Cleavage of β-Catenin by Calpain in Prostate and Mammary Tumor Cells

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

1997 • 3,847 citations

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

1997 • 3,234 citations

Wnt signaling and cancer

2000 • 3,215 citations

Delineation of prognostic biomarkers in prostate cancer

2001 • 1,694 citations

Caught up in a Wnt storm: Wnt signaling in cancer

2003 • 1,473 citations

Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

1997 • 1,215 citations

β-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression

2000 • 760 citations

Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3.

1998 • 441 citations

Beta-catenin mutations in human prostate cancer.

1998 • 368 citations

Neoplastic Transformation of RK3E by Mutant β-Catenin Requires Deregulation of Tcf/Lef Transcription but Not Activation of c-myc Expression

1999 • 313 citations

Rapid ("warm") autopsy study for procurement of metastatic prostate cancer.

2000 • 227 citations

Expression of metalloproteinase genes in human prostate cancer

1991 • 222 citations

NH2-terminal Deletion of β-Catenin Results in Stable Colocalization of Mutant β-Catenin with Adenomatous Polyposis Coli Protein and Altered MDCK Cell Adhesion

1997 • 220 citations

Overexpression of cyclin D1 is associated with metastatic prostate cancer to bone.

2000 • 218 citations

Δn89β-Catenin Induces Precocious Development, Differentiation, and Neoplasia in Mammary Gland

2001 • 200 citations

Deletion of an Amino-Terminal Sequence Stabilizes β-Catenin In Vivo and Promotes Hyperphosphorylation of the Adenomatous Polyposis Coli Tumor Suppressor Protein

1996 • 186 citations

Activation of β-catenin in epithelial and mesenchymal hepatoblastomas

2000 • 169 citations

The Role of Calpain in the Proteolytic Cleavage of E-cadherin in Prostate and Mammary Epithelial Cells

2003 • 169 citations

β-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland

2001 • 166 citations

In vitro evidence for complex modes of nuclear β-catenin signaling during prostate growth and tumorigenesis

2002 • 160 citations

No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas.

1996 • 109 citations

Cyclin D1 expression in human prostate carcinoma cell lines and primary tumors

1998 • 84 citations

Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/β-catenin-regulated cell proliferation

2002 • 81 citations

APC truncation and increased β-catenin levels in a human breast cancer cell line

2000 • 79 citations

T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant β-catenin

1999 • 65 citations

Constitutive activation of pp125fak in newly isolated human breast cancer cell lines

1999 • 51 citations

APC Gene Mutations in Human Prostate Cancer

1996 • 44 citations