The SCF ubiquitin ligase protein Slimb regulates centrosome duplication in Drosophila

Genetic instabilities in human cancers

1998 • 4,165 citations

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

1998 • 1,740 citations

Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient Cells

1999 • 814 citations

Abnormal Centrosome Amplification in the Absence of p53

1996 • 802 citations

GADD45 induction of a G ₂ /M cell cycle checkpoint

1999 • 607 citations

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

1998 • 512 citations

Requirement of Cdk2-Cyclin E Activity for Repeated Centrosome Reproduction in Xenopus Egg Extracts

1999 • 505 citations

A ubiquitin ligase complex essential for the NF-kappa B, Wnt/Wingless, and Hedgehog signaling pathways

1999 • 427 citations

Cyclin-dependent kinase control of centrosome duplication

1999 • 423 citations

A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators

1998 • 419 citations

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

1999 • 388 citations

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

1999 • 329 citations

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis

1990 • 291 citations

SCF and APC: the Yin and Yang of cell cycle regulated proteolysis

1998 • 271 citations

Genes controlling essential cell-cycle functions in Drosophila melanogaster.

1989 • 255 citations

Cytoplasmic Dynein Is Required for the Nuclear Attachment and Migration of Centrosomes during Mitosis inDrosophila

1999 • 230 citations

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

1999 • 201 citations

Abnormal Spindle Protein, Asp, and the Integrity of Mitotic Centrosomal Microtubule Organizing Centers

1999 • 167 citations

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

1999 • 165 citations

P-Element Insertion Alleles of Essential Genes on the Third Chromosome of Drosophila melanogaster Correlation of Physical and Cytogenetic Maps in Chromosomal Region 86E-87F

1997 • 158 citations

Cloning of a gene encoding an antigen associated with the centrosome in Drosophila

1988 • 141 citations

The Homeotic Target Gene centrosomin Encodes an Essential Centrosomal Component

1996 • 127 citations

Hsp90 is a core centrosomal component and is required at different stages of the centrosome cycle in Drosophila and vertebrates

2000 • 125 citations

Centrosomes and cancer

1999 • 113 citations

Nek2B, a novel maternal form of Nek2 kinase, is essential for the assembly or maintenance of centrosomes in early Xenopus embryos

2000 • 86 citations

Centrosomes and cancer

1999 • 76 citations

ANALYSIS OF THE CHROMOSOME ABERRATIONS INDUCED BY X-RAYS IN SOMATIC CELLS OF DROSOPHILA MELANOGASTER

1974 • 75 citations

slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development

1998 • 64 citations

Genome stability: Keeping the centrosome cycle on track

1996 • 51 citations

Mitotic Regulators Govern Progress through Steps in the Centrosome Duplication Cycle

1999 • 51 citations

Association of Human SCFSKP2Subunit p19SKP1with Interphase Centrosomes and Mitotic Spindle Poles

1999 • 50 citations

The centrosome

1999 • 48 citations

Detection of S-phase cells in tissue sections by in situ DNA replication

2000 • 23 citations

Centrioles reveal their secrets

1999 • 19 citations