The selective ablation of interleukin 2-producing cells isolated from transgenic mice.

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

1991 • 892 citations

Superantigens: Mechanism of T-Cell Stimulation and Role in Immune Responses

1991 • 783 citations

Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization.

1986 • 740 citations

The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene

1980 • 556 citations

Interleukin 2

1984 • 497 citations

Targeting of an inducible toxic phenotype in animal cells.

1988 • 252 citations

Production and characterization of monoclonal antibodies to human interleukin 2: strategy and tactics.

1983 • 203 citations

Autocrine growth of CD4+ T cells. Differential effects of IL-1 on helper and inflammatory T cells.

1988 • 183 citations

Antigen-specific activation of effector macrophages by IFN-gamma producing (TH1) T cell clones. Failure of IL-4-producing (TH2) T cell clones to activate effector function in macrophages.

1989 • 183 citations

Distinct functional phenotypes of cloned Ia-restricted helper T cells.

1985 • 171 citations

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.

1986 • 171 citations

B-cell stimulatory factor 1 and not interleukin 2 is the autocrine growth factor for some helper T lymphocytes.

1987 • 141 citations

Antigen-driven helper cell-independent cloned cytolytic T lymphocytes

1981 • 128 citations

[125I]deoxycytidine used in a rapid, sensitive, and specific assay for herpes simplex virus type 1 thymidine kinase

1977 • 91 citations

The assignment of chain specificities for anti-Ia monoclonal antibodies using L cell transfectants.

1986 • 83 citations

Promoter Region of Interleukin-2 Gene Undergoes Chromatin Structure Changes and Confers Inducibility on Chloramphenicol Acetyltransferase Gene During Activation of T Cells

1986 • 67 citations

Stimulation of all T cells bearing V_β1, V_β3, V_β11 and V_β12 by staphylococcal enterotoxin A

1990 • 66 citations

Differential activation of cytokine genes in normal CD4‐bearing T cells is stimulus dependent

1989 • 60 citations

An antigen receptor-driven, interleukin 2-independent pathway for proliferation of murine cytolytic T lymphocyte clones.

1986 • 58 citations

Evidence for IL-2 independent proliferation in human T cells.

1988 • 51 citations

PMA alone induces proliferation of some murine T cell clones but not others.

1986 • 28 citations

T Lymphocyte Activation

1998 • 23 citations

Teleocidin and phorbol ester tumor promoters exert similar mitogenic effects on human lymphocytes

1985 • 22 citations

Cloning and structure of a mouse interleukin-2 chromosomal gene

1986 • 16 citations

Functional activities of antibodies against brain‐associated T cell antigens II. Stimulation of T cell‐induced B cell proliferation

1982 • 16 citations

Subsets of CD4 T cells and B cell activation.

1989 • 12 citations

Immune recognition and effector function in subsets of CD4 T cells.

1988 • 6 citations