Drug induced encephalopathy in six epileptic patients: topiramate? valproate? or both?

Neuropsychological effects of epilepsy and antiepileptic drugs

2001 • 430 citations

ADVERSE DRUG REACTION MONITORING: DOING IT THE FRENCH WAY

1985 • 228 citations

Valproate-induced hyperammonemic encephalopathy in the presence of topiramate

2000 • 170 citations

Clinical Pharmacology of Topiramate: A Review

2000 • 141 citations

Topiramate as an Inhibitor of Carbonic Anhydrase Isoenzymes

2000 • 140 citations

Review Article: Carnitine, Valproate, and Toxicity

1991 • 137 citations

Asymptomatic Hyperammonemia in Patients Receiving Valproic Acid

1982 • 129 citations

Sodium Valproate-induced hyperammonemia without clinical hepatic dysfunction

1982 • 114 citations

Hyperammonaemic encephalopathy after initiation of valproate therapy in unrecognised ornithine transcarbamylase deficiency

1998 • 100 citations

Valproate-Induced Coma: Case Report and Literature Review

1993 • 96 citations

Low-dose topiramate in adults with treatment-resistant partial-onset seizures

2002 • 87 citations

Topiramate: A New Antiepileptic Drug

1997 • 86 citations

Stuporous Episodes During Treatment with Sodium Valproate: Report of Seven Cases

1982 • 85 citations

Serum and CSF Glutamine Levels in Valproate‐related Hyperammonemic Encephalopathy

2002 • 76 citations

Heterozygote ornithine transcarbamylase deficiency presenting as symptomatic hyperammonemia during initiation of valproate therapy

1992 • 75 citations

Topiramate Enhances the Risk of Valproate‐associated Side Effects in Three Children

2002 • 75 citations

Hepatic and renal contributions to valproic acid‐induced hyperammonemia

1988 • 72 citations

Effect of L-Carnitine Supplementation on Acute Valproate Intoxication

1996 • 61 citations

Factors associated with behavioral and cognitive abnormalities in children receiving Topiramate

2000 • 55 citations

Effects of anti‐epileptic drugs on glutamine synthetase activity in mouse brain

1999 • 46 citations

Liver carbonic anhydrase and urea synthesis the effect of diuretics

1986 • 43 citations

Impaired fatty acid oxidation in children on valproic acid and the effect of L‐carnitine

1993 • 42 citations

Carbamyl phosphate synthetase-l deficiency discovered after valproic acid-induced coma

1992 • 35 citations

A pooled analysis of adjunctive topiramate in refractory partial epilepsy

2003 • 28 citations

Long-Term Treatment with Sodium Valproate

1987 • 28 citations

Acute changes of blood ammonia may predict short‐term adverse effects of valproic acid

1984 • 25 citations

Free and Total Serum Valproate Concentrations: Their Relationship to Seizure Control, Liver Enzymes and Plasma Ammonia in Children

1986 • 14 citations

Clinical studies of topiramate

1999 • 9 citations