Circulating adhesion molecules and tumor necrosis factor receptor in multiple sclerosis: Correlation with magnetic resonance imaging

Rating neurologic impairment in multiple sclerosis

1983 • 14,011 citations

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

Circulating adhesion molecules in disease

1993 • 1,425 citations

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

1988 • 1,371 citations

Endothelial-Leukocyte Adhesion Molecules

1993 • 1,324 citations

Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.

1992 • 842 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

1992 • 832 citations

Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

1991 • 794 citations

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis.

1990 • 692 citations

Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells

1992 • 653 citations

BREAKDOWN OF THE BLOOD-BRAIN BARRIER PRECEDES SYMPTOMS AND OTHER MRI SIGNS OF NEW LESIONS IN MULTIPLE SCLEROSIS

1990 • 571 citations

E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro.

1992 • 519 citations

Anti—tumor necrosis factor therapy abrogates autoimmune demyelination

1991 • 434 citations

Soluble L-selectin is present in human plasma at high levels and retains functional activity.

1992 • 422 citations

Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbations?

1988 • 404 citations

Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis

1993 • 378 citations

Magnetic resonance imaging in monitoring the treatment of multiple sclerosis: concerted action guidelines.

1991 • 373 citations

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

1991 • 293 citations

The Dale E. McFarlin memorial lecture: The immunology of the multiple sclerosis lesion

1994 • 284 citations

Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis.

1993 • 277 citations

Vascular cell adhesion molecule 1 induces T-cell antigen receptor-dependent activation of CD4+T lymphocytes.

1991 • 234 citations

Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor‐immunoglobulin fusion proteins

1994 • 232 citations

MS: a CNS and systematic autoimmune disease

1989 • 231 citations

Characterization in vitro of a human tumor necrosis factor-binding protein. A soluble form of a tumor necrosis factor receptor.

1990 • 227 citations

Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis

1994 • 227 citations

Inflammatory mediators in demyelinating disorders of the CNS and PNS

1992 • 213 citations

Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM‐1

1993 • 186 citations

Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-α and blood-brain barrier damage

1993 • 180 citations

Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I

1995 • 177 citations

Elevated serum levels of tumor necrosis factor‐α in Guillain‐Barré syndrome

1993 • 117 citations

Tumor necrosis factor alpha production as a possible predictor of relapse in patients with multiple sclerosis.

1992 • 112 citations

Immune‐mediated demyelination

1993 • 99 citations

Serial analysis of circulating adhesion molecules and TNF receptor in serum from patients a with multinle sclerosis

1994 • 88 citations

The immune response in viral encephalitis.

1992 • 71 citations

Soluble ICAM‐1 serum levels in multiple sclerosis and viral encephalitis

1993 • 70 citations

Identification of a soluble form of a ligand for the lymphocyte homing receptor.

1992 • 64 citations

Increases levels of circulating intercellular adhesion molecule‐1 in multiple sclerosis and human T‐lymphotropic virus type I‐associated myelopathy

1993 • 56 citations

A monoclonal antibody-based enzyme immunoassay for quantitation of human tumor necrosis factor binding protein I, a soluble fragment of the 60 kDa TNF receptor, in biological fluids

1991 • 36 citations

Competitive PCR quantification of CD4, CD8, ICAM-1, VCAM-1, and MHC class II mRNA in the central nervous system during development and resolution of experimental allergic encephalomyelitis

1993 • 34 citations

The Role of T Cells in Multiple Sclerosis: Implications for Therapies Targeting the T Cell Receptor

1994 • 26 citations

Increased levels of soluble tumor necrosis factor receptor in patients with multiple sclerosis and HTLV-1-associated myelopathy

1994 • 23 citations

Binding of an SJL T cell clone specific for myelin basic protein to SJL brain microvessel endothelial cells is inhibited by anti-VLA-4 or its ligand, anti-vascular cell adhesion molecule 1 antibody

1993 • 15 citations