Identification and Characterization of Three Novel β1,3-N-Acetylglucosaminyltransferases Structurally Related to the β1,3-Galactosyltransferase Family

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

The scanning model for translation: an update.

1989 • 3,525 citations

ELAM-1 Mediates Cell Adhesion by Recognition of a Carbohydrate Ligand, Sialyl-Le ^x

1990 • 1,315 citations

Recognition by Elam-1 of the Sialyl-Le ^x Determinant on Myeloid and Tumor Cells

1990 • 976 citations

ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA

1990 • 712 citations

Glycoprotein glycosylation and cancer progression

1999 • 648 citations

Pathways of O-glycan biosynthesis in cancer cells

1999 • 545 citations

A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase.

1990 • 504 citations

Characterization of sialosylated Lewisx as a new tumor-associated antigen.

1984 • 503 citations

Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study.

1993 • 417 citations

ELFT: A gene that directs the expression of an ELAM-1 ligand

1990 • 338 citations

Expression cloning of a novel alpha 1,3-fucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes.

1994 • 329 citations

Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities.

1992 • 321 citations

Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen.

1992 • 312 citations

Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant

1994 • 311 citations

Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.

1992 • 295 citations

Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions

1999 • 291 citations

Molecular characterization of eukaryotic polysialyltransferase-1

1995 • 286 citations

Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion.

1991 • 281 citations

Structures of the O-Glycans on P-selectin Glycoprotein Ligand-1 from HL-60 Cells

1996 • 260 citations

Differential expression of five sialyltransferase genes in human tissues.

1994 • 246 citations

Molecular Glycobiology

1994 • 239 citations

Structure of sialylated fucosyl lactosaminoglycan isolated from human granulocytes.

1984 • 238 citations

Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain.

1995 • 237 citations

Cloning and Expression of a Proteoglycan UDP-Galactose:β-Xylose β1,4-Galactosyltransferase I

1999 • 227 citations

Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups.

1994 • 223 citations

Differential E-selectin-dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials.

1994 • 218 citations

Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase. Novel features at the 5′-end predict two translational start sites at two in-frame AUGs.

1988 • 217 citations

Molecular Cloning and Expression of a Novel β-1,6-N-Acetylglucosaminyltransferase That Forms Core 2, Core 4, and I Branches

1999 • 216 citations

cDNA Cloning and Expression of a Novel Human UDP- -acetyl-α-D-galactosamine

1996 • 212 citations

Cloning of a Human UDP-N-Acetyl-α-d-Galactosamine:PolypeptideN-Acetylgalactosaminyltransferase That Complements Other GalNAc-Transferases in Complete O-Glycosylation of the MUC1 Tandem Repeat

1998 • 209 citations

Isolation of GD3 synthase gene by expression cloning of GM3 alpha-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody.

1994 • 200 citations

Purification and cDNA Cloning of a Human UDP-N-acetyl-α- D-galactosamine:polypeptide N-Acetylgalactosaminyltransferase

1995 • 199 citations

Primary structure of Gal beta 1,3(4)GlcNAc alpha 2,3-sialyltransferase determined by mass spectrometry sequence analysis and molecular cloning. Evidence for a protein motif in the sialyltransferase gene family.

1992 • 191 citations

A Family of Human β4-Galactosyltransferases

1997 • 190 citations

Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection.

1993 • 187 citations

Three types of blood group I specificity among monoclonal anti-I autoantibodies revealed by analogues of a branched erythrocyte glycolipid.

1979 • 183 citations

Cloning and Characterization of a Close Homologue of Human UDP-N-acetyl-α-d-galactosamine:Polypeptide N-Acetylgalactosaminyltransferase-T3, Designated GalNAc-T6

1999 • 182 citations

A Family of Human β3-Galactosyltransferases

1998 • 180 citations

Polymerase chain reaction cloning of a developmentally regulated member of the sialyltransferase gene family

1993 • 180 citations

Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase.

1986 • 174 citations

Poly-N-acetyllactosaminyl O-glycans attached to leukosialin. The presence of sialyl Le(x) structures in O-glycans.

1992 • 169 citations

Cloning and expression of the Gal beta 1, 3GalNAc alpha 2,3-sialyltransferase.

1992 • 163 citations

Molecular Cloning of a Novel α2,3-Sialyltransferase (ST3Gal VI) That Sialylates Type II Lactosamine Structures on Glycoproteins and Glycolipids

1999 • 160 citations

Isolation and expression of a cDNA clone encoding a bovine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

1993 • 157 citations

Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines.

1986 • 156 citations

Biosynthesis of blood group i-active polylactosaminoglycans. Partial purification and properties of an UDP-GlcNAc:N-acetyllactosaminide beta 1—-3-N-acetylglucosaminyltransferase from Novikoff tumor cell ascites fluid.

1988 • 156 citations

Expression cloning of cDNA encoding a human β-1,3-N-acetylglucosaminyltransferase that is essential for poly-N-acetyllactosamine synthesis

1997 • 153 citations

Identification of the full-length coding sequence for human galactosyltransferase (β-N-acetylglucosaminide: β1,4-galactosyltransferase)

1988 • 152 citations

Expression Cloning and Functional Characterization of Human cDNA for Ganglioside GM3 Synthase

1998 • 150 citations

Improved method for fluorescence labeling of suger chains with sialic acid residues.

1990 • 150 citations

A Human STX cDNA Confers Polysialic Acid Expression in Mammalian Cells

1995 • 149 citations

Expression cloning of a GM3-specific alpha-2,8-sialyltransferase (GD3 synthase).

1994 • 145 citations

Expression of the developmental I antigen by a cloned human cDNA encoding a member of a beta-1,6-N-acetylglucosaminyltransferase gene family.

1993 • 144 citations

Cloning, Expression, and Characterization of a Novel UDP-galactose:β-N-Acetylglucosamine β1,3-Galactosyltransferase (β3Gal-T5) Responsible for Synthesis of Type 1 Chain in Colorectal and Pancreatic Epithelia and Tumor Cells Derived Therefrom

1999 • 141 citations

Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.

1998 • 140 citations

Human Homolog of Caenorhabditis elegans sqv-3 Gene Is Galactosyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans

1999 • 139 citations

Cloning and Expression of Human Galβ1,3(4)GlcNAc α2,3-Sialyltransferase

1993 • 133 citations

Purification, cDNA Cloning, and Expression of UDP-Gal: Glucosylceramide β-1,4-Galactosyltransferase from Rat Brain

1998 • 131 citations

Control of O-Glycan Branch Formation

2000 • 130 citations

Cloning and expression of a human gene encoding an N-acetylgalactosamine- 2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens

1999 • 127 citations

Cloning and Expression of a Novel, Tissue Specifically Expressed Member of the UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase Family

1998 • 127 citations

A novel human UDP‐N‐acetyl‐<scp>D</scp>‐galactosamine:polypeptide N‐acetylgalactosaminyltransferase, GalNAc‐T7, with specificity for partial GalNAc‐glycosylated acceptor substrates

1999 • 125 citations

Molecular cloning of a human cDNA encoding β-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc β-1,4-galactosyltransferase

1998 • 121 citations

Granulocytic differentiation of HL-60 cells is associated with increase of poly-N-acetyllactosamine in Asn-linked oligosaccharides attached to human lysosomal membrane glycoproteins

1990 • 120 citations

Expression cloning of a CMP-NeuAc:NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1'Cer alpha 2,8-sialyltransferase (GD3 synthase) from human melanoma cells.

1994 • 116 citations

Control of O-Glycan Branch Formation

1999 • 114 citations

Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase

1994 • 113 citations

Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1—3N-acetylglucosaminyltransferase.

1987 • 105 citations

Expression Cloning and Characterization of a Novel Murine α1,3-Fucosyltransferase, mFuc-TIX, That Synthesizes the Lewis x (CD15) Epitope in Brain and Kidney

1998 • 103 citations

Expression Cloning of Rat cDNA Encoding UDP-galactose:GD2 β1,3-galactosyltransferase That Determines the Expression of GD1b/GM1/GA1

1997 • 103 citations

Molecular Cloning of Siaα2,3Galβ1,4GlcNAc α2,8-Sialyltransferase from Mouse Brain

1995 • 103 citations

Molecular cloning and expression of GalNAc alpha 2,6-sialyltransferase.

1994 • 101 citations

Genomic Cloning and Expression of Three Murine UDP-galactose: β-N-Acetylglucosamine β1,3-Galactosyltransferase Genes

1998 • 97 citations

Purification and characterization of endo-beta-galactosidase from Escherichia freundii induced by hog gastric mucin.

1981 • 95 citations

Cloning of a Novel Member of the UDP-Galactose:β-N-Acetylglucosamine β1,4-Galactosyltransferase Family, β4Gal-T4, Involved in Glycosphingolipid Biosynthesis

1998 • 94 citations

A β-1,3- N -acetylglucosaminyltransferase with poly- N -acetyllactosamine synthase activity is structurally related to β-1,3-galactosyltransferases

1999 • 93 citations

Molecular Cloning of Brain-specific GD1α Synthase (ST6GalNAc V) Containing CAG/Glutamine Repeats

1999 • 92 citations

Synthesis of Poly-N-acetyllactosamine in Core 2 Branched O-Glycans

1998 • 89 citations

Expression Cloning of a Human GT3 Synthase

1996 • 89 citations

UDP-GlcNAc:Gal beta 1-4Glc(NAc) beta 1-3N-acetylglucosaminyltransferase. Identification and characterization in human serum.

1983 • 87 citations

Molecular Cloning of a Developmentally Regulated N-Acetylgalactosamine α2,6-Sialyltransferase Specific for Sialylated Glycoconjugates

1996 • 82 citations

Molecular Cloning and Expression of Human Galβ1,3GalNAc α2,3-Sialyltransferase (hST3Gal II)

1996 • 81 citations

Molecular Cloning and Functional Expression of Two Members of Mouse NeuAcα2,3Galβ1,3GalNAc GalNAcα2,6-Sialyltransferase Family, ST6GalNAc III and IV

1999 • 81 citations

A developmentally regulated member of the sialyltransferase family (ST8Sia II, STX) is a polysialic acid synthase

1995 • 80 citations

Molecular Cloning and Expression of a Fifth Type of α2,8-Sialyltransferase (ST8Sia V)

1996 • 78 citations

Carbohydrate binding specificities of several poly-N-acetyllactosamine-binding lectins

1990 • 77 citations

Molecular cloning of a novel human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, GalNAc-T8, and analysis as a candidate autosomal dominant hypophosphatemic rickets (ADHR) gene

2000 • 76 citations

Cloning of a Human UDP-galactose:2-Acetamido-2-deoxy-d-glucose 3β-Galactosyltransferase Catalyzing the Formation of Type 1 Chains

1998 • 72 citations

Extended type 1 chain glycosphingolipids: dimeric Lea (III4V4Fuc2Lc6) as human tumor-associated antigen

1991 • 70 citations

Molecular Cloning and Functional Expression of a Fifth-Type α2,3-sialyltransferase (mST3Gal V: GM3 synthase)

1998 • 70 citations

Molecular Cloning and Genomic Analysis of Mouse Galβ1,3GalNAc-specific GalNAc α2,6-Sialyltransferase

1996 • 67 citations

Expression Cloning of Mouse cDNA of CMP-NeuAc:Lactosylceramide α2,3-Sialyltransferase, an Enzyme That Initiates the Synthesis of Gangliosides

1999 • 64 citations

Poly-N-acetyllactosamine Synthesis in BranchedN-Glycans Is Controlled by Complemental Branch Specificity of i-Extension Enzyme and β1,4-Galactosyltransferase I

1999 • 60 citations

Biosynthesis of blood group I and i antigens in rat tissues. Identification of a novel beta 1-6-N-acetylglucosaminyltransferase.

1992 • 58 citations

Molecular Cloning and Expression of Mouse GD1α/GT1aα/GQ1bα Synthase (ST6GalNAc VI) Gene

2000 • 55 citations

Human α-1,3 Fucosyltransferase (FucT-VI) Gene Is Located at Only 13 kb 3′ to the Lewis Type Fucosyltransferase (FucT-III) Gene on Chromosome 19

1993 • 50 citations

Regulation of I-Branched Poly-N-Acetyllactosamine Synthesis

1999 • 44 citations

Preparative in vitro generation of lacto-series type 1 chain glycolipids catalyzed by β1 → 3-galactosyltransferase from human colonic adenocarcinoma Colo 205 cells

1989 • 27 citations

High-Level Expression and Purification of a Recombinant Human α-1,3-Fucosyltransferase in Baculovirus-Infected Insect Cells

1997 • 23 citations

β1-3-N-Acetylglucosaminyltransferase in Human Leukocytes: Properties and Role in Regulating Neolacto Glycosphingolipid Biosynthesis

1993 • 19 citations

Biosynthesis in vitro of core lacto-series glycosphingolipids by N-acetyl-d-glucosaminyltransferases from human colon carcinoma cells, Colo 205

1991 • 17 citations

Characterization of a β1 → 3-N-acetylglucosaminyltransferase associated with synthesis of type 1 and type 2 lacto-series tumor-associated antigens from the human colonic adenocarcinoma cell line SW403

1988 • 15 citations

The characterization of a UDP- N -acetylglucosamine: Gal β 1-4Glc(NAc) β 1-3 N -acetylglucosaminyltransferase in fluids from rat rete testis

1996 • 9 citations

Gas-Evaporated Small InSb Particles with the Wurtzite Structure

1994 • 3 citations