The Nuclear Receptor Rev-erbα Is a Liver X Receptor (LXR) Target Gene Driving a Negative Feedback Loop on Select LXR-Induced Pathways in Human Macrophages

Pathogen Recognition and Innate Immunity

2006 • 11,197 citations

Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

2005 • 2,323 citations

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

2002 • 2,045 citations

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

1999 • 1,905 citations

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

2004 • 1,036 citations

Adverse Effects of Modest Sleep Restriction on Sleepiness, Performance, and Inflammatory Cytokines

2004 • 977 citations

Sterol-dependent Transactivation of theABC1 Promoter by the Liver X Receptor/Retinoid X Receptor

2000 • 962 citations

Liver X receptors as integrators of metabolic and inflammatory signaling

2006 • 906 citations

A transcription factor response element for gene expression during circadian night

2002 • 852 citations

Differential Control of Bmal1 Circadian Transcription by REV-ERB and ROR Nuclear Receptors

2005 • 685 citations

Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

2007 • 647 citations

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

2001 • 643 citations

Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells

2002 • 580 citations

LXR-Dependent Gene Expression Is Important for Macrophage Survival and the Innate Immune Response

2004 • 549 citations

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ

2007 • 525 citations

Transcriptional cross-talk, the second mode of steroid hormone receptor action

1998 • 390 citations

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit.

1989 • 316 citations

The Nuclear Receptors Peroxisome Proliferator-activated Receptor α and Rev-erbα Mediate the Species-specific Regulation of Apolipoprotein A-I Expression by Fibrates

1998 • 302 citations

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-γ: a molecular basis for priming and synergism with bacterial lipopolysaccharide

2002 • 289 citations

A Nuclear Receptor Atlas: Macrophage Activation

2005 • 237 citations

The Orphan Nuclear Receptor Rev-Erbα Is a Peroxisome Proliferator-activated Receptor (PPAR) γ Target Gene and Promotes PPARγ-induced Adipocyte Differentiation

2003 • 233 citations

Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis

2004 • 212 citations

The Monomer-Binding Orphan Receptor Rev-Erb Represses Transcription as a Dimer on a Novel Direct Repeat

1995 • 204 citations

Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation

1993 • 199 citations

Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors.

1994 • 194 citations

Identification of Rev-erbα as a physiological repressor of apoC-III gene transcription

2002 • 178 citations

Diurnal rhythmicity of human cytokine production: a dynamic disequilibrium in T helper cell type 1/T helper cell type 2 balance?

1997 • 172 citations

Circadian and Glucocorticoid Regulation of Rev-erbα Expression in Liver¹

2000 • 161 citations

The orphan receptor Rev-erbα gene is a target of the circadian clock pacemaker

2004 • 157 citations

Fibrates Increase Human REV-ERBα Expression in Liver via a Novel Peroxisome Proliferator-Activated Receptor Response Element

1999 • 141 citations

Liver X Receptor Activation Potentiates the Lipopolysaccharide Response in Human Macrophages

2007 • 129 citations

Transcriptional Regulation of Apolipoprotein A-I Gene Expression by the Nuclear Receptor RORα

1997 • 129 citations

Liver X Receptor Activation Controls Intracellular Cholesterol Trafficking and Esterification in Human Macrophages

2005 • 124 citations

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity.

1996 • 121 citations

A Carboxyl-terminal Extension of the Zinc Finger Domain Contributes to the Specificity and Polarity of Peroxisome Proliferator-activated Receptor DNA Binding

1998 • 108 citations

The Human ABCG4 Gene Is Regulated by Oxysterols and Retinoids in Monocyte-Derived Macrophages

2001 • 100 citations

LXR Activation Reduces Proinflammatory Cytokine Expression in Human CD4-Positive Lymphocytes

2006 • 99 citations

Atypical patterns of circadian clock gene expression in human peripheral blood mononuclear cells

2005 • 98 citations

Orphan Nuclear Hormone Receptor Rev-erbα Regulates the Human Apolipoprotein CIII Promoter

2002 • 79 citations

Transcriptional Regulation of Human Rev-erbα Gene Expression by the Orphan Nuclear Receptor Retinoic Acid-related Orphan Receptor α

2002 • 67 citations

Dioscorin isolated from Dioscorea alata activates TLR4-signaling pathways and induces cytokine expression in macrophages

2005 • 64 citations

Rev‐erbα upregulates NF‐κB‐responsive genes in vascular smooth muscle cells

2004 • 63 citations

The role of the orphan nuclear receptor Rev-Erbα in adipocyte differentiation and function

2005 • 50 citations

Phosphorylation of histone H3 is functionally linked to retinoic acid receptor β promoter activation

2002 • 49 citations

The innate immune response under the control of the LXR pathway

2005 • 43 citations

Aberrant expression of myosin isoforms in skeletal muscles from mice lacking therev-erbAαorphan receptor gene

2004 • 40 citations

The orphan nuclear receptor Rev-erbα: a transcriptional link between circadian rhythmicity and cardiometabolic disease

2007 • 38 citations

Modulation of the Far-Upstream Enhancer of the Rat α-Fetoprotein Gene by Members of the RORα, Rev-erbα, and Rev-erbβ Groups of Monomeric Orphan Nuclear Receptors

2000 • 37 citations

Toll-like receptor 4 siRNA attenuates LPS-induced secretion of inflammatory cytokines and chemokines by macrophages

2007 • 34 citations

Genomic structure, promoter analysis and expression of the porcine (Sus scrofa) TLR4 gene

2005 • 33 citations

Orphan Nuclear Hormone Receptor RevErbα Modulates Expression from the Promoter of the Hydratase-dehydrogenase Gene by Inhibiting Peroxisome Proliferator-activated Receptor α-Dependent Transactivation

1999 • 33 citations

Orphan Nuclear Receptors, Molecular Clockwork, and the Entrainment of Peripheral Oscillators

2003 • 25 citations

Deleted Work

1955 • 0 citations