Activation of macrophages in vivo and in vitro. Correlation between hydrogen peroxide release and killing of Trypanosoma cruzi.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Oxygen-Dependent Microbial Killing by Phagocytes

1978 • 2,519 citations

Increased superoxide anion production by immunologically activated and chemically elicited macrophages

1978 • 823 citations

H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factors.

1975 • 653 citations

Membrane flow during pinocytosis. A stereologic analysis.

1976 • 639 citations

The Activation of Mononuclear Phagocytes: Fact, Fancy, and Future

1978 • 609 citations

Antimicrobial mechanisms in neutrophilic polymorphonuclear leukocytes.

1975 • 583 citations

Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity.

1979 • 538 citations

ALTERATIONS OF MACROPHAGE FUNCTIONS BY MEDIATORS FROM LYMPHOCYTES

1971 • 507 citations

Hydrogen peroxide release from mouse peritoneal macrophages: dependence on sequential activation and triggering.

1977 • 488 citations

Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide.

1979 • 423 citations

Biochemical Criteria for Activated Macrophages

1978 • 406 citations

The concept of the activated macrophage.

1978 • 383 citations

Trypanosoma cruzi: mechanism of entry and intracellular fate in mammalian cells.

1976 • 309 citations

The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes

1976 • 276 citations

CHARACTERIZATION OF A LYMPHOCYTE FACTOR WHICH ALTERS MACROPHAGE FUNCTIONS

1973 • 226 citations

Trypanosoma cruzi: in vitro induction of macrophage microbicidal activity.

1978 • 173 citations

Mononuclear phagocytes : functional aspects

1980 • 172 citations

Studies on the selective lysis and purification of Trypanosoma cruzi.

1975 • 159 citations

Studies on migration inhibitory factor (MIF): Recovery of MIF activity after purification by gel filtration and disc electrophoresis

1970 • 139 citations

Evaluation of the horseradish peroxidase-scopoletin method for the measurement of hydrogen peroxide formation in biological systems

1977 • 135 citations

Effect of β-lapachone on superoxide anion and hydrogen peroxide production in Trypanosoma cruzi

1978 • 112 citations

Studies on isoniazid and tubercle bacilli. II. The growth requirements, catalase activities, and pathogenic properties of isoniazid-resistant mutants.

1954 • 104 citations

Characterization of human migration inhibitory factor (MIF) from antigen-stimulated lymphocytes

1972 • 97 citations

Lipid peroxidation and the generation of free radicals, superoxide anion, and hydrogen peroxide in β-lapachone-treated Trypanosoma cruzi epimastigotes

1978 • 86 citations

Virulence in the guinea-pig, susceptibility to hydrogen peroxide, and catalase activity of isoniazid-sensitive tubercle bacilli from South Indian and British patients

1963 • 85 citations

METABOLIC AND FUNCTIONAL STUDIES ON ACTIVATED MOUSE MACROPHAGES

1973 • 85 citations

Trypanosoma cruzi: modification of macrophage function during infection.

1977 • 80 citations

Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages.

1975 • 75 citations

An approach to the development of new drugs for African trypanosomiasis.

1978 • 74 citations

Correlation of Increased Metabolic Activity, Resistance to Infection, Enhanced Phagocytosis, and Inhibition of Bacterial Growth by Macrophages from Listeria- and BCG-Infected Mice

1972 • 73 citations

Studies on the metabolism of the protozoa. 4. Metabolism of the parasitic flagellate Strigomonas oncopelti

1955 • 71 citations

Characterization of macrophage activation factor, a lymphokine that causes macrophages to become cytotoxic for tumor cells

1978 • 66 citations

Activation of human blood monocytes by products of sensitized lymphocytes.

1974 • 64 citations

Two Migration Inhibitory Factors with Different Chromatographic Behavior and Isoelectric Points

1977 • 54 citations

Partial Characterization of Murine Migration Inhibitory Factor (MIF)

1976 • 49 citations

Inhibition of the respiration of Trypanosoma rhodesiense by thiols

1956 • 48 citations

Effect of lymphocyte mediators on macrophages in vitro. A correlation of morphological and cytochemical changes.

1973 • 46 citations

Human migration inhibitory factor: purification and immunochemical characterization.

1978 • 38 citations

Alteration of some functional and metabolic characteristics of resident mouse peritoneal macrophages by lymphocyte mediators.

1978 • 37 citations

In vitro quantitation of cell-mediated immunity in guinea-pigs by macrophage reduction of nitro-blue tetrazolium.

1976 • 35 citations

Effect of beta-lapachone on hydrogen peroxide production in Trypanosoma cruzi.

1978 • 28 citations

Role of hydrogen peroxide and peroxidase in the cytotoxicity of Trypanosoma dionisii by human granulocytes

1978 • 22 citations

The relationship between the catalase activity, hydrogen peroxide sensitivity, and isoniazid resistance of mycobacteria.

1956 • 22 citations

Stimulation of the hexose monophosphate shunt independent of hydrogen peroxide and superoxide production in rabbit alveolar macrophages during phagocytosis

1977 • 21 citations

Relationship of Catalase Activity to Virulence in Pasteurella pestis

1949 • 17 citations

Observations on the Trypanocidal Actionin Vitroof Solutions of Glutathione and Ascorbic Acid

1937 • 15 citations

Chemical characterization of products of activated lymphocytes.

1978 • 14 citations

The effects of some sulfhydryl compounds on growth of catalase-positive and catalase-negative tubercle bacilli.

1956 • 13 citations

Effect of beta-lapachone on hydrogen peroxide production in Trypanosoma cruzi.

1978 • 10 citations