Stem‐cell factor in aplastic anemia: in vitro expression in bone marrow stroma and fibroblast cultures

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns.

1985 • 706 citations

Long-term culture of human bone marrow cells.

1980 • 624 citations

Aplastic Anemia

1999 • 515 citations

Review: Stratton Lecture 1990. Clinical implications of positive and negative hematopoietic stem cell regulators

1991 • 369 citations

Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo.

1985 • 343 citations

Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene product, stem cell factor.

1992 • 306 citations

Hematology: Basic Principles and Practice

1991 • 299 citations

Aplastic Anemia

1982 • 294 citations

From white spots to stem cells: the role of the Kit receptor in mammalian development

1993 • 206 citations

Soluble stem cell factor in human serum

1993 • 151 citations

Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential

1991 • 144 citations

Biologic significance of constitutive and subliminal growth factor production by bone marrow stroma

1992 • 139 citations

The hematopoietic defect in aplastic anemia assessed by long-term marrow culture

1990 • 133 citations

Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates

1991 • 133 citations

Treatment of severe aplastic anaemia with antilymphocyte globulin or bone-marrow transplantation.

1981 • 130 citations

The hematopoietic defect in aplastic anemia assessed by long-term marrow culture

1990 • 122 citations

Further evidence for lymphokine overproduction in severe aplastic anemia [see comments]

1988 • 81 citations

Diamond-blackfan anemia: in vitro response of erythroid progenitors to the ligand for c-kit

1991 • 77 citations

Functionally abnormal marrow stromal cells in aplastic anemia.

1985 • 68 citations

Functional Changes in Marrow Stromal Cells in Aplastic Anaemia

1985 • 60 citations

The pathophysiology of aplastic anemia.

1991 • 60 citations

Levels of soluble stem cell factor in serum of patients with aplastic anemia

1993 • 58 citations

The expression of cytokine and cytokine receptor genes in long‐term bone marrow culture in congenital and acquired bone marrow hypoplasias

1993 • 57 citations

Long‐term culture of aplastic anaemia bone marrow

1990 • 50 citations

Effect of stem cell factor on colony growth from acquired and constitutional (Fanconi) aplastic anemia

1992 • 50 citations

Hematopoietic growth factors released by marrow stromal cells from patients with aplastic anemia

1992 • 43 citations

Cytokine mRNA expression of bone marrow stromal cells from patients with aplastic anaemia and myelodysplastic syndrome

1993 • 42 citations

Hematopoietic growth factors released by marrow stromal cells from patients with aplastic anemia

1992 • 36 citations

Stem cell factor stimulates the in vitro growth of bone marrow cells from aplastic anemia patients

1992 • 36 citations

Bone marrow fibroblast function in relation to granulopoiesis in aplastic anaemia

1983 • 17 citations

Production of granulocyte colony‐stimulating factor and granulocyte/macrophage‐colony‐stimulating factor after interleukin‐1 stimulation of marrow stromal cell cultures from normal or aplastic anemia donors

1992 • 14 citations