A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment

A decade of molecular biology of retinoic acid receptors

1996 • 2,893 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

Embryonic retinoic acid synthesis is essential for early mouse post-implantation development

1999 • 1,051 citations

Nonsteroid nuclear receptors: What Are genetic studies telling us about their role in real life?

1995 • 1,011 citations

Function of the retinoic acid receptors (RARs) during development: (I) Craniofacial and skeletal abnormalities in RAR double mutants

1994 • 755 citations

An analysis of the syndrome of malformations induced by maternal vitamin a deficiency. Effects of restoration of vitamin a at various times during gestation

1953 • 754 citations

Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis.

1991 • 730 citations

Genetic analysis of RXRα developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis

1994 • 684 citations

Function of retinoic acid receptor γ in the mouse

1993 • 595 citations

Families of retinoid dehydrogenases regulating vitamin A function

2000 • 573 citations

Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development

1997 • 527 citations

Fgf8is required for pharyngeal arch and cardiovascular development in the mouse

2002 • 446 citations

Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development

1997 • 428 citations

Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse

2001 • 400 citations

Retinoic acid synthesis and hindbrain patterning in the mouse embryo

2000 • 377 citations

In vivo functional analysis of the Hoxa-1 3′ retinoic acid response element (3′ RARE)

1997 • 333 citations

Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH

2001 • 281 citations

Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue ofRaldh2null mutant mice

2002 • 251 citations

Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse

2002 • 244 citations

Role of the retinoic acid receptor beta (RARbeta) during mouse development.

1997 • 228 citations

Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina

2003 • 223 citations

Temporally-regulated retinoic acid depletion produces specific neural crest, ocular and nervous system defects

1997 • 217 citations

Embryonic retinoic acid synthesis is required for forelimb growth and anteroposterior patterning in the mouse

2002 • 211 citations

Retinoic Acid: Its Biosynthesis and Metabolism

1999 • 182 citations

Vitamin A Deficiency Results in the Dose-Dependent Acquisition of Anterior Character and Shortening of the Caudal Hindbrain of the Rat Embryo

2000 • 180 citations

A retinoic acid synthesizing enzyme in ventral retina and telencephalon of the embryonic mouse

2000 • 165 citations

RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development

2000 • 162 citations

Mesenchymal/Epithelial Induction Mediates Olfactory Pathway Formation

2000 • 157 citations

Dorsal and ventral retinal territories defined by retinoic acid synthesis, break-down and nuclear receptor expression

1999 • 149 citations

The RXRα ligand-dependent activation function 2 (AF-2) is important for mouse development

1998 • 136 citations

Vax2inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma

2002 • 131 citations

Active repression by unliganded retinoid receptors in development

2003 • 130 citations

Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning

2001 • 128 citations

Aldehyde Dehydrogenase 6, a Cytosolic Retinaldehyde Dehydrogenase Prominently Expressed in Sensory Neuroepithelia during Development

2000 • 128 citations

Mouse Retinal Dehydrogenase 4 (RALDH4), Molecular Cloning, Cellular Expression, and Activity in 9-cis-Retinoic Acid Biosynthesis in Intact Cells

2003 • 120 citations

Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo

2002 • 119 citations

Identification of RALDH-3, a novel retinaldehyde dehydrogenase, expressed in the ventral region of the retina

2000 • 107 citations

Retinoic acid-induced developmental defects are mediated by RARβ/RXR heterodimers in the pharyngeal endoderm

2003 • 105 citations

Craniosynostosis Syndromes: From Genes to Premature Fusion of Skull Bones

1999 • 98 citations

Recent Advances in Primary Palate and Midface Morphogenesis Research

1992 • 85 citations

Effects of excess vitamin A on development of cranial neural crest-derived structures: A neonatal and embryologic study

2000 • 84 citations

Developing with lethal RA levels: genetic ablation ofRargcan restore the viability of mice lackingCyp26a1

2003 • 81 citations

Marrying Planning, Economics and Environment: Is South Africa ahead of the curve?

2000 • 70 citations

Retinoid Signaling Is Required to Complete the Vertebrate Cardiac Left/Right Asymmetry Pathway

2000 • 69 citations

Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXRα

2001 • 51 citations

Functions of RARs and RXRs in vivo: Genetic dissection of the retinoid signaling pathway

2003 • 48 citations

Development of Dorsal–Ventral Polarity in the Optic Vesicle and Its Presumptive Role in Eye Morphogenesis As Shown by Embryonic Transplantation and in Ovo Explant Culturing

2002 • 38 citations

Choanal Atresia

1995 • 3 citations

Choanal atresia.

1995 • 1 citations