The Mammalian Brain High-Affinity l-Proline Transporter Is Enriched Preferentially in Synaptic Vesicles in a Subpopulation of Excitatory Nerve Terminals in Rat Forebrain

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY

1963 • 24,942 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.

1986 • 2,118 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

Glutamate: A Neurotransmitter in Mammalian Brain

1984 • 1,981 citations

The Fine Structure of the Nervous System.

1970 • 1,971 citations

Localization of neuronal and glial glutamate transporters

1994 • 1,668 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

1983 • 1,162 citations

Role of amino acid transport and countertransport in nutrition and metabolism.

1990 • 1,101 citations

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

Anatomical organization of excitatory amino acid receptors and their pathways

1987 • 877 citations

Cloning and Expression of a Rat Brain GABA Transporter

1990 • 873 citations

Identification and characterization of the vesicular GABA transporter

1997 • 860 citations

Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.

1985 • 716 citations

Identification of a novel gene encoding an insulin-responsive glucose transporter protein

1989 • 601 citations

A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter

1992 • 594 citations

Proteins of synaptic vesicles involved in exocytosis and membrane recycling

1991 • 523 citations

Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.

1992 • 467 citations

From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters

1993 • 461 citations

Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.

1995 • 455 citations

Optimization of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embedding

1990 • 450 citations

SODIUM‐DEPENDENT, HIGH AFFINITY CHOLINE UPTAKE

1978 • 420 citations

Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus.

1994 • 383 citations

Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression

1997 • 377 citations

Vesicle hypothesis of the release of quanta of acetylcholine.

1980 • 364 citations

The Caenorhabditis elegans unc-17 Gene: a Putative Vesicular Acetylcholine Transporter

1993 • 361 citations

The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling.

1995 • 338 citations

Storage and release of neurotransmitters

1993 • 324 citations

Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling.

1992 • 321 citations

THE ROLE OF VESICULAR TRANSPORT PROTEINS IN SYNAPTIC TRANSMISSION AND NEURAL DEGENERATION

1997 • 297 citations

Multiple Signaling Pathways Regulate Cell Surface Expression and Activity of the Excitatory Amino Acid Carrier 1 Subtype of Glu Transporter in C6 Glioma

1998 • 292 citations

Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra

1997 • 290 citations

Molecular cloning and expression of a high affinity l -proline transporter expressed in putative glutamatergic pathways of rat brain

1992 • 239 citations

Amino acid neurotransmission: spotlight on synaptic vesicles

1990 • 237 citations

Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans.

1991 • 231 citations

The preparation and characterization of synaptic vesicles of high purity

1976 • 221 citations

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.

1994 • 211 citations

Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.

1994 • 209 citations

Molecular cloning of a putative vesicular transporter for acetylcholine.

1994 • 183 citations

Constitutive and regulated membrane expression of aquaporin 1 and aquaporin 2 water channels in stably transfected LLC-PK1 epithelial cells.

1995 • 173 citations

Electron Microscopic Preembedding Double-Immunostaining Methods

1989 • 168 citations

Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells.

1993 • 167 citations

Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.

1994 • 160 citations

Synaptic structure and function: Dynamic organization yields architectural precision

1995 • 156 citations

Transmembrane Topography and Evolutionary Conservation of Synaptophysin

1989 • 153 citations

Amino Acid Neurotransmitter Candidates: Sodium-Dependent High-Affinity Uptake by Unique Synaptosomal Fractions

1972 • 144 citations

Glial cells transform glucose to alanine, which fuels the neurons in the honeybee retina

1994 • 143 citations

Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes.

1992 • 141 citations

Second Messengers, Trafficking-Related Proteins, and Amino Acid Residues that Contribute to the Functional Regulation of the Rat Brain GABA Transporter GAT1

1997 • 140 citations

Activation of Proton Pumping in Human Neutrophils Occurs by Exocytosis of Vesicles Bearing Vacuolar-type H+-ATPases

1996 • 131 citations

CHARACTERISTICS OF AMINO ACID ACCUMULATION BY SYNAPTOSOMAL PARTICLES ISOLATED FROM RAT BRAIN

1972 • 120 citations

Activation of high-affinity choline uptake in vitro by depolarizing agents.

1976 • 114 citations

Distribution of glutamate-like immunoreactivity in excitatory hippocampal pathways: A semiquantitative electron microscopic study in rats

1990 • 107 citations

The axonal gamma-aminobutyric acid transporter GAT-1 is sorted to the apical membranes of polarized epithelial cells.

1994 • 99 citations

Proline-induced potentiation of glutamate transmission

1997 • 98 citations

Structure of synaptogyrin (p29) defines novel synaptic vesicle protein.

1995 • 86 citations

Substrate specificity of the intestinal brush-border proline/sodium (IMINO) transporter

1985 • 84 citations

L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons.

1992 • 80 citations

The sluggish-A gene of Drosophila melanogaster is expressed in the nervous system and encodes proline oxidase, a mitochondrial enzyme involved in glutamate biosynthesis.

1993 • 77 citations

Transport of L-proline by rat brain slices

1976 • 74 citations

Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes.

1995 • 73 citations

[46] Multiple antigenic peptide method for producing antipeptide site-specific antibodies

1989 • 66 citations

Rapid in vitro modulation of [3H]hemicholinium-3 binding sites in rat striatal slices

1987 • 66 citations

Excitatory Amino Acid Pathways in the Brain

1986 • 57 citations

Ion-coupled neurotransmitter transport

1989 • 54 citations

Mammalian Brain-specific L-Proline Transporter.

1995 • 47 citations

Sodium‐Dependent Proline Uptake in the Rat Hippocampal Formation: Association with Ipsilateral‐Commissural Projections of CA3 Pyramidal

1987 • 40 citations

Autoradiographic localization of proline uptake in excitatory hippocampal pathways

1992 • 38 citations

Proline, glutamate and glutamine metabolism in mouse brain synaptosomes

1984 • 34 citations

Cloned Sodium- (and Chloride-) Dependent High-Affinity Transporters for GABA, Glycine, Proline, Betaine, Taurine, and Creatine

1997 • 31 citations

Molecular characterization of neurotransmitter transporters.

1993 • 31 citations

A novel nonopioid action of enkephalins: competitive inhibition of the mammalian brain high affinity L-proline transporter.

1996 • 31 citations

A Mammalian Activity Required for the Second Step of Pre-messenger RNA Splicing

1995 • 29 citations

Molecular characterization of neurotransmitter transporters

1993 • 13 citations