Latently Expressed Human Herpesvirus 8-Encoded Interferon Regulatory Factor 2 Inhibits Double-Stranded RNA-Activated Protein Kinase

Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma

1994 • 5,605 citations

Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas

1995 • 2,833 citations

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease [see comments]

1995 • 2,169 citations

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

1996 • 1,464 citations

Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV

1996 • 926 citations

PKR; a sentinel kinase for cellular stress

1999 • 823 citations

p53 inhibition by the LANA protein of KSHV protects against cell death

1999 • 699 citations

The Double-Stranded RNA-Dependent Protein Kinase PKR: Structure and Function

1997 • 600 citations

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1994 • 569 citations

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1992 • 543 citations

Angiogenic and HIV-Inhibitory Functions of KSHV-Encoded Chemokines

1997 • 479 citations

The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen

1997 • 447 citations

Transcription Mapping of the Kaposi’s Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Genome in a Body Cavity-Based Lymphoma Cell Line (BC-1)

1998 • 445 citations

A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

1997 • 437 citations

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase.

1993 • 436 citations

The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans.

1993 • 383 citations

KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway

1997 • 358 citations

Interferon-Induced Antiviral Actions and Their Regulation

1993 • 338 citations

Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2.

1992 • 325 citations

Autophosphorylation of the protein kinase dependent on double-stranded RNA.

1987 • 301 citations

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus.

1997 • 297 citations

Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin

1997 • 291 citations

Regulation of Type I Interferon Gene Expression by Interferon Regulatory Factor-3

1998 • 278 citations

Antiapoptotic and Oncogenic Potentials of Hepatitis C Virus Are Linked to Interferon Resistance by Viral Repression of the PKR Protein Kinase

1999 • 259 citations

KSHV and Kaposi's Sarcoma: The End of the Beginning?

1997 • 223 citations

Human Herpesvirus 8 Encodes an Interferon Regulatory Factor (IRF) Homolog That Represses IRF-1-Mediated Transcription

1998 • 217 citations

Functional Analysis of Human Herpesvirus 8-Encoded Viral Interferon Regulatory Factor 1 and Its Association with Cellular Interferon Regulatory Factors and p300

1999 • 211 citations

The Double Stranded RNA-Activated Protein Kinase Induced by Interferon: dsRNA-PK

1989 • 202 citations

Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI.

1989 • 197 citations

The Primary Sequence of Rhesus Monkey Rhadinovirus Isolate 26-95: Sequence Similarities to Kaposi's Sarcoma-Associated Herpesvirus and Rhesus Monkey Rhadinovirus Isolate 17577

2000 • 183 citations

Characterization of a Novel Human Herpesvirus 8-Encoded Protein, vIRF-3, That Shows Homology to Viral and Cellular Interferon Regulatory Factors

2000 • 178 citations

Kaposi’s Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor

1998 • 173 citations

Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation

1997 • 163 citations

The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo.

1995 • 147 citations

Expression of Human Herpesvirus 8-Encoded Cyclin D in Kaposi's Sarcoma Spindle Cells

1997 • 145 citations

Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cells.

1985 • 138 citations

Unique properties of a second human herpesvirus 8-encoded interferon regulatory factor (vIRF-2).

1999 • 126 citations

The Emerging Role of the Interferon-Induced PKR Protein Kinase as an Apoptotic Effector: A New Face of Death?

1999 • 108 citations

Cytosolic double-stranded RNA-dependent protein kinase is likely a dimer of partially phosphorylated Mr = 66,000 subunits.

1992 • 93 citations

Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells.

1992 • 93 citations

Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors

1999 • 91 citations

Purification and Activation of the Double-Stranded RNA-Dependent eIF-2 Kinase DAI

1989 • 64 citations

Virus interception of cytokine-regulated pathways

1999 • 62 citations

Role of the Vaccinia Virus E3L and K3L Gene Products in Rescue of VSV and EMCV from the Effects of IFN-α

1998 • 45 citations

Regulated Expression of the Interferon-Induced Protein Kinase p68 (PKR) by Vaccinia Virus Recombinants Inhibits the Replication of Vesicular Stomatitis Virus but Not That of Poliovirus

1996 • 40 citations

Identification of a 90-kDa polypeptide which associates with adenovirus VA RNAI and is phosphorylated by the double-stranded RNA-dependent protein kinase

1989 • 36 citations