Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells
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References (49)
Dendritic cells and the control of immunity
1998 • 14,345 citations
Immunobiology of Dendritic Cells
2000 • 6,653 citations
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 • 6,443 citations
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
1999 • 5,659 citations
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
1994 • 5,204 citations
Cellular survival: a play in three Akts
1999 • 4,229 citations
NF-κB at the crossroads of life and death
2002 • 2,684 citations
CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs
1999 • 2,326 citations
Proliferating dendritic cell progenitors in human blood.
1994 • 1,922 citations
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 • 1,897 citations
Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence
1995 • 923 citations
The Regulation and Activities of the Multifunctional Serine/Threonine Kinase Akt/PKB
1999 • 882 citations
Constitutive class I-restricted exogenous presentation of self antigens in vivo.
1996 • 637 citations
Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.
1998 • 627 citations
Dancing to the tune of chemokines
2001 • 624 citations
Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma Invasion
1997 • 615 citations
In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells
1997 • 560 citations
Understanding dendritic cell and T‐lymphocyte traffic through the analysis of chemokine receptor expression
2000 • 526 citations
The NF-κB Activation Pathway: A Paradigm in Information Transfer from Membrane to Nucleus
1999 • 485 citations
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
1999 • 475 citations
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
2002 • 443 citations
Activation of the JNK signaling pathway: Breaking the brake on apoptosis
2002 • 432 citations
Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals.
2001 • 425 citations
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.
1994 • 414 citations
Dendritic Cell Development and Survival Require Distinct NF-κB Subunits
2002 • 395 citations
Protein Kinase B Regulates T Lymphocyte Survival, Nuclear Factor κb Activation, and Bcl-XL Levels in Vivo
2000 • 339 citations
Modulation of NF-κB Activity by Exchange of Dimers
2003 • 297 citations
DC-SIGN (CD209) Expression Is IL-4 Dependent and Is Negatively Regulated by IFN, TGF-β, and Anti-Inflammatory Agents
2002 • 291 citations
The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3 beta are potent chemoattractants for in vitro- and in vivo-derived dendritic cells.
1999 • 251 citations
Signal Transduction by Cxc Chemokine Receptor 4
2000 • 222 citations
Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators
2001 • 210 citations
Extracellular signal–regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells
2001 • 207 citations
Expression of the Serpin Serine Protease Inhibitor 6 Protects Dendritic Cells from Cytotoxic T Lymphocyte–Induced Apoptosis
2001 • 205 citations
The p42/p44 MAP Kinase Pathway Prevents Apoptosis Induced by Anchorage and Serum Removal
2000 • 179 citations
N‐Acetylcysteine suppresses TNF‐induced NF‐κB activation through inhibition of IκB kinases
2000 • 172 citations
Genetic tagging shows increased frequency and longevity of antigen-presenting, skin-derived dendritic cells in vivo
2003 • 128 citations
Leukocyte migration: Scent of the T zone
2000 • 116 citations
CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities
2003 • 106 citations
CCL19 induces rapid dendritic extension of murine dendritic cells
2002 • 104 citations
Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand–mediated apoptosis
2000 • 92 citations
CCR7-mediated physiological lymphocyte homing involves activation of a tyrosine kinase pathway
2002 • 92 citations
Dynamics of NF κB and IκBα Studied with Green Fluorescent Protein (GFP) Fusion Proteins
2000 • 84 citations
The Interaction of Activated Integrin Lymphocyte Function-associated Antigen 1 with Ligand Intercellular Adhesion Molecule 1 Induces Activation and Redistribution of Focal Adhesion Kinase and Proline-rich Tyrosine Kinase 2 in T Lymphocytes
1999 • 83 citations
Rho kinase is required for CCR7‐mediated polarization and chemotaxis of T lymphocytes
2003 • 73 citations
Rho and Rho-associated Kinase Modulate the Tyrosine Kinase PYK2 in T-cells through Regulation of the Activity of the Integrin LFA-1
2001 • 63 citations
The Regulation and Activities of the Multifunctional Serine/Threonine Kinase Akt/PKB
2000 • 32 citations
An octamer element functions as a regulatory element in the differentiation-responsive CD11c integrin gene promoter: OCT-2 inducibility during myelomonocytic differentiation.
1997 • 26 citations
The neuronal protein Kidins220 localizes in a raft compartment at the leading edge of motile immature dendritic cells
2003 • 24 citations
Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand–mediated apoptosis
2000 • 15 citations
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