Dual EBNA1 promoter usage by Epstein-Barr virus in human B-cell lines expressing unique intermediate cellular phenotypes

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells

1985 • 1,257 citations

The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation

1986 • 927 citations

Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cells.

1987 • 735 citations

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1990 • 585 citations

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

1986 • 558 citations

Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts

1992 • 493 citations

Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation.

1989 • 491 citations

Immunofluorescent studies of the development of pre‐B cells, B lymphocytes and immunoglobulin isotype diversity in humans

1977 • 487 citations

Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells.

1991 • 415 citations

Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes

1992 • 360 citations

Two species of human Fcε receptor II ( ): Tissue-specific and IL-4-specific regulation of gene expression

1988 • 345 citations

Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1

1990 • 319 citations

Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells

1985 • 274 citations

An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking.

1994 • 262 citations

Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6.

1986 • 222 citations

The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle

1989 • 218 citations

A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome.

1988 • 199 citations

Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes.

1990 • 196 citations

Early events in Epstein-Barr virus infection provide a model for B cell activation.

1985 • 193 citations

Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex

1987 • 183 citations

DNA of Epstein-Barr virus VIII: B95-8, the previous prototype, is an unusual deletion derivative

1980 • 173 citations

Epstein-Barr virus nuclear antigen 2 activates transcription of the terminal protein gene

1991 • 165 citations

Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.

1983 • 165 citations

Two related Epstein-Barr virus membrane proteins are encoded by separate genes

1989 • 161 citations

EBNA-2 transactivates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virus

1991 • 158 citations

Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen 1 transcriptional initiation site.

1991 • 153 citations

Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes

1993 • 146 citations

Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection.

1991 • 142 citations

Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinoma

1990 • 141 citations

Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA element

1991 • 124 citations

Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes.

1989 • 122 citations

Three transcriptionally distinct forms of epstein-barr virus latency in somatic cell hybrids: Cell phenotype dependence of virus promoter usage

1992 • 114 citations

The EB virus genome in Daudi Burkitt's lymphoma cells has a deletion similar to that observed in a non-transforming strain (P3HR-1) of the virus.

1984 • 109 citations

Epstein-Barr virus DNA is amplified in transformed lymphocytes

1979 • 107 citations

Epstein-Barr virus (EBV) gene expression in EBV-positive peripheral T-cell lymphomas

1993 • 101 citations

Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B

1993 • 100 citations

Selective suppression of the transcription of ribosomal genes in mouse‐human hybrid cells

1979 • 91 citations

Delineation of the cis-acting element mediating EBNA-2 transactivation of latent infection membrane protein expression

1991 • 89 citations

Structure and function of the Epstein-Barr virus BZLF1 protein

1990 • 88 citations

The Epstein-Barr virus (EBV) nuclear antigen 1 BamHI F promoter is activated on entry of EBV-transformed B cells into the lytic cycle

1992 • 77 citations

Transcription of the Epstein-Barr virus genome during latency in growth-transformed lymphocytes

1990 • 76 citations

Characterization of Productive and Sterile Transcripts from the Immunoglobulin Heavy-Chain Locus: Processing of μ_m and μ_s mRNA

1983 • 63 citations

A Transformation-Incompetent, Nuclear Antigen 2-Deleted Epstein-Barr Virus Associated with Replicative Infection

1991 • 62 citations

Transcription of the Epstein-Barr virus gene EBNA-1 from different promoters in nasopharyngeal carcinoma and B-lymphoblastoid cells

1992 • 60 citations

Host cell and EBNA-2 regulation of Epstein-Barr virus latent-cycle promoter activity in B lymphocytes

1992 • 48 citations

Lymphoblastoid cell lines and burkitt‐lymphoma‐derivee cell lines differ in the expression of a second epstein‐barr virus encoded nuclear antigen

1986 • 46 citations

Regulation of IgM and IgD expression in human B-lineage cells.

1991 • 42 citations

Molecular basis of the cell-surface expression of immunoglobulin mu chain without light chain in human B lymphocytes.

1987 • 35 citations

The B95-8 isolate of Epstein-Barr virus arose from an isolate with a standard genome

1982 • 30 citations

Human cell lines containing Epstein-Barr virus but distinct from the common B cell lymphoblastoid lines.

1979 • 27 citations

Analysis of surface mu-chain expression in human lymphoblastoid cell lines that do not produce light chains.

1984 • 16 citations

Differential regulation of membrane and secretory mu chain synthesis in human beta cell lines. Regulation of membrane mu or secreted mu.

1982 • 16 citations

Conserved patterns of somatic mutation and secondary V_H gene rearrangement create aberrant lg-encoding genes in Epstein-Barr virus-transformed and normal human B lymphocytes

1992 • 12 citations