Polymorphism in alcohol‐metabolizing enzymes, glutathione S‐transferases and apolipoprotein E and susceptibility to alcohol‐induced cirrhosis and chronic pancreatitis

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

1994 • 1,319 citations

Glutathione S-Transferase Polymorphisms and Their Biological Consequences

2000 • 966 citations

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men.

1991 • 613 citations

Presence of Nonoxidative Ethanol Metabolism in Human Organs Commonly Damaged by Ethanol Abuse

1986 • 487 citations

Evidence of Genetic Predisposition to Alcoholic Cirrhosis and Psychosis: Twin Concordances for Alcoholism and Its Biological End Points by Zygosity among Male Veterans

1981 • 459 citations

A Plan for Tanganyika

1964 • 445 citations

PROSPECTIVE EVALUATION OF ALCOHOL ABUSE AND ALCOHOLIC LIVER INJURY IN MEN AS PREDICTORS OF DEVELOPMENT OF CIRRHOSIS

1984 • 411 citations

The effects of storage of blood and isolated DNA on the integrity of DNA

1987 • 275 citations

Genetic polymorphism of alcohol dehydrogenase in europeans: TheADH2*2 allele decreases the risk for alcoholism and is associated withADH3*1

2000 • 261 citations

Mechanisms of hydroxyl radical formation and ethanol oxidation by ethanol-inducible and other forms of rabbit liver microsomal cytochromes P-450.

1984 • 246 citations

Ethanol-inducible cytochrome P4502E1: Genetic polymorphism, regulation, and possible role in the etiology of alcohol-induced liver disease

1993 • 232 citations

Genetic polymorphism of cytochrome P4502E1 in a Swedish population

1993 • 189 citations

Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

1997 • 185 citations

Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in Chinese patients.

1994 • 165 citations

Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end-organ damage

1991 • 158 citations

Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes

1991 • 156 citations

Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in chinese patients

1994 • 145 citations

Regulation of the mammalian alcohol dehydrogenase genes

2000 • 138 citations

Polymorphism of Alcohol‐Metabolizing Genes Affects Drinking Behavior and Alcoholic Liver Disease in Japanese Men

1997 • 130 citations

Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease

1994 • 129 citations

Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in Chinese patients

1997 • 123 citations

GST1 gene deletion determined by polymerase chain reaction

1990 • 109 citations

The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol dehydrogenase genotype

1998 • 95 citations

Improved methods for genotype determination of human alcohol dehydrogenase (ADH) at ADH 2 and ADH 3 loci by using polymerase chain reaction-directed mutagenesis

1990 • 78 citations

Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis?

1999 • 78 citations

Analysis of cytochrome P450 2E1 genetic polymorphisms in relation to human lung cancer

1995 • 78 citations

Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to alcoholic liver cirrhosis.

1994 • 77 citations

Cystic fibrosis genotypes and alcoholic pancreatitis

1998 • 67 citations

Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes.

1994 • 57 citations

The natural history of alcoholic pancreatitis: update 1985.

1985 • 55 citations

Genotypes of Alcohol‐Metabolizing Enzymes and the Risk for Alcoholic Chronic Pancreatitis in Japanese Alcoholics

1996 • 53 citations

Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes

1994 • 51 citations

Polymorphisms of ethanol-oxidizing enzymes in alcoholics with inactive ALDH2

1996 • 44 citations

Lipid intolerance does not account for susceptibility to alcoholic and gallstone pancreatitis

1994 • 33 citations

Alcoholic Pancreatitis and Polymorphisms of the Variable Length Polythymidine Tract in the Cystic Fibrosis Gene

1999 • 33 citations

7 The inheritance of alcoholic liver disease

1998 • 22 citations

GENETIC POLYMORPHISM OF APOLIPOPROTEIN E IN CAUCASIAN ALCOHOLIC CIRRHOTICS

1994 • 7 citations