Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor

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Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor

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A Tyrosine Kinase Created by Fusion of thePDGFRAandFIP1L1Genes as a Therapeutic Target of Imatinib in Idiopathic Hypereosinophilic Syndrome

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Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

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Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors.

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KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

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Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy

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A Network Algorithm for Performing Fisher's Exact Test inr×cContingency Tables

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STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

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High frequency of point mutations clustered within the adenosine triphosphate–binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance

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KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors

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Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas

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KIT Mutations Are Common in Incidental Gastrointestinal Stromal Tumors One Centimeter or Less in Size

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The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations

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Effect of c-kit Mutation on Prognosis of Gastrointestinal Stromal Tumors

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Molecular Targeting of Platelet-Derived Growth Factor B by Imatinib Mesylate in a Patient With Metastatic Dermatofibrosarcoma Protuberans

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Mutations in Exons 9 and 13 of KIT Gene Are Rare Events in Gastrointestinal Stromal Tumors

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ARG tyrosine kinase activity is inhibited by STI571

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New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis

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Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors

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The Predictive Value of HER2 in Breast Cancer

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