Human myelin basic protein-specific cytolytic T lymphocyte clones are functionally restricted by HLA class II gene products

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Large Scale Preparation of Myelin Basic Protein from Central Nervous Tissue of Several Mammalian Species

1972 • 949 citations

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

1982 • 877 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Treatment of multiple sclerosis with gamma interferon

1987 • 739 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon.

1983 • 638 citations

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

1985 • 522 citations

T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

1986 • 471 citations

Multiple Sclerosis: Distribution of T Cell Subsets Within Active Chronic Lesions

1983 • 417 citations

Measles Encephalomyelitis — Clinical and Immunologic Studies

1984 • 404 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

Multiple sclerosis☆Distribution of T cells, T cell subsets and Ia-positive macrophages in lesions of different ages

1983 • 309 citations

Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells.

1982 • 261 citations

The Major Histocompatibility Complex — Genetics and Biology

1976 • 226 citations

Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes

1986 • 214 citations

Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens.

1984 • 209 citations

The Major Histocompatibility Complex — Genetics and Biology

1976 • 196 citations

Myelin Basic Protein as an Encephalitogen in Encephalomyelitis and Polyneuritis Following Rabies Vaccination

1987 • 175 citations

Multiple sclerosis: relevance of Class I and Class II MHC-expressing cells to lesion development

1987 • 169 citations

Encephalitogenic T cell clones specific for myelin basic protein. An unusual bias in antigen recognition.

1985 • 147 citations

Presentation of myelin basic protein by murine cerebral vascular endothelial cells.

1985 • 129 citations

Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis.

1987 • 127 citations

Specificity of T lymphocyte lines for peptides of myelin basic protein.

1985 • 125 citations

Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis.

1985 • 122 citations

Human disease: Mechanisms in multiple sclerosis

1985 • 100 citations

Neuroimmunology I: Immunoregulation in neurological disease

1982 • 99 citations

A mouse monoclonal antibody detecting a DR-related MT2-like specificity: Serology and biochemistry

1984 • 97 citations

Human T4+ and T8+ cytotoxic T lymphocyte clones directed at products of different class II major histocompatibility complex loci.

1983 • 87 citations

Experimental autoimmune encephalomyelitis mediated by T lymphocyte lines: genotype of antigen-presenting cells influences immunodominant epitope of basic protein.

1986 • 79 citations

The Major Histocompatibility Complex — Genetics and Biology

1976 • 79 citations

Controlled‐release levodopa/carbidopa.

1987 • 66 citations

T cell specificity for class II (I-A) and the encephalitogenic N-terminal epitope of the autoantigen myelin basic protein.

1987 • 52 citations

Influenza virus-specific cytotoxic T lymphocytes recognize HLA-molecules. Blocking by monoclonal anti-HLA antibodies.

1980 • 51 citations

Activation through CD3 molecule leads to clonal expansion of all human peripheral blood T lymphocytes: functional analysis of clonally expanded cells.

1985 • 51 citations

Cytolytic activity of antigen-specific T cells with helper phenotype.

1986 • 50 citations

The significance of abnormal immune responses in patients with multiple sclerosis

1981 • 41 citations

Cellular hypersensitivity in attacks of multiple sclerosis

1977 • 38 citations

Cytomegalovirus encephalitis associated with episodic neurologic deficits and OKT‐8 ⁺ pleocytosis

1987 • 36 citations

Dissection of human allostimulatory determinants with cloned T cells: Stimulation inhibition by monoclonal antibodies TÜ22, 34, 36, 37, 39, 43, and 58 against distinct human MHC class II molecules

1985 • 35 citations

Cellular hypersensitivity to gangliosides and myelin basic protein in multiple sclerosis

1983 • 32 citations

Myelin basic protein-specific CD4+ cytolytic T-lymphocyte clones isolated from multiple sclerosis patients

1988 • 27 citations

Fine analysis of cytolytic and natural killer T lymphocytes in the CSF in multiple sclerosis and other neurologic diseases

1987 • 19 citations

Lymphocyte responsiveness to oligodendrocytes in multiple sclerosis

1981 • 11 citations

Human T cell response to myelin basic protein: Is the T cell repertoire different in multiple sclerosis patients and healthy subjects?

1987 • 2 citations

Antibody Cross‐Reactivity Between Myelin Basic Protein and CD3 Antigen of T Cells Implications for Autoimmunity

1988 • 2 citations