Tube Travel: The Role of Proteases in Individual and Collective Cancer Cell Invasion

Tumour-cell invasion and migration: diversity and escape mechanisms

2003 • 3,069 citations

Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations

2002 • 2,711 citations

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

2007 • 1,446 citations

Compensation mechanism in tumor cell migration

2003 • 1,360 citations

Reassessing Epithelial to Mesenchymal Transition as a Prerequisite for Carcinoma Invasion and Metastasis

2006 • 1,041 citations

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

2007 • 970 citations

Emerging roles of proteases in tumour suppression

2007 • 771 citations

The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

2007 • 619 citations

Dynamic Interactions of Cortactin and Membrane Type 1 Matrix Metalloproteinase at Invadopodia: Defining the Stages of Invadopodia Formation and Function

2006 • 590 citations

Regulation of Cell Invasion and Morphogenesis in a Three-Dimensional Type I Collagen Matrix by Membrane-Type Matrix Metalloproteinases 1, 2, and 3

2000 • 588 citations

Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

2004 • 572 citations

Collective cell migration in morphogenesis and cancer

2004 • 432 citations

ROCK- and Myosin-Dependent Matrix Deformation Enables Protease-Independent Tumor-Cell Invasion In Vivo

2006 • 431 citations

Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases

2003 • 419 citations

Focalized proteolysis: spatial and temporal regulation of extracellular matrix degradation at the cell surface

1996 • 331 citations

Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro.

1995 • 239 citations

Migration of highly aggressive MV3 melanoma cells in 3-dimensional collagen lattices results in local matrix reorganization and shedding of alpha2 and beta1 integrins and CD44.

1997 • 236 citations

FUNCTIONAL IMAGING OF TUMOR PROTEOLYSIS

2005 • 69 citations

Functional imaging of pericellular proteolysis in cancer cell invasion

2004 • 63 citations