New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Angiogenesis.

1992 • 2,581 citations

Receptor Protein-Tyrosine Kinases and Their Signal Transduction Pathways

1994 • 1,309 citations

Anti-Angiogenesis

1972 • 1,167 citations

Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors

1997 • 1,098 citations

Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice

1999 • 990 citations

Kinetics of Response in Lymphoid Tissues to Antiretroviral Therapy of HIV-1 Infection

1997 • 631 citations

Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of nNOS-Syntrophin Complex

1999 • 530 citations

The role of vascular endothelial growth factor in pathological angiogenesis

1995 • 419 citations

Structure of the FGF Receptor Tyrosine Kinase Domain Reveals a Novel Autoinhibitory Mechanism

1996 • 376 citations

Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo

1993 • 367 citations

Molecular angiogenesis

1999 • 228 citations

The role of vascular endothelial growth factor in blood vessel formation

1996 • 163 citations

Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis

1995 • 145 citations

Antiangiogenic tumour therapy: will it work?

1998 • 123 citations

Angiogenesis as a Target for Tumor Treatment

1997 • 104 citations

The Reaction of α-Diazo-β-hydroxy Esters with Boron Trifluoride Etherate: Generation and Rearrangement of Destabilized Vinyl Cations. A Detailed Experimental and Theoretical Study

1996 • 104 citations

Dianilinophthalimides: Potent and Selective, ATP-Competitive Inhibitors of the EGF-Receptor Protein Tyrosine Kinase

1994 • 88 citations

Receptor tyrosine kinases as targets for inhibition of angiogenesis

1997 • 78 citations

The influence of angiogenesis research on management of patients with breast cancer

1995 • 73 citations

Characterization and Kinetic Mechanism of Catalytic Domain of Human Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase (VEGFR2 TK), a Key Enzyme in Angiogenesis

1998 • 71 citations

Aminoacetyl Moiety as a Potential Surrogate for Diacylhydrazine Group of SC-51089, a Potent PGE₂ Antagonist, and Its Analogs

1996 • 62 citations

Mechanisms of angiogenesis in vascular disorders: Potential therapeutic targets

1998 • 48 citations

Pyrophtalones VII. Synthèse et activité anti-inflammatoire de (pyridinyl-4)-2 indanediones-1,3 substituées sur le noyau benzénique et/ou sur l'hétérocycle

1987 • 29 citations

Aza analogues of protoberberine and phthalideisoquinoline alkaloids

1986 • 12 citations

Untitled

1999 • 6 citations

Case 46-1989

1989 • 3 citations