Microarray analysis of lipopolysaccharide-treated human neutrophils

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2001 • 4,673 citations

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1998 • 2,427 citations

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

1999 • 2,380 citations

The Transcriptional Program in the Response of Human Fibroblasts to Serum

1999 • 1,994 citations

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

1999 • 1,905 citations

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

1998 • 1,781 citations

A family of human receptors structurally related to Drosophila Toll

1998 • 1,735 citations

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

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Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide.

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Human Toll-like Receptor 2 Confers Responsiveness to Bacterial Lipopolysaccharide

1998 • 778 citations

Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators

1993 • 726 citations

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappa B that blocks TNFalpha -induced apoptosis

1999 • 721 citations

Overexpression of Manganese Superoxide Dismutase Suppresses Tumor Necrosis Factor-induced Apoptosis and Activation of Nuclear Transcription Factor-κB and Activated Protein-1

1998 • 580 citations

NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis

1999 • 574 citations

NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene.

1994 • 527 citations

The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products

2000 • 484 citations

Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

1996 • 416 citations

NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-like site.

1994 • 363 citations

Involvement of Caspases in Neutrophil Apoptosis: Regulation by Reactive Oxygen Species

1998 • 341 citations

Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2.

1993 • 336 citations

NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosis in Vitro

1999 • 329 citations

Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6.

1994 • 327 citations

Activation of the NF-κB Pathway by Inflammatory Stimuli in Human Neutrophils

1997 • 321 citations

The intratracheal administration of endotoxin and cytokines. I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1-, and TNF-induced inflammatory infiltrate.

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Selective activation and functional significance of p38α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils

1999 • 283 citations

Cell proliferation and apoptosis

1999 • 235 citations

Intratracheal Administration of Endotoxin and Cytokines

1994 • 215 citations

Accelerated Neutrophil Apoptosis in Mice Lacking A1-a, a Subtype of the bcl-2–related A1 Gene

1998 • 198 citations

Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells

1999 • 197 citations

Neutrophil migration during endotoxemia

1999 • 197 citations

Spontaneous Neutrophil Apoptosis Involves Caspase 3-mediated Activation of Protein Kinase C-δ

1999 • 186 citations

C/EBP, NF-kappa B, and c-Ets family members and transcriptional regulation of the cell-specific and inducible macrophage inflammatory protein 1 alpha immediate-early gene.

1993 • 183 citations

Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes

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Interference of BAD (Bcl-xL/Bcl-2-Associated Death Promoter)-Induced Apoptosis in Mammalian Cells by 14–3-3 Isoforms and P11

1997 • 176 citations

A Genomic and Proteomic Analysis of Activation of the Human Neutrophil by Lipopolysaccharide and Its Mediation by p38 Mitogen-activated Protein Kinase

2002 • 173 citations

IFN-gamma is produced by polymorphonuclear neutrophils in human uterine endometrium and by cultured peripheral blood polymorphonuclear neutrophils.

1998 • 141 citations

Calcium-binding protein S100A4 in health and disease

1998 • 139 citations

RNA expression patterns change dramatically in human neutrophils exposed to bacteria

2001 • 134 citations

Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4.

1996 • 114 citations

Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL.

1993 • 104 citations

A1 Is a Constitutive and Inducible Bcl-2 Homologue in Mature Human Neutrophils

1998 • 101 citations

Pulmonary Cytokine and Chemokine mRNA Levels after Inhalation of Lipopolysaccharide in C57BL/6 Mice

1998 • 90 citations

Apoptosis and cell division

2000 • 75 citations

LPS-induced expression of the human IL-1 receptor antagonist gene is controlled by multiple interacting promoter elements.

1994 • 64 citations

MCP-1 is selectively expressed in the late phase by cytokine-stimulated human neutrophils: TNF-α plays a role in maximal MCP-1 mRNA expression

1999 • 61 citations

Transcriptional regulation of TSG6, a tumor necrosis factor- and interleukin-1-inducible primary response gene coding for a secreted hyaluronan-binding protein.

1993 • 58 citations

The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation.

1993 • 57 citations

A NF-?B p65 subunit is indispensable for activating manganese superoxide: Dismutase gene transcription mediated by tumor necrosis factor-?

2000 • 53 citations

Regulation of p100 (NFKB2) expression in human monocytes in response to inflammatory mediators and lymphokines

1998 • 30 citations

Characterization of changes in gene expression associated with malignant transformation by the NF-κB family member, v-Rel

1997 • 18 citations

Post-processing of BLAST results using databases of clustered sequences

1997 • 9 citations

Expression of p21^waf1/cip1, mdm2 and p53 in vivo: analysis of cytological preparations

1996 • 5 citations