ProSAP/Shank proteins – a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

PDZ Domains and the Organization of Supramolecular Complexes

2001 • 1,203 citations

Proteomic analysis of NMDA receptor–adhesion protein signaling complexes

2000 • 1,201 citations

Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics

1989 • 1,069 citations

Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins

1999 • 1,024 citations

Shank, a Novel Family of Postsynaptic Density Proteins that Binds to the NMDA Receptor/PSD-95/GKAP Complex and Cortactin

1999 • 980 citations

A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity

1996 • 948 citations

Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

1998 • 852 citations

Signal-Processing Machines at the Postsynaptic Density

2000 • 792 citations

Regulation of Dendritic Spine Morphology and Synaptic Function by Shank and Homer

2001 • 685 citations

Protein Synthesis at Synaptic Sites on Dendrites

2001 • 682 citations

Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus

1982 • 665 citations

The Shank family of scaffold proteins

2000 • 555 citations

PDZ domains in synapse assembly and signalling

2000 • 525 citations

Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.

1993 • 510 citations

The detection of subtelomeric chromosomal rearrangements in idiopathic mental retardation

1995 • 510 citations

GKAP, a Novel Synaptic Protein That Interacts with the Guanylate Kinase-like Domain of the PSD-95/SAP90 Family of Channel Clustering Molecules

1997 • 503 citations

Dynamin-dependent endocytosis of ionotropic glutamate receptors

1999 • 425 citations

SAP97 Is Associated with the α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor GluR1 Subunit

1998 • 415 citations

Enlightening the Postsynaptic Density

1997 • 381 citations

SAPAPs

1997 • 356 citations

Disruption of the ProSAP2 Gene in a t(12;22)(q24.1;q13.3) Is Associated with the 22q13.3 Deletion Syndrome

2001 • 290 citations

Laminar Organization of the NMDA Receptor Complex within the Postsynaptic Density

2001 • 290 citations

Characterization of the Shank Family of Synaptic Proteins

1999 • 273 citations

Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons

1998 • 257 citations

Proline-Rich Synapse-Associated Protein-1/Cortactin Binding Protein 1 (ProSAP1/CortBP1) Is a PDZ-Domain Protein Highly Enriched in the Postsynaptic Density

1999 • 243 citations

Identification of fodrin as a major calmodulin-binding protein in postsynaptic density preparations.

1983 • 205 citations

Proline-Rich Synapse-Associated Proteins ProSAP1 and ProSAP2 Interact with Synaptic Proteins of the SAPAP/GKAP Family

1999 • 192 citations

Marking synaptic activity in dendritic spines with a calpain substrate exhibiting fluorescence resonance energy transfer

2000 • 163 citations

Sharpin, a Novel Postsynaptic Density Protein That Directly Interacts with the Shank Family of Proteins

2001 • 150 citations

Somatostatin Receptor Interacting Protein Defines a Novel Family of Multidomain Proteins Present in Human and Rodent Brain

1999 • 141 citations

Synaptic Scaffolding Proteins in Rat Brain

2001 • 138 citations

Molecular characterization of a 130-kb terminal microdeletion at 22q in a child with mild mental retardation.

1997 • 136 citations

Calmodulin and calcium-dependent protease I coordinately regulate the interaction of fodrin with actin.

1990 • 131 citations

Clinical, cytogenetic, and molecular characterization of seven patients with deletions of chromosome 22q13.3.

1994 • 123 citations

Genetic evaluation of pervasive developmental disorders: the terminal 22q13 deletion syndrome may represent a recognizable phenotype

2000 • 100 citations

Synamon, a Novel Neuronal Protein Interacting with Synapse-associated Protein 90/Postsynaptic Density-95-associated Protein

1999 • 96 citations

A familial pericentric inversion of chromosome 22 with a recombinant subject illustrating a 'pure' partial monosomy syndrome.

1985 • 85 citations

Dynamin Isoform-specific Interaction with the Shank/ProSAP Scaffolding Proteins of the Postsynaptic Density and Actin Cytoskeleton

2001 • 84 citations

The Calcium-independent Receptor for α-Latrotoxin from Human and Rodent Brains Interacts with Members of the ProSAP/SSTRIP/Shank Family of Multidomain Proteins

2000 • 80 citations

The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family

2000 • 77 citations

Agonist-dependent Interaction of the Rat Somatostatin Receptor Subtype 2 with Cortactin-binding Protein 1

1999 • 71 citations

Sema4C, a Transmembrane Semaphorin, Interacts with a Post-synaptic Density Protein, PSD-95

2001 • 62 citations

Semaphorin4F interacts with the synapse‐associated protein SAP90/PSD‐95

2001 • 43 citations

Molecular organization of excitatory chemical synapses in the mammalian brain

2000 • 25 citations

The Cortactin-binding Postsynaptic Density Protein ProSAP1 in Non-neuronal Cells

2001 • 24 citations