66 citations

mRNA export: Travelling with DEAD box proteins

2001 • 65 citations

Orphan nuclear receptors in T lymphocyte development

2002 • 62 citations

Fibroblast Growth Factor Receptor 4 Is a Target for the Zinc-Finger Transcription Factor Ikaros in the Pituitary

2002 • 39 citations

Adenovirus-mediated antisense ATM gene transfer sensitizes prostate cancer cells to radiation

2000 • 39 citations

Gene transfer of the Caenorhabditis elegans n‐3 fatty acid desaturase inhibits neuronal apoptosis

2002 • 36 citations

Characterization of Human Alpha-Dystrobrevin Isoforms in HL-60 Human Promyelocytic Leukemia Cells Undergoing Granulocytic Differentiation

2002 • 26 citations

S-phase-specific expression of the Mad3 gene in proliferating and differentiating cells

2001 • 24 citations

Effects of DNA strand breaks on transcription by RNA polymerase III: insights into the role of TFIIIB and the polarity of promoter opening

2002 • 5 citations

Deleted Work

1955 • 0 citations