Telomere Shortening With Aging in Human Liver

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

The American Journal of Human Genetics

1950 • 5,048 citations

Structure and function of telomeres

1991 • 3,524 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

1988 • 2,281 citations

Telomere length predicts replicative capacity of human fibroblasts.

1992 • 2,209 citations

Telomere reduction in human colorectal carcinoma and with ageing

1990 • 1,672 citations

Telomere end-replication problem and cell aging

1992 • 1,044 citations

TELOMERE LENGTH REGULATION

1996 • 1,010 citations

Distribution of organelles and membranes between hepatocytes and nonhepatocytes in the rat liver parenchyma. A stereological study.

1977 • 827 citations

Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes.

1993 • 743 citations

Progress in Liver Diseases

1965 • 697 citations

The rate of telomere sequence loss in human leukocytes varies with age

1998 • 652 citations

Telomere length and replicative aging in human vascular tissues.

1995 • 630 citations

Telomerase activity in normal leukocytes and in hematologic malignancies

1995 • 619 citations

In vivo loss of telomeric repeats with age in humans

1991 • 469 citations

Telomerase activity in gastric cancer.

1995 • 433 citations

Telomerase activity in normal human epithelial cells.

1996 • 248 citations

Gastrointestinal Epithelial Renewal

1977 • 243 citations

Telomerase activity in human intestine

1996 • 207 citations

Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis

1997 • 174 citations

Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease

1997 • 160 citations

Mitosis and differentiation in the stratified squamous epithelium of the rat esophagus

1965 • 149 citations

In situ hybridization for the detection of telomerase RNA in the progression from barrett's esophagus to esophageal adenocarcinoma

1998 • 108 citations

Telomerase activity in normal human endothelial cells.

1997 • 89 citations

Telomere length in human liver diseases

1996 • 85 citations

Cell renewal in the organs and tissues of the nongrowing adult mouse.

1970 • 66 citations

Telomerase activity in esophageal carcinoma

1997 • 48 citations

Telomere shortening with aging in human esophageal mucosa

1999 • 37 citations

Shortened Telomere Length in Hepatocellular Carcinomas and Corresponding Background Liver Tissues of Patients Infected with Hepatitis Virus

1996 • 16 citations

An Ultrastructural Study of Peroxidatic and Phagocytic Activities of Two Types of Sinusoidal Lining Cells in Rat Liver

1973 • 14 citations