Changing responsiveness of developing midbrain dopaminergic neurons for extracellular growth factors

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

1991 • 1,487 citations

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1990 • 1,238 citations

Characterization of a multicomponent receptor for GDNF

1996 • 1,086 citations

Functional receptor for GDNF encoded by the c-ret proto-oncogene

1996 • 795 citations

The neurotrophic factor concept: a reexamination

1993 • 745 citations

Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat. I. Cell differentiation

1974 • 653 citations

Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3.

1991 • 610 citations

Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system

1992 • 592 citations

Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II

1990 • 529 citations

The pre- and postnatal development of the dopaminergic cell groups in the ventral mesencephalon and the dopaminergic innervation of the striatum of the rat

1988 • 499 citations

Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon

1994 • 374 citations

Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny

1981 • 349 citations

Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture

1989 • 318 citations

The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia [published erratum appears in J Neurosci 1992 Mar;12(3):685]

1991 • 310 citations

Sensory neurons in culture: Changing requirements for survival factors during embryonic development

1980 • 302 citations

Dopaminergic neurons in rat ventral midbrain express brain‐derived neurotrophic factor and neurotrophin‐3 mRNAs

1994 • 290 citations

Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat

1995 • 270 citations

Changes in neurotrophin responsiveness during the development of cerebellar granule neurons

1992 • 240 citations

The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)-insulin-like growth FACTOR-1, and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture

1993 • 176 citations

EGF enhances the survival of dopamine neurons in rat embryonic mesencephalon primary cell culture

1991 • 173 citations

Neuronal GDNF Expression in the Adult Rat Nervous System Identified By In Situ Hybridization

1997 • 161 citations

Conditioned media derived from glial cell lines promote survival and differentiation of dopaminergic neurons in vitro: Role of mesencephalic glia

1991 • 151 citations

Expression of acidic and basic fibroblast growth factors in the substantia nigra of rat, monkey, and human.

1991 • 139 citations

Trophic actions of transforming growth factor α on mesencephalic dopaminergic neurons developing in culture

1993 • 125 citations

Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains

1992 • 124 citations

Developmental and regional expression of basic fibroblast growth factor mRNA in the rat central nervous system

1990 • 115 citations

Expression of acidic fibroblast growth factor mRNA in the developing and adult rat brain

1991 • 113 citations

Neurotrophic‐4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures

1994 • 108 citations

Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture

1993 • 105 citations

Epidermal growth factor exerts neuronotrophic effects on dopaminergic and GABAergic CNS neurons: Comparison with basic fibroblast growth factor

1991 • 94 citations

Prenatal development of mesencephalic and diencephalic dopaminergic systems in the male and female rat

1990 • 70 citations

Effects of acidic and basic fibroblast growth factors (aFGF, bFGF) on glial precursor cell proliferation: Age dependency and brain region specificity

1992 • 66 citations

Local support cells promote survival of substantia nigra dopaminergic neurons in culture

1991 • 66 citations

Midkine, a novel neurotrophic factor, promotes survival of mesencephalic neurons in culture

1993 • 60 citations

Effects of glial cell line-derived neurotrophic factor (GDNF) on dopaminergic neurons require concurrent activation of cAMP-dependent signaling pathways

1996 • 52 citations

Growth factor-induced c-fos expression defines distinct subsets of midbrain dopaminergic neurons

1996 • 37 citations

Electrophysiology and ultrastructure of mouse hypothalamic neurons in culture: a correlative analysis during development

1988 • 28 citations

Evidence for a novel neurotrophic factor for dopaminergic neurons secreted from mesencephalic glial cell lines

1996 • 26 citations