Phosphatidylcholine Synthesis Influences the Diacylglycerol Homeostasis Required for Sec14p-dependent Golgi Function and Cell Growth
Data up to Jan 2025
Total Citations Per Year
Abstract
References (52)
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
1951 • 319,299 citations
Methods in yeast genetics
1979 • 7,824 citations
The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid
1960 • 2,598 citations
Biochemistry of Lipids, Lipoproteins and Membranes
2021 • 1,420 citations
Form and function of phospholipids
1973 • 1,072 citations
Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.
1986 • 999 citations
An essential role for a phospholipid transfer protein in yeast Golgi function
1990 • 534 citations
[76] β-d-Fructofuranoside fructohydrolase from yeast
1975 • 455 citations
SAC1-like Domains of Yeast SAC1,INP52, and INP53 and of Human Synaptojanin Encode Polyphosphoinositide Phosphatases
1999 • 382 citations
The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex.
1989 • 381 citations
EUKARYOTIC PHOSPHOLIPID BIOSYNTHESIS
1995 • 371 citations
Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein
1991 • 348 citations
Direct Involvement of Phosphatidylinositol 4-Phosphate in Secretion in the Yeast Saccharomyces cerevisiae
1999 • 285 citations
Identification of a Non-mitochondrial Phosphatidylserine Decarboxylase Activity (PSD2) in the Yeast Saccharomyces cerevisiae
1995 • 261 citations
THE ENZYMATIC FORMATION OF LECITHIN FROM CYTIDINE DIPHOSPHATE CHOLINE AND d-1,2-DIGLYCERIDE
1958 • 258 citations
Essential role for diacylglycerol in protein transport from the yeast Golgi complex
1997 • 257 citations
Cloning and expression of a novel phosphatidylethanolamine N-methyltransferase. A specific biochemical and cytological marker for a unique membrane fraction in rat liver
1993 • 232 citations
Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele.
1993 • 226 citations
Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes.
1987 • 214 citations
Newly made phosphatidylserine and phosphatidylethanolamine are preferentially translocated between rat liver mitochondria and endoplasmic reticulum.
1991 • 206 citations
sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis.
1985 • 179 citations
Cloning of a gene (PSD1) encoding phosphatidylserine decarboxylase from Saccharomyces cerevisiae by complementation of an Escherichia coli mutant.
1993 • 166 citations
Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects
1998 • 161 citations
Different Effects of Enzyme-generated Ceramides and Diacylglycerols in Phospholipid Membrane Fusion and Leakage
1996 • 152 citations
The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity.
1995 • 150 citations
Identification and Characterization of a Gene Encoding Phospholipase D Activity in Yeast
1996 • 150 citations
Identification of a Novel Family of Nonclassic Yeast Phosphatidylinositol Transfer Proteins Whose Function Modulates Phospholipase D Activity and Sec14p-independent Cell Growth
2000 • 142 citations
A Role for Phospholipase D (Pld1p) in Growth, Secretion, and Regulation of Membrane Lipid Synthesis in Yeast
1998 • 138 citations
Secretory Vesicle Budding from the Trans-Golgi Network Is Mediated by Phosphatidic Acid Levels
1998 • 138 citations
Pleiotropic Alterations in Lipid Metabolism in Yeastsac1Mutants: Relationship to “Bypass Sec14p” and Inositol Auxotrophy
1999 • 137 citations
Yeast Sec14p Deficient in Phosphatidylinositol Transfer Activity Is Functional In Vivo
1999 • 130 citations
Role of the Yeast Phosphatidylinositol/Phosphatidylcholine Transfer Protein (Sec14p) in Phosphatidylcholine Turnover andINO1 Regulation
1997 • 125 citations
Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine
1999 • 121 citations
The gene encoding the phosphatidylinositol transfer protein is essential for cell growth.
1990 • 118 citations
SAC1 Encodes a Regulated Lipid Phosphoinositide Phosphatase, Defects in Which Can Be Suppressed by the Homologous Inp52p and Inp53p Phosphatases
2000 • 118 citations
Cloning, Genomic Organization, and Characterization of a Human Cholinephosphotransferase
2000 • 115 citations
Isolation and Characterization of the Saccharomyces cerevisiae EKI1 Gene Encoding Ethanolamine Kinase
1999 • 93 citations
Phosphatidylcholine biosynthesis in Saccharomyces cerevisiae. Regulatory insights from studies employing null and chimeric sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases.
1994 • 86 citations
Scanning Alanine Mutagenesis of the CDP-alcohol Phosphotransferase Motif of Saccharomyces cerevisiaeCholinephosphotransferase
1998 • 86 citations
Purification and characterization of choline/ethanolamine kinase from rat liver.
1990 • 85 citations
sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases in Saccharomyces cerevisiae. Nucleotide sequence of the EPT1 gene and comparison of the CPT1 and EPT1 gene products.
1991 • 83 citations
CDP-choline:1,2-diacylglycerol cholinephosphotransferase
1997 • 82 citations
The sn-1,2-diacylglycerol cholinephosphotransferase of Saccharomyces cerevisiae. Nucleotide sequence, transcriptional mapping, and gene product analysis of the CPT1 gene.
1990 • 80 citations
Phosphatidylinositol transfer proteins: the long and winding road to physiological function
1998 • 79 citations
Synthesis and Intracellular Transport of Aminoglycerophospholipids in Permeabilized Cells of the Yeast, Saccharomyces cerevisiae
1995 • 78 citations
sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases in Saccharomyces cerevisiae
1991 • 73 citations
SEC14-dependent Secretion inSaccharomyces cerevisiae
1999 • 50 citations
Regulation and function of PLDs in yeast
1999 • 45 citations
Functional redundancy of CDP-ethanolamine and CDP-choline pathway enzymes in phospholipid biosynthesis: ethanolamine-dependent effects on steady-state membrane phospholipid composition in Saccharomyces cerevisiae
1994 • 42 citations
CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
1997 • 38 citations
Chimeric enzymes. Structure-function analysis of segments of sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases.
1994 • 35 citations
Form and Function.
1999 • 1 citations