Acidic fibroblast growth factor-Pseudomonas exotoxin chimeric protein elicits antiangiogenic effects on endothelial cells.

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation.

1974 • 775 citations

Angiogenesis Inhibition and Tumor Regression Caused by Heparin or a Heparin Fragment in the Presence of Cortisone

1983 • 622 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.

1988 • 571 citations

Endothelial proliferation in tumours and normal tissues: Continuous labelling studies

1984 • 562 citations

Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma

1991 • 523 citations

Functional domains of pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli

1987 • 449 citations

Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti‐cancer therapeutic agents

1991 • 441 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Recombinant Toxins for Cancer Treatment

1991 • 308 citations

ANGIOGENESIS: INITIATION AND CONTROL*

1982 • 264 citations

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol

1990 • 233 citations

Endothelial growth factors and extracellular matrix regulate DNA synthesis through modulation of cell and nuclear expansion

1987 • 225 citations

Differential expression of markers for endothelial cells, pericytes, and basal lamina in the microvasculature of tumors and granulation tissue.

1991 • 222 citations

Novel growth regulatory factors and tumour angiogenesis

1991 • 162 citations

Targeted Toxin Therapy for the Treatment of Cancer

1989 • 158 citations

Pseudomonas exotoxin: chimeric toxins

1989 • 129 citations

Mutational analysis of domain I of Pseudomonas exotoxin. Mutations in domain I of Pseudomonas exotoxin which reduce cell binding and animal toxicity.

1988 • 87 citations

Cytotoxic effects of a recombinant chimeric toxin on rapidly proliferating vascular smooth muscle cells.

1991 • 62 citations

Comparative endocrinology-paracrinology-autocrinology of human adult large vessel endothelial and smooth muscle cells

1988 • 60 citations

Cytotoxic activity of chimeric proteins composed of acidic fibroblast growth factor and Pseudomonas exotoxin on a variety of cell types

1991 • 31 citations

Analysis of sequences in domain II of Pseudomonas exotoxin A which mediate translocation

1991 • 29 citations