Identification of α1-Antitrypsin Variants in Plasma with the Use of Proteomic Technology

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Biological roles of oligosaccharides: all of the theories are correct

1993 • 5,121 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

High resolution two-dimensional electrophoresis of human plasma proteins.

1977 • 659 citations

Methods for increasing the resolution of two-dimensional protein electrophoresis

1988 • 650 citations

α1-antitrypsin deficiency

2005 • 631 citations

Molecular basis of alpha-1-antitrypsin deficiency

1988 • 505 citations

Pulmonary Emphysema and Alpha₁‐Antitrypsin Deficiency

1964 • 465 citations

A nonlinear wide‐range immobilized pH gradient for two‐dimensional electrophoresis and its definition in a relevant pH scale

1993 • 386 citations

Development of polyacrylamide gels that improve the separation of proteins and their detection by silver staining

1988 • 305 citations

The polymorphism of “prealbumins” and α1-antitrypsin in human sera

1967 • 283 citations

Analysis of Acidic Oligosaccharides and Glycopeptides by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

1996 • 281 citations

Plasma protein map: An update by microsequencing

1992 • 135 citations

α1-antitrypsin microheterogeneity

1982 • 100 citations

Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders

1998 • 81 citations

Highly enhanced fucosylation of serum glycoproteins in patients with hepatocellular carcinoma

1999 • 80 citations

Structural and functional characterization of the abnormal Z α₁‐antitrypsin isolated from human liver

1984 • 76 citations

Carbohydrate-Deficient Glycoprotein Syndromes: Inborn Errors of Protein Glycosylation

1999 • 73 citations

Proteome Analysis: Genomics via the Output Rather Than the Input Code

1997 • 65 citations

Diseases of the liver and biliary system. 9th ed

1993 • 63 citations

Structural determination ofN-linked carbohydrates by matrix-assisted laser desorption/ionization-mass spectrometry following enzymatic release within sodium dodecyl sulphate-polyacrylamide electrophoresis gels: Application to species-specific glycosylation of α1-acid glycoprotein

1998 • 60 citations

'Catalysts' for polyacrylamide gel polymerization and detection of proteins by silver staining.

1988 • 60 citations

Folding Pathway of Human α1-Antitrypsin: Characterization of an Intermediate That Is Active but Prone to Aggregation

1996 • 58 citations

Isolation and characterization of two minor fractions of α1,-antitrypsin by high-performance liquid chromatographic chromatofocusing

1985 • 41 citations

Proteomics and molecular medicine

1999 • 36 citations

Disruption of the Lys‐290‐Glu‐342 salt bridge in human α₁‐antitrypsin does not prevent its synthesis and secretion

1987 • 35 citations

A strategy for the identification of site-specific glycosylation in glycoproteins using MALDI TOF MS

2000 • 22 citations

The Effects of Reactive Centre Loop Length upon Serpin Polymerisation

1997 • 17 citations

A new alpha 1‐antitrypsin mutation, Thr–Met 85, (PI Z_bristol) associated with novel electrophoretic properties

1997 • 15 citations

Plasma Protease Inhibitors in α1-Antitrypsin-Deficient Children

1985 • 14 citations