Cross-Talk Between Iron Metabolism and Diabetes

Nonalcoholic Fatty Liver Disease

2001 • 2,567 citations

Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets

2000 • 724 citations

Circulating Interleukin 6 Levels, Blood Pressure, and Insulin Sensitivity in Apparently Healthy Men and Women

2001 • 549 citations

Insulin resistance–associated hepatic iron overload

1999 • 502 citations

Regulators of iron balance in humans [see comments]

1994 • 457 citations

Diabetes and serum ferritin concentration among U.S. adults.

1999 • 423 citations

Ferritin as a source of iron for oxidative damage

1992 • 359 citations

A new syndrome of liver iron overload with normal transferrin saturation

1997 • 343 citations

Blood Letting in High-Ferritin Type 2 Diabetes

2002 • 332 citations

Serum Ferritin as a Component of the Insulin Resistance Syndrome

1998 • 326 citations

Body Iron Stores Are Associated With Serum Insulin and Blood Glucose Concentrations: Population study in 1,013 eastern Finnish men

1997 • 321 citations

Clinical Consequences of Acquired Transfusional Iron Overload in Adults

1981 • 293 citations

Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C

2001 • 279 citations

Iron Chelation Improves Endothelial Function in Patients With Coronary Artery Disease

2001 • 273 citations

Iron, Atherosclerosis, and Ischemic Heart Disease

1999 • 258 citations

Relation between iron stores and non-insulin dependent diabetes in men: case-control study

1998 • 247 citations

Insulin stimulates cellular iron uptake and causes the redistribution of intracellular transferrin receptors to the plasma membrane.

1986 • 236 citations

Insulin Resistance and Hyperinsulinemia in Patients with Thalassemia Major Treated by Hypertransfusion

1988 • 226 citations

Association of serum ferritin and indices of body fat distribution and obesity in Mexican American men—the Third National Health and Nutrition Examination Survey

2001 • 197 citations

Major Factors in the Development of Diabetes Mellitus in 10,000 Men

1975 • 197 citations

Blood Donations and Risk of Coronary Heart Disease in Men

2001 • 193 citations

Iron Overload Augments the Development of Atherosclerotic Lesions in Rabbits

1995 • 182 citations

Hyperinsulinaemia in non-cirrhotic haemochromatosis: impaired hepatic insulin degradation?

1984 • 181 citations

Iron-Deficient Diet Reduces Atherosclerotic Lesions in ApoE-Deficient Mice

1999 • 176 citations

Mechanisms of Iron Accumulation in Hereditary Hemochromatosis

2002 • 169 citations

Dietary lean red meat and human evolution

2000 • 162 citations

Increased ferritin gene expression in atherosclerotic lesions.

1996 • 161 citations

Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with a high prevalence of elevated iron stores

2001 • 157 citations

Observations on the pathogenesis, complications and treatment of diabetes in 115 cases of haemochromatosis

1972 • 154 citations

OBESITY, VERY LOW DENSITY LIPOPROTEINS, AND GLUCOSE INTOLERANCE OVER FOURTEEN YEARS

1981 • 143 citations

Histologic Features of the Liver in Insulin Resistance–Associated Iron Overload

2001 • 137 citations

Gestational diabetes mellitus in the last trimester – a feature of maternal iron excess?

2001 • 137 citations

Ferritin protects endothelial cells from oxidized low density lipoprotein in vitro.

1995 • 137 citations

High <scp>D</scp>-Glucose–Induced Changes in Endothelial Ca2+/EDRF Signaling are Due to Generation of Superoxide Anions

1996 • 136 citations

New aspects of the insulin resistance syndrome: impact on haematological parameters

2001 • 132 citations

Regulation of iron metabolism in HepG2 cells: A possible role for cytokines in the hepatic deposition of iron

1993 • 123 citations

Prevalence of hereditary haemochromatosis in late-onset type 1 diabetes mellitus: a retrospective study

2001 • 122 citations

The effect of diet on plasma homocysteine concentrations in healthy male subjects

1999 • 118 citations

Low iron status and enhanced insulin sensitivity in lacto-ovo vegetarians

2001 • 114 citations

Deferoxamine Therapy in High-Ferritin Diabetes

1989 • 112 citations

Factors determining glucose tolerance in patients with thalassemia major.

1993 • 111 citations

Insulin Resistance and Iron Overload

1983 • 110 citations

The haemochromatotic human pancreas: a quantitative immunohistochemical and ultrastructural study

1987 • 109 citations

Role of Hemochromatosis C282Y and H63D Mutations in HFE Gene in Development of Type 2 Diabetes and Diabetic Nephropathy

2001 • 109 citations

Effect of dietary protein on in vivo insulin action and liver glycogen repletion

1989 • 97 citations

Oxidative stress impairs insulin internalization in endothelial cells in vitro

2001 • 96 citations

Localization of transferrin receptors and insulin-like growth factor II receptors in vesicles from 3T3-L1 adipocytes that contain intracellular glucose transporters.

1989 • 96 citations

PREVALENCE OF GENETIC HAEMOCHROMATOSIS AMONG DIABETIC PATIENTS

1989 • 92 citations

Insulin resistance and hyperinsulinemia in homozygous β-thalassemia

1995 • 83 citations

Ascorbic Acid Metabolism and Polyol Pathway in Diabetes

1989 • 83 citations

Diabetes-Induced Endothelial Dysfunction is Prevented by Long-Term Treatment with the Modified Iron Chelator, Hydroxyethyl Starch Conjugated-Deferoxamine

1997 • 81 citations

Low density lipoprotein oxidation by stimulated neutrophils and ferritin

1992 • 80 citations

VENESECTION THERAPY IN IDIOPATHIC HAEMOCHROMATOSIS: An Analysis of 40 treated and 18 untreated patients

1969 • 78 citations

Maternal Serum Ferritin and Gestational Impaired Glucose Tolerance

1997 • 77 citations

Impairment of Endothelium-Dependent Relaxation by Increasing Percentages of Glycosylated Human Hemoglobin

1996 • 77 citations

Transcriptional Regulation of Ferritin Messenger Ribonucleic Acid Levels by Insulin in Cultured Rat Glioma Cells

1991 • 76 citations

Iron overload diminishes atherosclerosis in apoE-deficient mice

2001 • 76 citations

Prevalence of Genetic Hemochromatosis in a Cohort of Italian Patients with Diabetes Mellitus

1998 • 75 citations

Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo.

1994 • 67 citations

Diabetic Nephropathy in Hypertransfused Patients With β-Thalassemia: The role of oxidative stress

1998 • 63 citations

Patients with type 2 diabetes have a high frequency of the C282Y mutation of the hemochromatosis gene.

1998 • 54 citations

Lysosomal Iron Accumulation in Diabetic Nephropathy

1994 • 53 citations

THE TREATMENT OF HEMOCHROMATOSIS BY MASSIVE VENESECTION

1953 • 53 citations

Usefulness of Biochemical Screening of Diabetic Patients for Hemochromatosis

1990 • 52 citations

Nonenzymatic Glycation of Transferrin: Decrease of Iron-Binding Capacity and Increase of Oxygen Radical Production.

1995 • 51 citations

Effects of an extracellular metal chelator on neurovascular function in diabetic rats

2001 • 50 citations

High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions

1996 • 45 citations

Large amount of (Apo)ferritin in the pancreatic insulin cell and its stimulation by glucose

1994 • 45 citations

Hematocrit and Risk of NIDDM

1996 • 43 citations

Coronary Microvascular Adaptation to Myocardial Metabolic Demand Can Be Restored by Inhibition of Iron-Catalyzed Formation of Oxygen Free Radicals in Type 2 Diabetic Patients

2002 • 43 citations

Ascorbic acid metabolism and polyol pathway in diabetes

1989 • 43 citations

Response to repeated phlebotomies in patients with non-insulin-dependent diabetes mellitus

1994 • 42 citations

Iron, lactoferrin and iron regulatory protein activity in the synovium; relative importance of iron loading and the inflammatory response

1998 • 41 citations

Liver Iron Stores in Patients With Non-Insulin-Dependent Diabetes Mellitus

1994 • 40 citations

Radial artery wall alterations in genetic hemochromatosis before and after iron depletion therapy

2000 • 39 citations

Deferoxamine therapy in high-ferritin diabetes

1989 • 39 citations

Major factors in the development of diabetes mellitus in 10,000 men

1975 • 37 citations

No Effect of Deferoxamine Therapy on Glucose Homeostasis and Insulin Secretion in Individuals With NIDDM and Elevated Serum Ferritin

1993 • 32 citations

Therapeutic efficiency of phlebotomy in posttransplant hypertension associated with erythrocytosis.

1993 • 30 citations

Adipocyte insulin binding and insulin sensitivity in ?brittle? diabetes

1984 • 30 citations

Hemochromatosis associated with endothelial dysfunction: evidence for the role of iron stores in early atherogenesis

1999 • 24 citations

Treatment of resistant hypertension by phlebotomy

1985 • 22 citations

No effect of deferoxamine therapy on glucose homeostasis and insulin secretion in individuals with NIDDM and elevated serum ferritin

1993 • 17 citations

Regulators of iron balance in humans [see comments]

1994 • 12 citations

Hematocrit and risk of NIDDM

1996 • 9 citations

Diabetes Prevention in BB Rats by Frequent Blood Withdrawal Started at a Young Age

1988 • 9 citations

Diabetes prevention in BB rats by frequent blood withdrawal started at a young age

1988 • 6 citations

Deleted Work

1955 • 0 citations