Toll-Like Receptor 4-Dependent Activation of Dendritic Cells by β-Defensin 2

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

2001 • 1,845 citations

β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6

1999 • 1,760 citations

Innate Immunity

2000 • 1,715 citations

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

2000 • 1,632 citations

Innate immunity: impact on the adaptive immune response

1997 • 1,542 citations

HSP70 as Endogenous Stimulus of the Toll/Interleukin-1 Receptor Signal Pathway

2002 • 949 citations

Endotoxin signal transduction in macrophages

1996 • 803 citations

TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages

2002 • 802 citations

An innate sense of danger

1998 • 752 citations

Lipopolysaccharide Is in Close Proximity to Each of the Proteins in Its Membrane Receptor Complex

2001 • 652 citations

Toll-like Receptor 4 Resides in the Golgi Apparatus and Colocalizes with Internalized Lipopolysaccharide in Intestinal Epithelial Cells

2002 • 414 citations

Mediators of Innate Immunity That Target Immature, But Not Mature, Dendritic Cells Induce Antitumor Immunity When Genetically Fused with Nonimmunogenic Tumor Antigens

2001 • 280 citations

Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity

1999 • 278 citations

β-Defensins in Lung Host Defense

2002 • 256 citations

Molecular Mechanisms of Polymyxin B-Membrane Interactions: Direct Correlation Between Surface Charge Density and Self-Promoted Transport

1998 • 128 citations

DNA vaccines encoding human immunodeficiency virus–1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responses

2002 • 125 citations

NF-kappa B-mediated transcriptional regulation of human beta-defensin-2 gene following lipopolysaccharide stimulation.

2002 • 121 citations

NF-κB-mediated transcriptional regulation of human β-defensin-2 gene following lipopolysaccharide stimulation

2002 • 101 citations

Diphosphoryl lipid A from Rhodobacter sphaeroides inhibits complexes that form in vitro between lipopolysaccharide (LPS)-binding protein, soluble CD14, and spectrally pure LPS

1997 • 36 citations