Helicobacter pylori cagA Status and s and m Alleles of vacA in Isolates from Individuals with a Variety of H. pylori -Associated Gastric Diseases

cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

1996 • 1,883 citations

Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.

1995 • 1,613 citations

Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori

1995 • 1,551 citations

Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.

1993 • 1,262 citations

Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori

1997 • 649 citations

Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin

1995 • 594 citations

Characterization of a Helicobacter pylori neutrophil-activating protein

1995 • 317 citations

Variants of the 3′ Region of the cagA Gene in Helicobacter pylori Isolates from Patients with Different H. pylori -Associated Diseases

1998 • 289 citations

Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan

1997 • 263 citations

The Interrelationship between Cytotoxin-Associated Gene A, Vacuolating Cytotoxin, and Helicobacter pylori-Related Diseases

1996 • 256 citations

Diversity of Helicobacter pylori vacA and cagA Genes and Relationship to VacA and CagA Protein Expression, Cytotoxin Production, and Associated Diseases

1998 • 210 citations

Allelic variation in the cagA gene of Helicobacter pylori obtained from Korea compared to the United States.

1996 • 179 citations

Equally high prevalences of infection with cagA-positive Helicobacter pylori in Chinese patients with peptic ulcer disease and those with chronic gastritis-associated dyspepsia

1997 • 178 citations

Ordered cosmid library and high‐resolution physical—genetic map of Helicobacter pylori strain NCTC11638

1994 • 107 citations

Country-specific constancy by age incagA+ proportion ofHelicobacter pylori infections

1997 • 107 citations

cagA -Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct

1998 • 104 citations

Helicobacter pyloriPhenotypes Associated with Peptic Ulceration

1994 • 76 citations

Restriction fragment length polymorphism in the adhesin gene hpaA of Helicobacter pylori.

1995 • 37 citations

Diversity in the Variable Region ofHelicobacter pylori cagAGene Involves More Than Simple Repetition of a 102-Nucleotide Sequence

1998 • 19 citations