Regulation of iron metabolism in HepG2 cells: A possible role for cytokines in the hepatic deposition of iron

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Isolation and characterization of genomic and cDNA clones of human erythropoietin

1985 • 1,101 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm

1988 • 565 citations

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

1985 • 464 citations

Regulation of Synthesis and Turnover of Ferritin in Rat Liver

1966 • 329 citations

Annotation: THE ANAEMIA OF CHRONIC DISORDERS

1971 • 305 citations

The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene.

1988 • 295 citations

Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macrophages.

1980 • 260 citations

Ferritin Synthesis in Inflammation: I. PATHOGENESIS OF IMPAIRED IRON RELEASE

1977 • 254 citations

Action of recombinant human interleukin 6, interleukin 1β and tumor necrosis factor α on the mRNA induction of acute‐phase proteins

1988 • 254 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

1989 • 244 citations

Noncoding 3′ sequences of the transferrin receptor gene are required for mRNA regulation by iron.

1987 • 220 citations

Interleukin-6 is the Major Regulator of Acute Phase Protein Synthesis in Rat and Man

1989 • 182 citations

STUDIES ON THE PATHOGENESIS OF FEVER

1955 • 145 citations

Interleukin 1 induces ferritin heavy chain in human muscle cells

1990 • 135 citations

Interactions between isolated hepatocytes and kupffer cells in iron metabolism: A possible role for ferritin as an iron carrier protein

1988 • 134 citations

Interleukin‐6

1989 • 127 citations

Iron metabolism in the erythrophagocytosing Kupffer cell

1988 • 124 citations

Uptake of iron from transferrin by isolated rat hepatocytes. A redox-mediated plasma membrane process?

1988 • 121 citations

Effect of inflammatory agents and interleukin 1 on iron and zinc metabolism

1984 • 116 citations

Structural requirements of iron-responsive elements for binding of the protein involved in both transferrin receptor and ferritin mRNA post-transcriptional regulation

1990 • 114 citations

Detection and isolation of a hepatic membrane receptor for ferritin.

1983 • 109 citations

Iron Up-modulates the Expression of Transferrin Receptors during Monocyte-Macrophage Maturation

1989 • 105 citations

The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor.

1988 • 87 citations

Differential turnover of rat liver isoferritins.

1980 • 76 citations

Purification and characterization of recombinant human interleukin-1β produced in Escherichia coli

1987 • 76 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA

1989 • 72 citations

Iron uptake and regulation of ferritin synthesis by hepatoma cells in hormone-supplemented serum-free media.

1983 • 51 citations

The effect of interleukin‐1 on iron metabolism in rats

1991 • 19 citations

Recombinant human tumor necrosis factor depresses serum iron in mice.

1987 • 15 citations