Chronic lymphocytic leukaemia and its relationship to normal B lymphopoiesis

Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin.

1980 • 429 citations

Terminal Deoxynucleotidyl Transferase Activity in Human Leukemic Cells and in Normal Human Thymocytes

1975 • 371 citations

ISOLATION OF NORMAL T CELLS IN CHRONIC LYMPHATIC LEUKÆMIA

1973 • 335 citations

In vitro tolerance induction of neonatal murine B cells.

1976 • 281 citations

B-CELL NEOPLASIA IN MAN

1974 • 271 citations

Analysis of the clinical and biological significance of lymphoid phenotypes in acute leukemia.

1981 • 224 citations

A monoclonal antibody defining antigenic determinants on subpopulations of mammalian neurones and Trypanosoma cruzi parasites

1982 • 222 citations

Human T Lymphocyte Antigens as Defined by Monoclonal Antibodies

1981 • 214 citations

The characterization and function of human immunoregulatory T lymphocyte subsets

1981 • 205 citations

Humoral and Cellular Immunity in Humans Studied at the Cell Level from Birth to Two Years of Age

1981 • 181 citations

Abnormal T-cell subpopulation function in CLL: excessive suppressor (T gamma) and deficient helper (T mu) activity with respect to B-cell proliferation

1981 • 168 citations

Heterogeneity of B-cell leukemias demonstrated by the monoclonal antibody FMC7

1981 • 146 citations

Mouse Red‐Cell Rosettes in B‐Lymphoproliferative Disorders

1976 • 141 citations

Studies on the lymphocyte 5'-nucleotidase in chronic lymphocytic leukemia, infectious mononucleosis, normal subpopulations, and phytohemagglutinin-stimulated cells.

1974 • 137 citations

Some chronic lymphocytic leukemia cells bearing surface immunoglobulins share determinants with T cells

1978 • 136 citations

A Distinctive Pattern of B Cell Immaturity in Perinatal Humans

1981 • 133 citations

Differentiation Capacity and Other Properties of the Leukemic Cells of Chronic Lymphocytic Leukemia*

1979 • 102 citations

Maturation of B‐Cell Differentiation Ability and T‐Cell Regulatory Function in Infancy and Childhood

1981 • 100 citations

Extracellular idiotypic immunoglobulin arising from human leukemic B lymphocytes.

1980 • 89 citations

Development of B lymphocytes. I. Cell populations and a critical event during ontogeny.

1975 • 85 citations

Unusual T‐Cell Phenotype in Advanced B‐Chronic Lymphocytic Leukaemia

1981 • 83 citations

A subpopulation of human B lymphocytes that rosette with mouse erythrocytes.

1976 • 77 citations

Mitogen activation of human chronic lymphatic leukemia cells. I. Synthesis and secretion of immunoglobulin.

1977 • 67 citations

Diversity of immunoglobulin expression in leukaemic cells resembling B-lymphocyte precursors

1981 • 60 citations

Hypogammaglobulinaemia associated with abnormalities of both B and T lymphocytes in patients with chronic lymphatic leukaemia.

1980 • 60 citations

Lymphocyte 5'-nucleotidase in primary hypogammaglobulinaemia and cord blood.

1980 • 58 citations

Receptors for Helix pomatia A haemagglutinin on leukaemic lymphocytes from patients with chronic lymphocytic leukaemia (CLL).

1976 • 55 citations

Surface IgD in Immunoproliferative Disorders

1974 • 55 citations

Generation of immunoglobulin variable gene diversity

1982 • 52 citations

The organization and expression of immunoglobulin genes

1980 • 51 citations

Receptors for Helix pomatia A Haemagglutinin (HP) on a Subpopulation of Human B Cells

1978 • 50 citations

Free immunoglobulin light chain synthesis by human foetal liver and cord blood lymphocytes.

1981 • 48 citations

Monoclonal antibody against a membrane antigen characterizing leukemic human B-lymphocytes.

1982 • 48 citations

IgA and IgM cytoplastic inclusions in a series of cases of chronic lymphocytic leukaemia.

1976 • 47 citations

Cell surface glycoprotein analysis: A diagnostic tool in human leukemias

1979 • 45 citations

The presence of monoclonal cytoplasmic immunoglobulins in leukemic B cells from patients with chronic lymphocytic leukemia

1982 • 45 citations

Differences in the Behavior of the Membrane and Membrane-Associated Filamentous Structures in Normal and Chronic Lymphocytic Leukemia (CLL) Lymphocytes

1979 • 44 citations

Mitogen‐induced Differentiation of Human CLL Lymphocytes to Antibody‐secreting Cells

1979 • 44 citations

Development of B Lymphocytes

1975 • 43 citations

Lymphocyte surface immunoglobulin density and immunoglobulin secretion in vitro in chronic lymphocytic leukemia (CLL)

1978 • 37 citations

The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia.

1981 • 33 citations

Mitogen-stimulated immunoglobulin production by chronic lymphocytic leukaemic lymphocytes.

1982 • 30 citations

Mitogen Activation of Human Chronic Lymphatic Leukemia Cells

1977 • 29 citations

Killing and Characterizing Action of Colchicine in vitro on Lymphocytes of Chronic Lymphocytic Leukaemia

1972 • 28 citations

Human lymphocyte markers defined by antibodies derived from somatic cell hybrids. III. A marker defining a subpopulation of lymphocytes which cuts across the normal T-B-null classification.

1980 • 20 citations

Immunoglobulin Expression in Human Lymphoblastoid Cell Lines with Early B Cell Features

1981 • 17 citations

Chemical bursectomy of chickens with colchicine applied to the anal lips.

1980 • 15 citations

Induction of balanced immunoglobulin chain synthesis in free light chain-producing lymphocytes by mitogen stimulation.

1981 • 13 citations

The roles of leukaemic and residual normal cells in the proliferative response of chronic lymphocytic leukaemic lymphocytes to mitogens.

1982 • 5 citations