Topiramate Enhances the Risk of Valproate‐associated Side Effects in Three Children

Cytochrome P-450—Catalyzed Formation of Δ ⁴ -VPA, a Toxic Metabolite of Valproic Acid

1987 • 248 citations

Valproic acid hepatic fatalities.

1989 • 218 citations

Hematologic Toxicity of Sodium Valproate

2000 • 206 citations

Valproate-induced hyperammonemic encephalopathy in the presence of topiramate

2000 • 170 citations

Severe Hepatotoxicity During Valproate Therapy: An Update and Report of Eight New Fatalities

1994 • 132 citations

Comparison of the Steady‐State Pharmacokinetics of Topiramate and Valproate in Patients with Epilepsy During Monotherapy and Concomitant Therapy

1997 • 116 citations

Non‐Dose‐Related Side Effects of Valproate

1984 • 109 citations

Side effects of valproate

1988 • 95 citations

Adverse Effects of Valproate

1984 • 89 citations

Severe Hematologic Toxicity of Valproic Acid

1990 • 66 citations

Valproate Treatment and Platelet Function: The Role of Arachidonate Metabolites

1999 • 49 citations

Valproate-Induced Coma With Ketosis and Carnitine Insufficiency

1990 • 37 citations

Hypothermia and thermoregulatory derangements induced by valproic acid

2000 • 30 citations

Topiramate

1997 • 29 citations

Cerebral Blood Flow During Spike‐Wave Discharges

1995 • 20 citations