Activation of the Saccharomyces cerevisiae Filamentation/Invasion Pathway by Osmotic Stress in High-Osmolarity Glycogen Pathway Mutants

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The mitogen-activated protein kinase signal transduction pathway

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Nonfilamentous C. albicans Mutants Are Avirulent

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Multifunctional yeast high-copy-number shuttle vectors

1992 • 1,656 citations

Raf-1 activates MAP kinase-kinase

1992 • 1,308 citations

How Proteolysis Drives the Cell Cycle

1996 • 1,277 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: Regulation by starvation and RAS

1992 • 1,184 citations

A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf

1993 • 1,086 citations

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

1992 • 980 citations

MAP Kinase Pathways in the Yeast Saccharomyces cerevisiae

1998 • 939 citations

Protein kinase cascades activated by stress and inflammatory cytokines

1996 • 722 citations

One-step transformation of yeast in stationary phase

1992 • 683 citations

Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor

1995 • 649 citations

GPD1, Which Encodes Glycerol-3-Phosphate Dehydrogenase, Is Essential for Growth under Osmotic Stress in Saccharomyces cerevisiae, and Its Expression Is Regulated by the High-Osmolarity Glycerol Response Pathway

1994 • 630 citations

Osmotic Activation of the HOG MAPK Pathway via Ste11p MAPKKK: Scaffold Role of Pbs2p MAPKK

1997 • 569 citations

GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway.

1994 • 539 citations

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

1998 • 496 citations

FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation

1990 • 437 citations

Conditional Expression of the Mitogen-activated Protein Kinase (MAPK) Phosphatase MKP-1 Preferentially Inhibits p38 MAPK and Stress-activated Protein Kinase in U937 Cells

1997 • 435 citations

MAP Kinases with Distinct Inhibitory Functions Impart Signaling Specificity during Yeast Differentiation

1997 • 434 citations

Combinatorial Control Required for the Specificity of Yeast MAPK Signaling

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The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae

1998 • 386 citations

The YDp plasmids: A uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae

1991 • 342 citations

Signal transduction within the nucleus by mitogen-activated protein kinase.

1992 • 323 citations

A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae

1989 • 298 citations

Signalling in the Yeasts: An Informational Cascade with Links to the Filamentous Fungi

1998 • 298 citations

Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.

1992 • 292 citations

A Second Osmosensing Signal Transduction Pathway in Yeast

1995 • 278 citations

Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous- growth signalling pathway

1997 • 270 citations

Regulation of the Saccharomyces cerevisiae HOG1 Mitogen-Activated Protein Kinase by the PTP2 and PTP3 Protein Tyrosine Phosphatases

1997 • 266 citations

MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae.

1994 • 241 citations

Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product.

1992 • 236 citations

Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.

1996 • 229 citations

The Cdk-Activating Kinase (CAK) from Budding Yeast

1996 • 220 citations

FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction.

1991 • 211 citations

Yeast RLM1 Encodes a Serum Response Factor-Like Protein That May Function Downstream of the Mpk1 (Slt2) Mitogen-Activated Protein Kinase Pathway

1995 • 194 citations

Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK

1998 • 189 citations

A Cyclin-Dependent Kinase-Activating Kinase (CAK) in Budding Yeast Unrelated to Vertebrate CAK

1996 • 174 citations

Two Protein-tyrosine Phosphatases Inactivate the Osmotic Stress Response Pathway in Yeast by Targeting the Mitogen-activated Protein Kinase, Hog1

1997 • 173 citations

Civ1 (CAK In Vivo), a Novel Cdk-Activating Kinase

1996 • 172 citations

Signaling in the Yeast Pheromone Response Pathway: Specific and High-Affinity Interaction of the Mitogen-Activated Protein (MAP) Kinases Kss1 and Fus3 with the Upstream MAP Kinase Kinase Ste7

1996 • 164 citations

SMK1, a developmentally regulated MAP kinase, is required for spore wall assembly in Saccharomyces cerevisiae.

1994 • 164 citations

Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae.

1997 • 143 citations

Identification of MAP Kinase Domains by Redirecting Stress Signals into Growth Factor Responses

1996 • 127 citations

Complete nucleotide sequence of a gene conferring polymyxin B resistance on yeast: similarity of the predicted polypeptide to protein kinases.

1987 • 106 citations

Yeast thioredoxin genes

1991 • 102 citations

Positioning of cell growth and division after osmotic stress requires a map kinase pathway

1994 • 100 citations

The Osmoregulatory Pathway Represses Mating Pathway Activity in Saccharomyces cerevisiae: Isolation of a FUS3 Mutant That Is Insensitive to the Repression Mechanism

1996 • 99 citations

Yeast STE7, STE11, and STE12 genes are required for expression of cell-type-specific genes.

1988 • 92 citations

The mating factor response pathway regulates transcription of TEC1, a gene involved in pseudohyphal differentiation of Saccharomyces cerevisiae

1998 • 38 citations

Transcriptional Regulation of theSMK1Mitogen-Activated Protein Kinase Gene during Meiotic Development inSaccharomyces cerevisiae

1998 • 37 citations

A reliable and sensitive method for non-radioactive Northern blot analysis of nerve growth factor mRNA from brain tissues

1995 • 33 citations