The Ets-Domain Transcription Factor Spdef Promotes Maturation of Goblet and Paneth Cells in the Intestinal Epithelium

In silico prediction of protein-protein interactions in human macrophages

2014 • 11,120 citations

Significance analysis of microarrays applied to the ionizing radiation response

2001 • 10,393 citations

Identification of stem cells in small intestine and colon by marker gene Lgr5

2007 • 5,173 citations

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

2008 • 1,638 citations

Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

2005 • 1,457 citations

Bmi1 is expressed in vivo in intestinal stem cells

2008 • 1,144 citations

Control of endodermal endocrine development by Hes-1

2000 • 1,135 citations

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

1996 • 1,124 citations

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

2003 • 982 citations

Notch signals control the fate of immature progenitor cells in the intestine

2005 • 870 citations

Requirement of Math1 for Secretory Cell Lineage Commitment in the Mouse Intestine

2001 • 857 citations

Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

2009 • 675 citations

Wnt signalling induces maturation of Paneth cells in intestinal crypts

2005 • 625 citations

Expression Pattern of Wnt Signaling Components in the Adult Intestine

2005 • 549 citations

Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation

2005 • 291 citations

Intestine-Specific Ablation of Mouse atonal homolog 1 (Math1) Reveals a Role in Cellular Homeostasis

2007 • 291 citations

Direct regulation of intestinal fate by Notch

2005 • 288 citations

PDEF, a Novel Prostate Epithelium-specific Ets Transcription Factor, Interacts with the Androgen Receptor and Activates Prostate-specific Antigen Gene Expression

2000 • 269 citations

Examining the Role of Paneth Cells in the Small Intestine by Lineage Ablation in Transgenic Mice

1997 • 267 citations

SPDEF regulates goblet cell hyperplasia in the airway epithelium

2007 • 261 citations

Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine

2005 • 249 citations

Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells

2005 • 115 citations

Reduced PDEF Expression Increases Invasion and Expression of Mesenchymal Genes in Prostate Cancer Cells

2007 • 101 citations

Novel Role for PDEF in Epithelial Cell Migration and Invasion

2005 • 84 citations

Prostate-Derived ETS Factor Is a Mediator of Metastatic Potential through the Inhibition of Migration and Invasion in Breast Cancer

2007 • 70 citations

Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen.

2001 • 69 citations

Prostate-derived Ets transcription factor (PDEF) downregulates survivin expression and inhibits breast cancer cell growth in vitro and xenograft tumor formation in vivo

2006 • 50 citations

Prostate derived Ets transcription factor shows better tumor-association than other cancer-associated molecules

2004 • 34 citations

Analysis of the 2.0 Å Crystal Structure of the Protein−DNA Complex of the Human PDEF Ets Domain Bound to the Prostate Specific Antigen Regulatory Site^,

2005 • 31 citations

Prostate-derived Ets Factor Is Overexpressed in Serous Epithelial Ovarian Tumors

2006 • 23 citations

Molecular cloning and characterization of murine Mpgc60, a gene predominantly expressed in the intestinal tract

1998 • 11 citations