Minireview: Epigenetics of Obesity and Diabetes in Humans

A core gut microbiome in obese and lean twins

2008 • 7,389 citations

Obesity alters gut microbial ecology

2005 • 5,818 citations

The gut microbiota as an environmental factor that regulates fat storage

2004 • 5,730 citations

The Human Microbiome Project

2007 • 5,410 citations

Human DNA methylomes at base resolution show widespread epigenomic differences

2009 • 4,388 citations

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

2009 • 4,036 citations

Epigenetic differences arise during the lifetime of monozygotic twins

2005 • 3,451 citations

Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine

2006 • 3,102 citations

Persistent epigenetic differences associated with prenatal exposure to famine in humans

2008 • 2,912 citations

INFANT MORTALITY, CHILDHOOD NUTRITION, AND ISCHAEMIC HEART DISEASE IN ENGLAND AND WALES

1986 • 2,727 citations

Complementing the Genome with an “Exposome”: The Outstanding Challenge of Environmental Exposure Measurement in Molecular Epidemiology

2005 • 1,971 citations

The NIH Roadmap Epigenomics Mapping Consortium

2010 • 1,811 citations

Epigenome-wide association studies for common human diseases

2011 • 1,201 citations

Metagenomics: Genomic Analysis of Microbial Communities

2004 • 1,078 citations

Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics

2004 • 1,052 citations

The Prevention of Accidents

1934 • 973 citations

The core gut microbiome, energy balance and obesity

2009 • 941 citations

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child’s Later Adiposity

2011 • 731 citations

DNA methylation profiles in monozygotic and dizygotic twins

2009 • 666 citations

Concentrations of Urinary Phthalate Metabolites Are Associated with Increased Waist Circumference and Insulin Resistance in Adult U.S. Males

2007 • 607 citations

Obesity, Diabetes, and Gut Microbiota

2010 • 597 citations

Metagenomics: DNA sequencing of environmental samples

2005 • 585 citations

Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density

2009 • 565 citations

Human body burdens of chemicals used in plastic manufacture

2009 • 562 citations

Environmental epigenetics

2010 • 510 citations

Implications of the exposome for exposure science

2010 • 395 citations

Toxicology and genetic toxicology in the new era of “toxicogenomics”: impact of “-omics” technologies

2002 • 385 citations

Genetic Control of Individual Differences in Gene-Specific Methylation in Human Brain

2010 • 376 citations

Quantitative Phylogenetic Assessment of Microbial Communities in Diverse Environments

2007 • 353 citations

Review: Chromatin Structural Features and Targets That Regulate Transcription

2000 • 348 citations

Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index

2010 • 327 citations

Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity

2011 • 250 citations

Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus

2007 • 239 citations

Epigenetics: molecular mechanisms and implications for disease

2009 • 213 citations

Impact of environmental endocrine disrupting chemicals on the development of obesity

2010 • 194 citations

Obesity and the built environment: changes in environmental cues cause energy imbalances

2008 • 174 citations

Minireview: Epigenetic Programming of Diabetes and Obesity: Animal Models

2012 • 172 citations

Systems biology of innate immunity

2008 • 154 citations

Exposure to hexachlorobenzene during pregnancy increases the risk of overweight in children aged 6 years

2008 • 153 citations

Productivity Improvements in Rice

2003 • 146 citations

Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans

2011 • 140 citations

Cytosine Methylation Dysregulation in Neonates Following Intrauterine Growth Restriction

2010 • 130 citations

Epigenetics and MicroRNAs

2007 • 125 citations

How Much Disease Burden can be Prevented by Environmental Interventions?

2006 • 123 citations

Maternal levels of dichlorodiphenyl-dichloroethylene (DDE) may increase weight and body mass index in adult female offspring

2008 • 118 citations

LINE-1 DNA methylation is inversely correlated with cord plasma homocysteine in man: A preliminary study

2009 • 110 citations

Application of OMICS technologies in occupational and environmental health research; current status and projections

2009 • 109 citations

Exercise Like a Hunter-Gatherer: A Prescription for Organic Physical Fitness

2011 • 101 citations

DNA Methylation: An Introduction to the Biology and the Disease-Associated Changes of a Promising Biomarker

2008 • 98 citations

A systems biology approach to understanding atherosclerosis

2010 • 80 citations

The impact of new research technologies on our understanding of environmental causes of disease: the concept of clinical vulnerability

2009 • 72 citations

From Waddington’s epigenetic landscape to small noncoding RNA: some important milestones in the history of epigenetics research

2011 • 72 citations

Correlation of Global and Gene-Specific DNA Methylation in Maternal-Infant Pairs

2010 • 71 citations

Use of ‘Omic’ technologies to study humans exposed to benzene

2005 • 47 citations

Epigenetic Basis for Fetal Origins of Age-Related Disease

2010 • 47 citations

Childhood obesity—methylate now, pay later?

2011 • 9 citations