The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma

A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group [see comments]

1994 • 6,495 citations

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1999 • 1,549 citations

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

1999 • 1,068 citations

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

1994 • 775 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1998 • 420 citations

Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster.

1992 • 335 citations

Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function.

1993 • 319 citations

Locking in stable states of gene expression: transcriptional control during Drosophila development

1995 • 283 citations

Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation

1999 • 219 citations

Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes

1998 • 219 citations

PcG complexes and chromatin silencing

1997 • 218 citations

C-Terminal Binding Protein Is a Transcriptional Repressor That Interacts with a Specific Class of Vertebrate Polycomb Proteins

1999 • 196 citations

RING1 Is Associated with the Polycomb Group Protein Complex and Acts as a Transcriptional Repressor

1997 • 189 citations

Growing human B lymphocytes in the CD40 system

1991 • 177 citations

Chromo-domain proteins: linking chromatin structure to epigenetic regulation

1998 • 170 citations

Stage-Specific Expression of Polycomb Group Genes in Human Bone Marrow Cells

1998 • 165 citations

Coexpression of BMI-1 and EZH2 Polycomb Group Genes in Reed-Sternberg Cells of Hodgkin’s Disease

2000 • 164 citations

Identification and Characterization of Interactions between the Vertebrate Polycomb-Group Protein BMI1 and Human Homologs of Polyhomeotic

1997 • 159 citations

A Drosophila ESC-E(Z) Protein Complex Is Distinct from Other Polycomb Group Complexes and Contains Covalently Modified ESC

2000 • 150 citations

Interaction of Vav with ENX-1, a Putative Transcriptional Regulator of Homeobox Gene Expression

1996 • 129 citations

The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution

1996 • 129 citations

RING1 Interacts with Multiple Polycomb-Group Proteins and Displays Tumorigenic Activity

1999 • 122 citations

Perturbation of B and T cell development and predisposition to lymphomagenesis in EμBmi1 transgenic mice require the Bmi1 RING finger

1997 • 121 citations

Polycomb group protein complexes: do different complexes regulate distinct target genes?

1999 • 118 citations

The Role of mel-18, a Mammalian Polycomb Group Gene, during IL-7–Dependent Proliferation of Lymphocyte Precursors

1997 • 112 citations

Interference with the Expression of a Novel Human Polycomb Protein, hPc2, Results in Cellular Transformation and Apoptosis

1997 • 112 citations

Vav Is Necessary for Prolactin-stimulated Proliferation and Is Translocated into the Nucleus of a T-cell Line

1995 • 111 citations

The Drosophila Polycomb Group proteins ESC and E(Z) bind directly to each other and co-localize at multiple chromosomal sites

1998 • 95 citations

Cutting Edge: Polycomb Gene Expression Patterns Reflect Distinct B Cell Differentiation Stages in Human Germinal Centers

2000 • 94 citations

The human EZH2 gene: genomic organisation and revised mapping in 7q35 within the critical region for malignant myeloid disorders

2000 • 89 citations

The Drosophila Polycomb Group Protein Psc Contacts ph and Pc through Specific Conserved Domains

1998 • 86 citations

Optic flow: A brain region devoted to optic flow analysis?

1998 • 66 citations

mel-18 Negatively Regulates Cell Cycle Progression upon B Cell Antigen Receptor Stimulation through a Cascade Leading to c-myc/cdc25

1998 • 64 citations

Mantle cell lymphoma proliferates upon IL-10 in the CD40 system

2000 • 49 citations

Proliferative involvement of ENX‐1, a putative human Polycomb group gene, in haematopoietic cells

2000 • 31 citations