An increase in endothelial intracellular calcium and F-actin precedes the extravasation of interleukin-2-activated lymphocytes.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Molecular architecture of basement membranes

1990 • 937 citations

Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation.

1995 • 451 citations

Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells.

1993 • 340 citations

Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces F-actin, and promotes albumin diffusion across cultured endothelial monolayers.

1986 • 289 citations

Protein kinase C phosphorylates caldesmon₇₇ and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers

1992 • 163 citations

TNF-alpha induces endothelial cell F-actin depolymerization, new actin synthesis, and barrier dysfunction

1993 • 157 citations

Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).

1994 • 132 citations

Lymphocyte adhesion can be regulated by cytoskeleton-associated, PMA-induced capping of surface receptors

1992 • 108 citations

Lymphocyte adhesion-dependent calcium signaling in human endothelial cells.

1995 • 103 citations

Phosphatidic Acid and Lysophosphatidic Acid Induce Haptotactic Migration of Human Monocytes

1995 • 100 citations

IL-2-activated human killer lymphocytes but not their secreted products mediate increase in albumin flux across cultured endothelial monolayers. Implications for vascular leak syndrome.

1989 • 90 citations

Mechanisms of α-thrombin, histamine, and bradykinin induced endothelial permeability

1996 • 88 citations

TNFa‐Induced Expression of Endothelial Adhesion Molecules, ICAM‐1 and VCAM‐1, is Linked to Protein Kinase C Activation

1992 • 83 citations

Tumor necrosis factor-alpha augments pulmonary arterial transendothelial albumin flux in vitro

1990 • 81 citations

Time course of thrombin-induced increase in endothelial permeability: relationship to Ca2+i and inositol polyphosphates

1992 • 66 citations

Continuous infusion of recombinant interleukin-2 with or without autologous lymphokine activated killer cells for the treatment of advanced renal cell carcinoma

1992 • 64 citations

Mechanisms of interleukin-2-induced hepatic toxicity.

1996 • 64 citations

Interleukin 2 induced leukocyte adhesion to the normal and tumor microvascular endothelium in vivo and its inhibition by dextran sulfate: implications for vascular leak syndrome.

1991 • 62 citations

Chemotactic desensitization of neutrophils demonstrates interleukin-8 (IL-8)-dependent and IL-8-independent mechanisms of transmigration through cytokine-activated endothelium.

1993 • 62 citations

Mechanism of cultured endothelial injury induced by lymphokine-activated killer cells.

1988 • 57 citations

Tumor Necrosis Factor Alters Cytoskeletal Organization and Barrier Function of Endothelial Cells

1991 • 53 citations

The preparation and use of fluorescent-protein conjugates for microvascular research

1984 • 52 citations

Influence of extracellular matrix in tumor necrosis factor-induced increase in endothelial permeability

1992 • 50 citations

Initial contact and subsequent adhesion of human neutrophils or monocytes to human aortic endothelial cells releases an endothelial intracellular calcium store.

1994 • 46 citations

Pentoxifylline inhibits interleukin-2-induced toxicity in C57BL/6 mice but preserves antitumor efficacy.

1992 • 42 citations

Pentoxifylline inhibits interleukin-2-induced leukocyte-endothelial adherence and reduces systemic toxicity.

1991 • 39 citations

Effect of fibronectin on permeability of normal and TNF-treated lung endothelial cell monolayers

1993 • 37 citations

Investigation of Interleukin 2 Receptors on Human Endothelial Cells

1991 • 27 citations

Human recombinant interleukin 2-activated sheep lymphocytes lyse sheep pulmonary microvascular endothelial cells

1989 • 14 citations

Interleukin 2 Induces Tumor Necrosis Factor Gene ExpressionIn Vivo

1991 • 11 citations