Fine Mapping of 28S rRNA Sites Specifically Cleaved in Cells Undergoing Apoptosis

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

1993 • 1,888 citations

Developmental cell death: morphological diversity and multiple mechanisms

1990 • 1,695 citations

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1993 • 1,144 citations

Apoptosis

1993 • 972 citations

RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes.

1987 • 943 citations

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)

1991 • 884 citations

An evolutionary perspective on apoptosis

1994 • 758 citations

Programmed cell death, apoptosis and killer genes

1993 • 396 citations

A Compilation of large subunit RNA sequences presented in a structural format

1988 • 377 citations

Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro.

1991 • 358 citations

Interferon Action: RNA Cleavage Pattern of a (2′-5′)Oligoadenylate—Dependent Endonuclease

1981 • 357 citations

The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells

1991 • 330 citations

The Interferon-induced Double-Stranded RNA-Activated Protein Kinase Induces Apoptosis

1994 • 322 citations

Variation among human 28S ribosomal RNA genes.

1985 • 294 citations

Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus

1993 • 284 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Dinoflagellates in evolution. A molecular phylogenetic analysis of large subunit ribosomal RNA

1989 • 259 citations

The RNA N-glycosidase activity of ricin A-chain.

1988 • 256 citations

Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)_nA) in interferon-treated cells

1981 • 245 citations

Evolutionary conservation of structure and function of high molecular weight ribosomal RNA

1988 • 170 citations

CTL: virus control cells first and cytolytic cells second? DNA fragmentation, apoptosis and the prelytic halt hypothesis

1989 • 169 citations

The structure of rat 28S ribosomal ribonucleic add inferred from the sequence of nuclotides in a gene

1983 • 168 citations

DNA in chromatin of irradiated lymphoid tissues degrades in vivo into regular fragments

1976 • 145 citations

Programmed cell death (apoptosis) is induced rapidly and with positive cooperativity by activation of cyclic adenosine monophosphate‐kinase I in a myeloid leukemia cell line

1991 • 120 citations

Control of the ppp(A2′p)_nA System in HeLa Cells

1982 • 115 citations

Molecular coevolution among cryptically simple expansion segments of eukaryotic 26S/28S rRNAs.

1988 • 113 citations

Comparisons of large subunit rRNAs reveal some eukaryote-specific elements of secondary structure

1987 • 103 citations

The involvement of oncogenes and tumor suppressor genes in the control of apoptosis

1992 • 99 citations

Separate metabolic pathways leading to DNA fragmentation and apoptotic chromatin condensation.

1994 • 98 citations

Apoptosis, lymphocytotoxicity and the containment of viral infections

1985 • 92 citations

12 Divalent Metal Ions in RNA Folding and Catalysis

1993 • 84 citations

Multiple apoptotic death types triggered through activation of separate pathways by cAMP and inhibitors of protein phosphatases in one (IPC leukemia) cell line

1994 • 84 citations

Molecular genetics of cell death in the nematode Caenorhabditis elegans

1992 • 77 citations

The Expression of cAMP-Dependent Protein Kinase Subunits in Primary Rat Hepatocyte Cultures. Cyclic AMP Down-Regulates Its Own Effector System by Decreasing the Amount of Catalytic Subunit and Increasing the mRNAs for the Inhibitory (R) Subunits of cAMP-Dependent Protein Kinase

1990 • 71 citations

Secondary structure constraints on the evolution of Drosophila 28 S ribosomal RNA expansion segments

1991 • 62 citations

Internucleosomal Deoxyribonucleic Acid Cleavage Activity in Apoptotic Thymocytes: Detection and Endocrine Regulation*

1991 • 61 citations

Selective cleavage of 28S rRNA variable regions V3 and V13 in myeloid leukemia cell apoptosis

1993 • 57 citations

Ribosomal RNA Probes for Detection and Identification of Species

2003 • 47 citations

Cleaved intracellular plasminogen activator inhibitor 2 in human myeloleukaemia cells is a marker of apoptosis

1994 • 46 citations

Apoptosis II: The molecular basis of apoptosis in disease

1994 • 43 citations

The sequence of 28S ribosomal RNA varies within and between human cell lines

1993 • 42 citations

Mechanism of interferon action. Kinetics of interferon action in mouse L929 cells: Phosphorylation of protein synthesis initiation factor eIF-2 and ribosome-associated protein P1

1979 • 41 citations

Probing the structure of mouse Ehrlich ascites cell 5.8S, 18S and 28S ribosomal RNAin situ

1994 • 35 citations

Comparison of primary and secondary 26S rRNA structures in twoTetrahymena species: Evidence for a strong evolutionary and structural constraint in expansion segments

1990 • 32 citations

Mapping RNA Regions in Eukaryotic Ribosomes That Are Accessible to Methidiumpropyl-EDTA.cntdot.Fe(II) and EDTA.cntdot.Fe(II)

1994 • 30 citations

γ-Ray-induced Transcription and Apoptosis-associated Loss of 28S rRNA in Interphase Human Lymphocytes

1993 • 28 citations

Apoptotic cell death analyzed at the molecular level by two‐dimensional gel electrophoresis

1994 • 23 citations

Superinfection-induced apoptosis and its correlation with the reduction of viral progeny in cells persistently infected with Hz-1 baculovirus

1993 • 23 citations

On growth regulation of the rat promyelocytic leukemia (BNML): Growth inhibition and eradication of clonogenic cells by cholera toxin

1986 • 16 citations