Analysis of the yeast transcriptome with structural and functional categories: characterizing highly expressed proteins

Basic local alignment search tool

1990 • 87,358 citations

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

SCOP: A structural classification of proteins database for the investigation of sequences and structures

1995 • 6,372 citations

Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization

1998 • 4,811 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

Life with 6000 Genes

1996 • 4,125 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Correlation between Protein and mRNA Abundance in Yeast

1999 • 3,800 citations

The complete genome sequence of the gastric pathogen Helicobacter pylori

1997 • 3,529 citations

Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation

1999 • 2,990 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Systematic determination of genetic network architecture

1999 • 2,535 citations

The Transcriptional Program of Sporulation in Budding Yeast

1998 • 1,876 citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

Genome‐wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms

1998 • 1,498 citations

IDENTIFYING NONPOLAR TRANSBILAYER HELICES IN AMINO ACID SEQUENCES OF MEMBRANE PROTEINS

1986 • 1,495 citations

MIPS: a database for genomes and protein sequences

2000 • 1,295 citations

Structural patterns in globular proteins

1976 • 1,286 citations

A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization.

1996 • 1,146 citations

Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation

1998 • 957 citations

Characterization of the Yeast Transcriptome

1997 • 941 citations

The detection and classification of membrane-spanning proteins

1985 • 854 citations

Extracting regulatory sites from the upstream region of yeast genes by computational analysis of oligonucleotide frequencies 1 1Edited by G. von Heijne

1998 • 749 citations

Protein Data Bank (PDB): Database of Three-Dimensional Structural Information of Biological Macromolecules

1998 • 717 citations

Helix propensities of the amino acids measured in alanine‐based peptides without helix‐stabilizing side‐chain interactions

1994 • 601 citations

Global response of Saccharomyces cerevisiae to an alkylating agent

1999 • 426 citations

The relationship between protein structure and function: a comprehensive survey with application to the yeast genome

1999 • 402 citations

Empirical statistical estimates for sequence similarity searches

1998 • 341 citations

Predicting Gene Regulatory Elements in Silico on a Genomic Scale

1998 • 340 citations

Data management and analysis for gene expression arrays

1998 • 300 citations

Protein folds and functions

1998 • 217 citations

A structural census of genomes: comparing bacterial, eukaryotic, and archaeal genomes in terms of protein structure

1997 • 184 citations

Cluster analysis and data visualization of large-scale gene expression data.

1998 • 183 citations

Structural assignments to the Mycoplasma genitalium proteins show extensive gene duplications and domain rearrangements

1998 • 170 citations

A multipurpose transposon system for analyzing protein production, localization, and function in Saccharomyces cerevisiae

1997 • 164 citations

How many membrane proteins are there?

1998 • 143 citations

How representative are the known structures of the proteins in a complete genome? A comprehensive structural census

1998 • 136 citations

MIPS: a database for protein sequences and complete genomes

1998 • 135 citations

Patterns of protein-fold usage in eight microbial genomes: A comprehensive structural census

1998 • 120 citations

Identifying distantly related protein sequences

1997 • 55 citations

Comprehensive, comprehensible, distributed and intelligent databases: current status.

1998 • 43 citations

Archaeal Aminoacyl-tRNA Synthesis: Diversity Replaces Dogma

1999 • 42 citations