The diabetic milieu modulates the advanced glycation end product-receptor complex in the mesangium by inducing or upregulating galectin-3 expression.

Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.

1992 • 1,488 citations

Galectins. Structure and function of a large family of animal lectins.

1994 • 1,487 citations

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

1997 • 1,210 citations

Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

1991 • 1,161 citations

Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging.

1994 • 863 citations

Expression of galectin-3 modulates T-cell growth and apoptosis.

1996 • 771 citations

Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.

1997 • 701 citations

Immunochemical detection of advanced glycosylation end products in vivo.

1992 • 496 citations

Identification of Galectin-3 As a High-Affinity Binding Protein for Advanced Glycation End Products (AGE): A New Member of the AGE-Receptor Complex

1995 • 410 citations

Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor.

1992 • 353 citations

Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins.

1996 • 340 citations

Galectin-3 promotes adhesion of human neutrophils to laminin.

1996 • 334 citations

Endogenous galactoside-binding lectins: a new class of functional tumor cell surface molecules related to metastasis

1987 • 307 citations

Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease.

1994 • 298 citations

Advanced Glycation End Products-driven Angiogenesis in Vitro

1997 • 272 citations

Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin.

1992 • 264 citations

Regulation of secretion and surface expression of Mac-2, a galactoside-binding protein of macrophages.

1994 • 246 citations

Human and rat mesangial cell receptors for glucose-modified proteins: potential role in kidney tissue remodelling and diabetic nephropathy.

1991 • 243 citations

Endogenous lectins from cultured cells: nuclear localization of carbohydrate-binding protein 35 in proliferating 3T3 fibroblasts.

1987 • 242 citations

Regulation of Cellular Adhesion to Extracellular Matrix Proteins by Galectin-3

1998 • 223 citations

Advanced glycation end products and their receptors co-localise in rat organs susceptible to diabetic microvascular injury

1997 • 214 citations

Functional evidence that cell surface galectin-3 mediates homotypic cell adhesion.

1995 • 197 citations

Galectin-3 Stimulates Cell Proliferation

1998 • 188 citations

.epsilon.BP, a .beta.-galactoside-binding animal lectin, recognizes IgE receptor (Fc.epsilon.RI) and activates mast cells

1993 • 169 citations

Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-α and inducible nitric oxide synthase in diabetic rat glomeruli

1999 • 150 citations

Upregulation of Mesangial Growth Factor and Extracellular Matrix Synthesis by Advanced Glycation End Products Via a Receptor-Mediated Mechanism

1997 • 129 citations

Mechanisms of Glucose-Enhanced Extracellular Matrix Accumulation in Rat Glomerular Mesangial Cells

1994 • 127 citations

Role of the Carboxyl-Terminal Lectin Domain in Self-Association of Galectin-3

1998 • 124 citations

The HumanLGALS3(Galectin-3) Gene: Determination of the Gene Structure and Functional Characterization of the Promoter,

1998 • 117 citations

S-type mammalian lectins in allergic inflammation

1993 • 115 citations

Functional analysis of pRb2/p130 interaction with cyclins.

1996 • 109 citations

Characterization of the Advanced Glycation End-Product Receptor Complex in Human Vascular Endothelial Cells

1999 • 107 citations

Protein glycation in the kidney: Role in diabetes and aging

1996 • 105 citations

Epithelial galectin-3 during human nephrogenesis and childhood cystic diseases.

1997 • 95 citations

Modulation of Functional Properties of Galectin-3 by Monoclonal Antibodies Binding to the Non-Lectin Domains

1996 • 91 citations

Galectin-3 modulates rat mesangial cell proliferation and matrix synthesis during experimental glomerulonephritis induced by anti-Thy1.1 antibodies

1999 • 84 citations

Effect of diabetes and aminoguanidine therapy on renal advanced glycation end-product binding

1999 • 77 citations

Expression of carbohydrate binding protein 35 in human fibroblasts: Variations in the levels of mRNA, protein, and isoelectric species as a function of replicative competence*1

1991 • 47 citations

Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli.

1990 • 43 citations

Early, but Not Advanced, Glomerulopathy Is Reversed by Pancreatic Islet Transplants in Experimental Diabetic Rats: Correlation With Glomerular Extracellular Matrix mRNA Levels

1997 • 34 citations

Low expression of AGE-receptor-1 in NOD mouse mesangial cells: Possible link to diabetic nephropathy.

1996 • 8 citations

Formation and ways of detecting advanced glycation end-products in isolated human glomerular basement membrane and human serum albumin nonenzymatically glycated in vitro

1989 • 4 citations