Human Granulocyte-Macrophage Colony-Stimulating Factor Enhancer Function Is Associated with Cooperative Interactions between AP-1 and NFATp/c

Current protocols in molecular biology

1988 • 4,543 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

1991 • 1,300 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

Identification of a Putative Regulator of Early T Cell Activation Genes

1988 • 933 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1993 • 769 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.

1991 • 543 citations

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1994 • 523 citations

Nuclear factor of activated T cells contains Fos and Jun

1992 • 495 citations

HEMOPOIETIC CELL GROWTH FACTORS AND THEIR RECEPTORS

1989 • 432 citations

Isolation of the Cyclosporin-Sensitive T Cell Transcription Factor NFATp

1993 • 415 citations

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1990 • 353 citations

Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.

1993 • 344 citations

Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.

1990 • 245 citations

The NFAT-1 DNA Binding Complex in Activated T Cells Contains Fra-1 and JunB

1993 • 215 citations

Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter.

1993 • 202 citations

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.

1993 • 201 citations

Signal transduction and gene control: the cAMP pathway.

1992 • 142 citations

p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells.

1993 • 139 citations

The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.

1993 • 131 citations

NF-AT-AP-1 and Rel-bZIP: Hybrid vigor and binding under the influence

1994 • 118 citations

The role of viral enhancer "core" motif-related sequences in regulating T cell receptor-gamma and -delta gene expression.

1993 • 79 citations

A conserved sequence in the T-cell receptor beta-chain promoter region.

1988 • 74 citations

Identification of a critical regulatory site in the human interleukin-3 promoter by in vivo footprinting

1994 • 60 citations

Functional importance of the cyclic AMP response element-like decamer motif in the CD8 alpha promoter.

1993 • 27 citations

CD3 delta enhancer. CREB interferes with the function of a murine CD3-delta A binding factor (M delta AF).

1994 • 16 citations

Single-step piperidine elution, cleavage, and recovery of premodified DNA electrotransferred on NA-45 membrane from mobility-shift gels

1993 • 3 citations