Fins, limbs, and tails: outgrowths and axial patterning in vertebrate evolution

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On the origin of species by means of natural selection, or, The preservation of favoured races in the struggle for life

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Sonic hedgehog mediates the polarizing activity of the ZPA

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Epithelial-Mesenchymal Interactions

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The proximo‐distal sequence of origin of the parts of the chick wing and the role of the ectoderm

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Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

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Hox genes and the evolution of vertebrate axial morphology

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Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

1994 • 801 citations

STUDIES ON THE STRUCTURE AND DEVELOPMENT OF VERTEBRATES

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Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb

1995 • 719 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

A positive feedback loop coordinates growth and patterning in the vertebrate limb

1994 • 702 citations

FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

1993 • 660 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

Early Vertebrates

1996 • 622 citations

Positional signalling and specification of digits in chick limb morphogenesis

1975 • 588 citations

Roles for FGF8 in the Induction, Initiation, and Maintenance of Chick Limb Development

1996 • 588 citations

Fibroblast growth factors induce additional limb development from the flank of chick embryos

1995 • 578 citations

Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut

1995 • 531 citations

The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor

1997 • 529 citations

Analysis of Hox gene expression in the chick limb bud

1996 • 480 citations

FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development

1994 • 470 citations

Induction of the LIM homeobox gene Lmx1 by WNT6a establishes dorsoventral pattern in the vertebrate limb

1995 • 469 citations

Colinearity and functional hierarchy among genes of the homeotic complexes

1994 • 450 citations

The Cuvier-Geoffroy debate : French biology in the decades before Darwin

1987 • 449 citations

HoxGenes and Chordate Evolution

1996 • 448 citations

Lateral and Axial Signals Involved in Avian Somite Patterning: A Role for BMP4

1996 • 416 citations

Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

1995 • 390 citations

Gene dosage-dependent effects of theHoxa-13andHoxd-13mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts

1997 • 360 citations

Involvement of FGF8 in initiation, outgrowth and patterning of the vertebrate limb

1996 • 335 citations

The mouse Engrailed-1 gene and ventral limb patterning

1996 • 321 citations

Differential induction of four msx homeobox genes during fin development and regeneration in zebrafish

1995 • 319 citations

Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: Dorsal signals regulate anteroposterior patterning

1995 • 318 citations

Hox gene expression in teleost fins and the origin of vertebrate digits

1995 • 315 citations

Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb

1996 • 314 citations

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway

1997 • 301 citations

Dorsal cell fate specified by chick Lmxl during vertebrate limb development

1995 • 287 citations

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.

1991 • 286 citations

eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus

1996 • 285 citations

Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation

1997 • 274 citations

Evidence of a role for T-☐ genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity

1996 • 271 citations

Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation.

1995 • 268 citations

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos

1989 • 264 citations

Basal teleosts and teleostean phylogeny

1997 • 260 citations

Hox genes and the diversification of insect and crustacean body plans

1995 • 259 citations

Zebrafish hox genes: genomic organization and modified colinear expression patterns in the trunk

1998 • 256 citations

The Devonian tetrapodAcanthostega gunnariJarvik: postcranial anatomy, basal tetrapod interrelationships and patterns of skeletal evolution

1996 • 255 citations

Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures

1994 • 245 citations

Regulation of number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary implications

1997 • 219 citations

Hox9 genes and vertebrate limb specification

1997 • 214 citations

Diversity of expression of engrailed-like antigens in zebrafish

1991 • 211 citations

Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb

1997 • 202 citations

The origin of vertebrate limbs

1994 • 202 citations

The origin of vertebrates

1955 • 202 citations

Reprogramming Hox Expression in the Vertebrate Hindbrain: Influence of Paraxial Mesoderm and Rhombomere Transposition

1996 • 193 citations

On the nature of limbs

1849 • 183 citations

Homeotic genes and positional signalling in the Drosophila viscera

1994 • 180 citations

Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage

1995 • 176 citations

Expansion of the Hox gene family and the evolution of chordates.

1993 • 176 citations

Function of posterior HoxD genes in the morphogenesis of the anal sphincter

1996 • 174 citations

Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity

1996 • 161 citations

Limbs: a model for pattern formation within the vertebrate body plan

1996 • 155 citations

Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes

1997 • 151 citations

Specific activation of mammalian Hox promoters in mosaic transgenic zebrafish.

1992 • 140 citations

Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb

1997 • 140 citations

Coordinated Expression of Abd-B Subfamily Genes of the HoxA Cluster in the Developing Digestive Tract of Chick Embryo

1995 • 139 citations

Scales of thelodont and shark-like fishes from the Ordovician of Colorado

1996 • 134 citations

The temnospondyl amphibians from the Viséan of East Kirkton, West Lothian, Scotland

1993 • 129 citations

Limbs generated at site of tail amputation in marbled balloon frog after vitamin A treatment

1992 • 122 citations

XII.—The Postcranial Skeleton of Rhipidistian Fishes ExcludingEusthenopteron

1970 • 120 citations

Conservation in the Hox code during morphological evolution.

1994 • 117 citations

On the Nature of Limbs

1849 • 110 citations

The Homeotic Transformation of Tails into Limbs in Rana temporaria by Retinoids

1993 • 102 citations

The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure

1997 • 98 citations

Teleost HoxD and HoxA genes: comparison with tetrapods and functional evolution of the HOXD complex

1996 • 93 citations

The Devonian actinopterygianCheirolepisAgassiz

1979 • 90 citations

The dawn of the vertebrates: characters versus common ascent in the rise of current vertebrate phylogenies [Palaeontological Association 1995 annual address]

1996 • 90 citations

Anterior Duplication of the Sonic hedgehog Expression Pattern in the Pectoral Fin Buds of Zebrafish Treated with Retinoic Acid

1995 • 89 citations

Conservation, Duplication, and Divergence of Developmental Genes During Chordate Evolution

1995 • 81 citations

Novel FGF receptor (Z‐FGFR4) is dynamically expressed in mesoderm and neurectoderm during early zebrafish embryogenesis

1995 • 79 citations

Expression of a homeobox gene product in normal and mutant zebrafish embryos: evolution of the tetrapod body plan

1990 • 78 citations

cash4, a novel achaete-scute homolog induced by Hensen's node during generation of the posterior nervous system.

1997 • 71 citations

A molecular approach to the evolution of vertebrate paired appendages

1996 • 68 citations

New Silurian and Devonian fork-tailed 'thelodonts' are jawless vertebrates with stomachs and deep bodies

1993 • 57 citations

Observations on Ctenurella (Ptyctodontida) and the classification of placoderm fishes

1986 • 45 citations

Limb Evolution: Fish fins or tetrapod limbs — a simple twist of fate?

1995 • 44 citations

Theoretical approaches to the analysis of homeobox gene evolution

1996 • 6 citations

Deleted Work

1955 • 0 citations