Clinical symptoms and DNA repair characteristics of xeroderma pigmentosum patients from Germany.

DNA Repair Enzymes

1982 • 905 citations

Fractionation of DNA from mammalian cells by alkaline elution

1976 • 838 citations

Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.

1975 • 617 citations

EVIDENCE THAT XERODERMA PIGMENTOSUM CELLS DO NOT PERFORM THE FIRST STEP IN THE REPAIR OF ULTRAVIOLET DAMAGE TO THEIR DNA

1969 • 472 citations

Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts

1988 • 448 citations

XERODERMA PIGMENTOSUM: A HUMAN DISEASE IN WHICH AN INITIAL STAGE OF DNA REPAIR IS DEFECTIVE

1969 • 417 citations

Xeroderma Pigmentosum Group E Cells Lack a Nuclear Factor That Binds to Damaged DNA

1988 • 417 citations

Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

1968 • 378 citations

8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution^*

1967 • 335 citations

Xeroderma pigmentosum neurological abnormalities correlate with colony-forming ability after ultraviolet radiation.

1978 • 257 citations

Xeroderma Pigmentosum: Variants with Normal Dna Repair and Normal Sensitivity to Ultraviolet Light

1972 • 244 citations

Human Diseases Associated with Defective DNA Repair

1979 • 224 citations

Five complementation groups in xeroderma pigmentosum

1975 • 199 citations

DNA single-strand breaks during repair of UV damage in human fibroblasts and abnormalities of repair in xeroderma pigmentosum.

1976 • 176 citations

National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014, USA.

1975 • 170 citations

Nucleosome structure controls rates of excision repair in DNA of human cells

1977 • 124 citations

Characterization of a splicing mutation in group A xeroderma pigmentosum.

1990 • 123 citations

DNA repair characteristics and skin cancers of xeroderma pigmentosum patients in Japan.

1977 • 121 citations

A sixth complementation group in xeroderma pigmentosum

1979 • 119 citations

Molecular genetics of eukaryotic DNA excision repair.

1990 • 99 citations

High sensitivity of xeroderma pigmentosum cells to the carcinogen 4-nitroquinoline-1-oxide

1972 • 91 citations

Xeroderma pigmentosum. Defective DNA repair causes skin cancer and neurodegeneration

1988 • 91 citations

Reduced DNA repair synthesis in xeroderma pigmentosum cells exposed to the oncogenic 4-nitroquinoline 1-oxide and 4-hydroxy-aminoquinoline 1-oxide

1971 • 79 citations

Cyclobutane-type pyrimidine photodimer formation and excision in human skin fibroblasts after irradiation with 313-nm ultraviolet light

1983 • 73 citations

Genetics and skin cancer of xeroderma pigmentosum in Japan.

1987 • 71 citations

Defective postreplication repair in xeroderma pigmentosum variant fibroblasts.

1990 • 70 citations

Clinical characteristics, DNA repair, and complementation groups in xeroderma pigmentosum patients from Egypt.

1980 • 63 citations

Evidence that xeroderma pigmentosum cells from complementation group E are deficient in a homolog of yeast photolyase.

1989 • 62 citations

Photoreactivation of thymine dimers in UV-irradiated human cells: Unique dependence on culture conditions

1977 • 61 citations

Excision of N-acetoxy-2-acetylaminofluorene-induced DNA adducts from chromatin fractions of human fibroblasts.

1980 • 60 citations

Late onset of skin cancers in 2 xeroderma pigmentosum group F siblings and a review of 30 Japanese xeroderma pigmentosum patients in groups D, E and F.

1989 • 36 citations

Colony-forming ability of ultraviolet-irradiated xeroderma pigmentosum fibroblasts from different DNA repair complementation groups

1976 • 36 citations

Xeroderma pigmentosum patients from the federal Republic of Germany: Decrease in post-UV colony-forming ability in 30 xeroderma pigmentosum fibroblast strains is quantitatively correlated with a decrease in DNA-incising capacity

1985 • 35 citations

Xeroderma Pigmentosum Patients from Egypt: II. Preliminary Correlations of Epidemiology, Clinical Symptoms and Molecular Biology

1981 • 27 citations

DNA repair synthesis in fibroblast strains from patients with actinic keratosis, squamous cell carcinoma, basal cell carcinoma, or malignant melanoma after treatment with ultraviolet light, N-acetoxy-2-acetyl-aminofluorene, methyl methanesulfonate, and N-methyl-N-nitrosourea

1987 • 24 citations

Xeroderma pigmentosum variants

1981 • 24 citations

XP patients from Germany: Correlation of colony-forming ability, unscheduled DNA synthesis and single-strand breaks after UV damage in xeroderma pigmentosum fibroblasts

1982 • 19 citations

Heterogeneity of xeroderma pigmentosum (XP); variability and stability within and between the complementation groups C, D, E, I and variants.

1986 • 17 citations

Xeroderma pigmentosum patients from Germany: repair capacity of 45 XP fibroblast strains of the Mannheim XP Collection as measured by colony-forming ability and unscheduled DNA synthesis following treatment with methyl methanesulfonate and N-methyl-N-nitrosourea

1986 • 11 citations

Correlation of the colony-forming abilities of xeroderma pigmentosum fibroblasts with repair-specific DNA incision reactions catalyzed by cell-free extracts

1980 • 9 citations

A re-evaluation of evidence for carcinogen-induced DNA “repair” synthesis

1978 • 9 citations

Straightening out the supercoil

1978 • 9 citations

Photoreactivation in Bacteria and in Skin

1981 • 8 citations

Comparison of DNA-incising capacities in fibroblast strains from the Mannheim XP collection after treatment with N-acetoxy-2-acetylaminofluorene and UV light

1988 • 7 citations

Computational statistics for cell survival curves. I. Evaluation of the colony-forming ability of a single cell strain by the APL function CFALINE

1985 • 6 citations

Computational statistics for cell survival curves. II. Evaluation of colony-forming ability of a group of cell strains by the APL function CFAGROUP

1985 • 6 citations

Analysis of Colony‐Forming Ability of Human Fibroblast Strains by Linear Regression

1987 • 5 citations